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Flashcards in Uveitis Deck (51):
0

Whats the fa finding in birdshot?

"Quenching" of the vessels= dye leaving vessels quickly

1

Whats used for prophylaxis of pcp?

Bactrim

2

Rx for jia

Mtx bc have longest safety record w it and dosing is q week

Second line tnfa inhibitor

3

Name tnf alpha inhibitor

Infliximab
Adilibumab (humira)

4

Apmppe
Unilat or bilater?

Following viral illness--> Bilat bc its an autoimmune attack of choriocapillaris--> infarcts rpe
Generally good prognosis

5

Mutton fat KPs aggregates of what type of cell?

macrophages

6

can pars planitis cause vh and if so how?

yes.
vasculitis-->neo-->vh

7

Whats a bad compliaction of ra?

Scleromalacia perforans

8

what type of rd do you get in pars planitis?

rrd or trd from vasculitis and contraction of neo

9

whats a synonym for C-ANCA?

anti-proteinase 3

10

what are the main SE of cyclosporine and whats the mechanism?

T cell inhibitor
HTN and renal dz

11

when psoriatic arthritis develops wo the artritis part, how does it present differently in the eye?

bilateral
older pt
requires oral NSAIDS

12

If you are on cyclophosphamide, your chance of leukemia is 13x higher if you have what underlying blood disorder?

polycythemia rubra vera

13

MTX mech and SE

folate analogue
GI upset, hepatotoxicity

14

Myopentolate mofetil, brand name, mech of axn and SE

cellcept
inhibits Purine synthesis
diarrhea, GI ulceration

15

what kind of bug is H flu?

gram neg coccus

16

what bug may be responsible for fuchs heterochromic iridocyclitis?

rubella or CMV

17

what kind of bug is bartonella?

gram negative rod

18

besides being bad in MS, what other bad thing can infliximab do?

cause someone to develop lupus and become ana+

19

whats the best treatment for serpiginous, whats the second option if pt is young?

1) cyclophosphamide is best but cant use it If pt wants to have kids
alternative is prednisone, cyclosporine and azathioprine

20

whats the term for how the eye responds to a pathogen in a subdued way?

ACAID- anterior chamber associated immune deviation

21

whats the role of fas ligand in the eye?

fas ligand- the eyes have it!
helps dampen the immune response

22

whats a sysnonym of reactive arthritis?

reiters

23

whats circinate balanitis?

penis rash around head of penis associated with reiters

24

whatst the kveim test?

skin test for sarcoid in which ground up spleen is injected into pt and see if have granulomatous reaction

25

what type of immune rxn is ocp?

type 2- ab DIRECTLY against surface

26

heel spurs are a sign of what HLA B27 dz?

reactive arthritis (reiters)

27

bony destruction of the orbital rim

Langerhans histocytosis

28

kid w unilateral pig changes, pale nerve. UNILATERAL what could it be

DUSN

29

what causes loss of vision in congenital rubella?

cataracts and microphthalmos

30

pt with apmppe comes in with neuropathy- what should you do next?

mra!
apmppee is associated with cerebral vasculitis

31

what are the clues that an anterior uveitis might be viral?

iris atrophy
stellate KP not confined to vogts triangle

32

why cant you keep kids on steroids long?

growth retardation
premature closure of epithysis

33

how does relapsing polychondritis present

scleritis and inflammation of CARTILEDGE
ear tips, nose tip and joint pain

34

name some sequelae of pars planitis

CME
RRD
VH
Glaucoma

35

what protein is expressed at the bow region of the lens as it is proliferating?

major intrinsic protein (MIP)

36

whats the prophylaxis for mai?

rifabutin

37

whats the prophlaxis for pcp?

bactrim

38

for uveitic cataract if acrylic is not available, whats the next best choice?

heparin coated pmma

39

leptospirosis can give false positive of what test?

rpr

40

pt with lupus has brvo, they are at risk for what?

seizures (other cns stuff)

41

kid with jia and band k with uncontrolled iop, whats the definitive surg procedure?

tube

42

how does indomethacin work?

blocks cox

43

what do corticosteroids block?

phospholipase a2

44

besides rifabutin and cidofovir which drugs can cause uveitis?

metipranolol
bisphospinates (eg alendronate)

45

which of the seronehative spondyloarthro[athies is MOST closely ass w HLAB27

ankylosing spondylitis

others:
chrons
psoriatic artiritis
reiters

46

cysticercosis how to treat?

if actual cysts in retina- surgery
no cysts- thiobendazole

47

most common SE of cyclophosphomide

hemorrhagic cystitis

48

kids w sarcoid- what do they get more and wht do they get less?

erythema nodosum MORE
rash- MORE
lung involvemet - LESS

49

list the steroid drops from strongest to weakest

dex
PF= pred sodium phosphate
FML
Rimexolone

50

when is a pt w chrons likely hlab27 +, when are they most likely -?

present w scleritis- likely -
present w acute iritis likely + and will get back pain