Unit 5:The Mouse Flashcards

1
Q

genus species of mouse

A

mus musculus (Mus=theif)

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2
Q

organ used in mice to detect pheromones, located in roof of mouth

A

vomeronasal organ (Jacobsons organ)

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3
Q

what is brown fat

A

hibernation fat, has increased blood flow for warmth

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4
Q

spot behind eye which we can draw blood from

what is this called in rats?

A

orbital sinus

rats= retro-orbital plexus

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5
Q

what is barbering

A

when dominant mouse pulls hair from face and body of other mice

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6
Q

when female mice develop nipples

A

9 days old

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7
Q

how many pairs of nipples females have

A

5

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8
Q

why rodents mice commonly get abdominal hernias

A

have an open inguinal canal which allows the spermatic cord to pass thro

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9
Q

whitten effect

A

group of females synchronize estrus cycles in presence of male

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10
Q

bruce effect

A

recently bred females may abort pregnancy when exposed to strange male (usu w/in 4 days of breeding)

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11
Q

what may cause cannibalism of neonates in mice

A

high-pitched sounds, little nesting material, and if disturbed; you should leave then 2 days undisturbed, preferably a week

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12
Q

what is the “milk spot” on neonate mice

A

see full stomach on left side of abdomen in healthy mice

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13
Q

how are nude mice produced? what research are they useful in

A

occur naturally (genetic defect), have deficient immune systems therefore useful in immune studies and cancer research

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14
Q

how to diagnose pinworm

A

do take prep on perianal region

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15
Q

what causes tyzzers

A

poor sanitation, overcrowding, stress

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16
Q

why tyzzers is hard to get rid of

A

produce spores, gram neg

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17
Q

what is Sendai virus

A

resp infection, compromises immune system, deadly

18
Q

what is ectromelia

A

mouse pox, affects v old and v young mice

19
Q

3 forms of ectromelia

A

acute- diarrhea, conjunctivitis, swelling of face and extremities, fatal
chronic- cutaneous rash leading to swelling and limb necrosis
Latent- older mice only, harbor in intestinal tract and spread (carriers)

20
Q

how to do intraperitoneal injection

diff between rat and mouse

A

anesthetize, scruff in dorsal recumb., point head towards floor, insert needle in lower right quadrant in mice (avoid spleen)
lower left in rats to avoid cecum

21
Q

why we do not withhold food before anesthetizing mice

A

fast metabolism, would go in shock

22
Q

mice (and rats) have __ digits on front feet __ digits on back

A

4 front, 5 back

23
Q

difference between galbladder in mice and rats

A

rats do not have, mice do

24
Q

mouse lifespan

A

12-36 months

25
mouse dental formula
same as rat; I 1/1 C0/0 M3/3
26
how long mouse gestation, how big are litters?
19-21 days (have ab 6-16 pups)
27
weaning age in rats and mice
21days (18-21 in mice)
28
what are hybrid mice
cross of 2 inbred strains
29
how transgenic mice are created
inject DNA from one animal into fertilized egg of another
30
what is murine colonic hyperplasia
a gram neg bacteria that causes explosive diarrhea, prolapsed rectum. treat w antibiotics
31
signs of tyzzers
anorexia, dehydration, diarrhea
32
how to restrain mice
grab base of tail, scruff, hold tail w pinkie finger
33
a bubble of fluid under the skin is referred to as what
a bleb
34
how to give SQ injection on mouse
scruff, allow it to hang onto cage w front paws, insert into tent base parallel to body
35
how to draw blood from mouse tail
warm mouse, anesthetize, restrain, cut off up to 1 cm of tail tip, collect in hematocrit tube, cauterize or apply pressure
36
list all blood collection options for mice
tail, jugular, dorsal pedal vein, orbital sinus, facial vein
37
how to do facial and dorsal pedal vein blood collection
nick vein
38
how to collect blood from orbital sinus is mice
anesthetize, stick hematocrit tube in lateral canthus at 45 degree angle
39
most humane euthanasia method
OD of isoflurane (other methods the same as rat methods)
40
Age mice become sexually mature
6 weeks