Unit 7: Cell cycle Flashcards

(50 cards)

1
Q

Interphase (G1, S, G2)

A

first phase of the cell cycle, cell prepares to divide; G1-growth, S-DNA replication, G2-prep for division

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2
Q

cell division

A

the process of splitting a parent cell into two daughter cells

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3
Q

mitosis (PMAT)

A

the phase of the cell cycle where the nucleus divides in two, made of four sub phases: prophase, metaphase, anaphase, and telophase

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4
Q

prophase

A

chromatin condenses into chromosomes, nucleus breaks down, spindles form

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5
Q

metaphase

A

chromosomes aligned in middle with spindles attached

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6
Q

anaphase

A

spindles pull chromosomes apart towards opposite ends of cells

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7
Q

telophase

A

nucleus reforms, chromosomes start to un-condense into chromatin , cell starts to pinch in to divide cytoplasm

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8
Q

cytokinesis

A

the division of the cytoplasm (and cytoplasmic organelles), normally overlaps with telophase

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9
Q

cell plate

A

forms during cytokinesis in plant cells in the middle, new membrane and cell wall build off cell plate to form two new cells

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10
Q

cleavage furrow

A

the pinched in area that is created when animals cells undergo cytokinesis

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11
Q

centrioles & centrosomes

A

centrioles are an organelle that produce spindles to aid in cell division, have two structures, and two of them during cell division; centrosomes are the area surrounding centrioles

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12
Q

spindle fibers

A

a system of microtubules that attach to chromosomes and help pull them apart in mitosis, form a fanning shape

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13
Q

parent cell

A

the original cell, before division

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14
Q

daughter cell

A

the two new cells produced by cell division

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15
Q

Gap 0

A

a phase outside of the cell cycle where cells “rest” (don’t divide), may happen so cell can differentiate, doesn’t have enough resources, organism reached maturity

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16
Q

cell differentiation

A

the process by which cells become specialized to perform a certain function

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17
Q

apoptosis

A

programmed cell death, cell and chromatin shrink, membrane breaks up, surrounding cells clean up remains

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18
Q

stem cells

A

unspecialized cells from which differentiated cells develop, adult stem cells are multipotent (can become a limited number of cell types), embryonic stem cells are pluripotent (can become any body cell type in body)

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19
Q

cancer

A

a condition casued by the loss of control over cell growth and division

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20
Q

chromosome

A

composed of two chromatids/ condensed chromatin, carries genetic information from parent to offspring

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21
Q

histone proteins

A

the proteins around which DNA coils to form chromatin

22
Q

chromatid

A

one half of a chromosome, joined by centromere

23
Q

chromatin

A

DNA coiled around histone proteins

24
Q

centromere

A

the protein that holds two chromatids together to make a chromosome

25
DNA
the basic form of genetic information, made of nucleotides joined into long strands, double helix
26
complementary base pairs
DNA base pairs only bond with one other base (so they come in approximately equal proportions); adenine (A) with thymine (T), and guanine (G) with cytosine (C)
27
pyrimidines
one ringed DNA bases, C and T
28
purines
double ringed DNA bases, A and G
29
nucleotide
Nucleic acid monomer, the building blocks of DNA, composed of a sugar, phosphate group, and nitrogenous base
30
antiparallel
DNA strands run parallel to each other but in opposite directions (5' to 3' vs 3' to 5')
31
3' end vs 5' end
numbers correspond to carbon atoms in sugar molecules, 5' end attaches to phosphate of next nucleotide
32
deoxyribose
the 5 carbon sugar found in DNA nucleotides
33
double helix
the shape of DNA, a twisted ladder
34
Chargraff's rule
base pair rule, percentage of A=T and percentage of G=C
35
DNA replication
the process of a cell duplicating its DNA in order to divide
36
semi-conservative
describes DNA replication, in each new DNA molecule there is one new and one original strand
37
origin of replication
the point where two DNA strands start separating in order to replicate
38
replication fork
the fork shaped produced at the origin of replication where two DNA strands split
39
DNA helicase
the enzyme that "unzips" (separates) DNA strands by breaking hydrogen bonds
40
DNA polymerase
the enzyme that attaches to RNA primers and adds new DNA nucleotides onto DNA in the 5' to 3' direction following the base pair rule
41
DNA ligase
the enzyme that joins together okazaki fragments (connects nucleotides)
42
DNA nuclease
the enzyme that removes RNA primers (DNA polymerase replaces them with DNA)
43
leading strand
builds continuoulsy, 5' end farthest from helicase
44
lagging strand
builds in chunks, 5' end closest to helicase
45
Okazaki fragments
the DNA fragments that are built on the lagging strand
46
parent DNA
the original DNA strand that goes into replication
47
daughter DNA
the new DNA strand produced in DNA replication with one original strand (from parent) and one new strand (built in replication)
48
Totipotent
can become any type of cell and develop an organism on their own, think toti=total, ex: zygote cells (earliest stage of development) can turn into extraembryonic tissues (ex: placenta) or any cell type in the organism
49
Pluripotent
can become any type of cell in the organism, cannot develop an organism on their own, think pluri=plural, ex: embryonic stem cells can turn into type of cell/tissue in the organism but not extraembryonic tissues
50
Multipotent
can be become certain types of specialized cells, think multi, ex: adult stem cells-depending on location can become certain types of cells (skin, blood, etc)