Unit 5 Tumor Markers Flashcards
(26 cards)
CEA
epithelial ovarian cancer
CA-125
use to monitor the progression of ovarian neoplasms
Estrogen
Leydig cell tumor
Thecoma
granulosa cell tumor
AFP
yolk sac tumor, teratoma
HCG
choriocarcinoma, hydatidiform mole (more in complete), teratoma, embryonal carcinoma
schistosomiasis with bladder lesion
squamous cell carcinoma of bladder
Benign testicular tumor in 4-12 y.o.
teratoma
placental alkaline phosphatase
seminoma and testicular carcinoma in situ
schiller duval bodies
yolk sac tumor
placetal ALP
seminoma
PAP + PSA +/- ALP
prostatic adenocarcinoma
Reinke Crystals
Leydig cell tumor
Androblastoma
Sertoli cell tumor
WT1 or WT2
Chromosome 11, Wilms Tumor
MEN2A or 2B + VHL, urinary VML
pheochromocytoma
Homovanillic acid (HVA), bombesin, N-myc
neuroblastoma
RET, BRAF mutations
papillary carcinoma of thyroid
calcitonin, MEN2A, RET
medullary carcinoma of thyroid
Gastrin secreting and MEN1 assoc.
Zollinger-Ellison Syndrome
MEN1
Parathyroid tumors, pituitary tumors, pancreatic endocrine tumors (zollinger-ellison, VIPoma, glucagonoma)
MEN2A
medullary thyroid carcinoma, pheochromocytoma, parathyroid hyperplasia
MEN2B
medullary thyroid carcinoma, pheochromocytoma, oral/intestinal ganglioneuromatosis, marfanoid habitus
Call Exner bodies + estrogen/progesterone
Granulosa Cell tumor
HCG + LDH
Dysgerminoma
