UNIT 3 objective 1: need for extemporaneous compounding Flashcards
the preparation of a dosage form for a patient is based on individual need
extemporaneous
detection, assessment, understanding, and prevention of adverse effects or any other possible medicine related problems
pharamcovigilance
what are 6 causes of ADRs?
- medicine administration
- non-adherence
- overdose
- off label use
- drug abuse
- use of traditional and complementary medications
what medication caused children to die form choking on the tablets in ethiopia?
albendazole
what is the intended delivery site for IR formulations?
the stomach
what is the intended delivery site for DR or EC formulations?
small intestine
what is the intended delivery site for XR formulations?
small intestine
what is the intended absorption site for IR formulations?
small intestine
what is the intended absorption site for DR or EC formulations?
small intestine
what is the intended absorption site for XR formulations?
small intestine
what is the intended delivery profile for IR formulations?
Rapid: API dissolved in <30 mins
what is the intended delivery profile for DR or EC formulations?
Rapid: API dissolved in <30 mins
what is the intended delivery profile for XR formulations?
Prolonged: API dissolves gradually over hours
what is the leading reason as to why manufacturing companies creating pediatric drug formulations?
lack of investment in drug development for this population
