Urinary System Flashcards

0
Q

What is the outer portion of he parenchyma of the kidney

A

Cortex

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1
Q

What are the two hormones produced by the urinary system

A

Renin

Erythropoietin

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2
Q

What is the inner portion of the parenchyma of the kidney

A

Medulla

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3
Q

What is the functional unit of the kidney

A

Nephron

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4
Q

What are the two parts of the nephron

A

Renal corpuscle

Tubular part

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5
Q

Main function of the renal corpuscle

A

Filtration

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6
Q

Main function of the tubular part

A

Absorption and secretion

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7
Q

Two parts of the renal corpuscle

A

Glomerulus

Bowmans capsule

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8
Q

What are the two poles of the renal corpuscle

A

Vascular pole

Urinary pole

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9
Q

What can be found at the vascular pole of the renal corpuscle

A

Afferent vessels enter
Efferent vessels exit
Afferent branch and form glomerulus

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10
Q

What can be found at the urinary pole of the renal corpuscle

A

Beginning of tubular part

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11
Q

What is the outer layer of Bowmans capsule made of

A

Simple squamous epithelium

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12
Q

What is the inner layer of Bowmans capsule made of

A

Podocytes

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13
Q

What is the filtration barrier between blood and urinary space in the glomerulus

A

Basement membrane

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14
Q

What is the composition of glomerular filtrate

A

Similar to plasma but contains almost no protein

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15
Q

Where will you find mesangial cells

A

Within the capillary walls of the glomerulus

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16
Q

What receptors do mesangial cells have on them

A

Angiotensin 2

Atrial naturetic factor

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17
Q

What functions do mesangial cells have

A

Structural support
Synthesize extracellular matrix
Endocytosis
Control blood flow

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18
Q

What type of epithelium does the proximal convoluted have

A

Simple cuboidal epithelium

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19
Q

What are some of the characteristics of the epithelium of the proximal convoluted tubule

A

Numerous mitochondria
Abundant microvili
Abundant infoldings

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20
Q

What is absorbed back in the proximal convoluted tubules

A

Glucose
Small proteins
Amino acids
85%of water and NaCl

21
Q

What is secreted in the proximal convoluted tubules

A

Creatinine
Organic acids
Organic bases

22
Q

What are the 4 potential parts of the loop of Henley

A

Thick descending limb
Thin descending limb
Thin ascending limb
Thick ascending limb

23
Q

What are the two types of nephrons based on loop of Henley and location of the renal corpuscle

A

Cortical nephrons

Juxtamedullary nephrons

24
What creates the hyperosmotic gradient in the medulla?
Juxtamedullary nephrons | Specifically the selective permeability of the thin ascending and descending loops to water and NaCl
25
What is the epithelium of the distal convoluted tubule
Simple cuboidal
26
What are some of the characteristics of the epithelium of the distal convoluted tubule
Mitochondria NO BRUSH BORDER Basal membrane infoldings
27
What is aldosterone dependent in the distal convoluted tubules
Absorb sodium | Secrete potassium
28
What is acid base balance dependent in the distal convoluted tubules
Secrete hydrogen and ammonium
29
What are the three cell types of the juxtaglomerular apparatus
Cells of macula densa JG cells Extraglomerular mesangial cells
30
What is the macula densa
A modified segment of the wall of the distal convoluted tubule
31
What is the function of the cells of the macula densa
They are sensitive to ionic content and water volume of the tubular fluid
32
What do JG cells secrete
Renin
33
What are JG cells
Modified smooth muscle cells of the afferent arteriole
34
What activates the renin-angiotensin- aldosterone system
Juxtaglomerular apparatus
35
What connects a distal convoluted tubule to a collecting duct
Collecting tubule
36
What type of epithelium makes up the collecting tubules and ducts
Simple cuboidal which turns to columnar
37
What are the two cell types present in collecting tubule/duct epithelium
Light cells | Dark cells
38
Where are light cells located
Throughout collecting ducts and tubules
39
Where are dark cells located
Cortical region
40
What do dark cells do
Secrete hydrogen ion or bicarbonate
41
Ducts becomes permeable to water in the presence of what
ADH
42
What is the main artery that supplies blood to the cortex/medulla
Renal artery
43
What branch of renal artery gives of afferent arterioles
Interlobar arteries
44
What is important about the vasa recta arteries
They make straight hair pin turns and descend out into the medulla alongside the loop of Henley helping maintain the osmotic gradient of the medulla
45
What do all the veins of the kidney drain into?
Renal vein
46
Urine is no longer modified once it reaches where
Leaves collecting duct
47
What is the lining of the ureter
Transitional epithelium
48
What are the two muscle layers of the bladder
``` Inner layer (longitudinal) Outer layer (circular) ```
49
What is the ring like muscle arrangement at the opening of the urethra
Internal urethral sphincter
50
What is the epithelium of the female urethra
Transitional to stratified squamous
51
What is the transition of epithelium of the male urethra
Transitional Pseudostratified columnar Stratified squamous