Whose studies determined that DNA was the genetic material instead of Protein?
Griffin, Hershey and Chase
Whose Research is this? What was the impact?
Griffith. He determined that DNA was the heritbale information in DNA because it was changed and reverted back to its original form.
Whose work was this? What was the impact?
Hershey and Chase
Who determined the structure and mechanism of replication of DNA?
Watson & Crick
Rosalind Franklin & Wilkins
Building Blocks of DNA
Components of a Nucelotide
Nitrogenous Base (4 Different Types)
Polarity of DNA
Base Pairs in DNA
How many base pairs are in each turn of the Double helix?
DNA Strands run _____ To each other
How much DNA is in a human cell
2m of DNA
How large is a typical Cell?
Packaged DNA consists of
Single Molecule of DNA+Associated Packaging proteins (Histones)+ Scaffolding Proteins
Bacteria typically have _____, _____ chromosome.
Name This Image
Each Chromosome is made up of
Single, long DNA Molecule+accompanying proteins (Chromatin)
Karyotypes are arranged in what pattern?
From largest to smallest, except the sex chromosomes, which are always #23
Functions of Chromosomes:
To Carry Genes
Sites Where Replication begins
help overcome the End-Replication problem
During Mitosos, DNA is compacted to what size?
During Interphase, DNA is compacted to what size?
~500-400x ( Less compacted than in mitosis)
Basic Unit of Eukaryotic Chromosomes that consist of a length of DNA coiled around a core of histones.
Histone core of nucleosomes are made of
4 different Histone proteins
What is the function of Linker Histone H1
Helps pack nucleosome cores more tightly
Levels of Chromosome Packing
Nucleosomes (beads on a string) packaged into Chromatin Fiber
Chromatin Fiber packaged into folded loops
Folded loops packaged into Mitotic Chromosome
Use ATP to Change DNA POsition along Histone cores of nucleosome
Can make DNA More or less accessible
True or false: Chromatin-remodeling Complexes are actvated during mitosis
Acetyl groups ___ chromatin, making it more accessible
Histone Acetyl Transferases (HATs)
Add Acetyl Groups to Histones