Unit 4 - Review Flashcards
(59 cards)
1902
Genes are gaining acceptance as a concept
1930 - Boveri and Sutton
Established the chromosome theory (drosophila)
1952 - Hershey and Chase
Proved that DNA not protein is the information carrier
1953 - Watson and Crick
Proposed the double helix
Chromosome
Combination of DNA and protein
Histone
Protein around which DNA is wound (thick spool)
Nucleotide
A unit of DNA consisting of: a nitrogen base, a sugar, a phosphate
Purine
A nitrogen base consisting of 2 rings - Adenine (DNA, RNA) and Guanine (DNA, RNA)
Pyrimidine
A nitrogen base consisting of 1 ring - Cytosine (DNA, RNA), Thymine (DNA), and Uracil (RNA)
Who bonds with who?
A=T (makes 2 bonds)
G=_C (makes 3 bonds)
DNA polymerase
The enzyme that copies DNA to DNA
Conservative method
One daughter cell gets both original strands and the other daughter cell gets both new strands (this is the wrong one because one is entirely new DNA, and the other is made of old DNA strands)
Semi-conservative method
Each daughter cell gets one original and one copied strand (this one is the right one)
Protein synthesis
DNA to proteins - three types of RNA: mRNA (messenger RNA), tRNA (transfer RNA), and rRNA (ribosomal RNA)
Transcription
DNA to RNA
1. Happens in the nucleus
2. DNA is copied to mRNA (the copy of DNA that goes out of the Nucleus)
3. RNA polymerase - the enzyme that copies DNA to RNA
Translation
RNA to Amino Acid sequence
1. Happens in the cytoplasm
2. Ribosome - the thing that translates RNA into Amino Acids
3. Codon - a section of DNA that codes for a particular amino
4. Anti-codon - the complementary part of tRNA which binds to the mRNA
-tRNA - transfer RNA brings an amino acid to the mRNA/ribosome complex
-rRNA - ribosomal RNA - RNA is part of the ribosome
Template
“Original” from which a copy is made
Exon and Intron
RNA editing (keep exons, toss introns)
Frame shift mutations
-Messes up ALL successive codons
-Insertion- mutation where a nucleotide is added
-Deletion- mutation where a nucleotide is removed
Mutation
An uncorrected change in the DNA which remains
Substitution mutation
Mutation where nucleotide is replaced - only messes up ONE codon
Interphase (Mitosis)
The period of time that the cell spends growing and going about ordinary business (not dividing) this includes copying the DNA
Chromosomes are indistinguishable (can’t see them)
Mitosis
Produces 2 identical cells which have not only the same amount of DNA but precisely the same chromosomes (2 copies of each gene)
Meiosis
Produces 4 cells which each have only one half of the DNA of the original cell (one copy of each chromosome; one copy f each gene)Process by which gametes (sex cell) are formed