Uveitis Flashcards

1
Q

Anatomical classification of uveitis

A

Anterior (iris+ pars plicata) iridocyclitis
Intermediate (para plana) para planitis
Posterior (choroiditis)
Panuveitis (all 3 parts)

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2
Q

Pathological classification of uveitis

A

Granulomatous and non-granulomatous

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3
Q

D shaped pupil in

A

Iridocyclitis

Due to disinsertion of iris due to weakening of roof of iris

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4
Q

Anterior uveitis clinical features

A
Pain 
Redness
Photophobia 
Blepharospasm
Discharge (watery)
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5
Q

Examination findings in anterior uveitis

Just the names briefly

A
Keratin precipitates 
Aqueous cells
Aqueous flare
Muddy iris 
Bussaca and koeppe’s nodules 
Miosis
Post synechae - secclusio and occlusio pupillae
Festooned shaped pupil 
Peripheral anterior synechae 

Iris bombe

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6
Q

What is arlt’s triangle

A

KPs are maximum in lower part of cornea

Due to convection current in aqueous humour

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7
Q

Why does miosis happen in uveitis

A

Due to release of toxins from inflamed tissue

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8
Q

What kind of pupil in angle closure glaucoma

A

Mid dilated pupil

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9
Q

Uveitis pupil shape

A

Constricted pupil

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10
Q

TOC of anterior uveitis

A

Topical steroids

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11
Q

Role of cyclopegics in anterior uveitis

A

Relieves pain and gives rest to the inflamed tissue
Prevents posterior synechae
Break posterior synechae
Relieves spasm (better blood supply and better healing,gives rest to ciliary muscles)

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12
Q

Which drug is ONLY a mydriatic

A

Phenylephrine

Active mydriasis

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13
Q

Strongest mydriatic

A

Atropine

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14
Q

Luminate program

A

Non-steroidal treatment of uveitis

Voclosporin

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15
Q

Intermediate uveitis

A

Inflammation of vitreous and peripheral retina along with para plana

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16
Q

Etiology of intermediate uveitis

A

Idiopathic (more than 70%)
Infective – TB, Leprosy, syphilis
Non-infective-sarcoidosis,Multiple sclerosis

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17
Q

Clinical features of intermediate uveitis

A

Blurred vision

Painless floaters

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18
Q

Examination findings of Intermediate uveitis

A
Decreased visual acuity
Retrolental flare
few KP
Snowballs
Snow banking – fibro vascular and exudative plaque (pathognomic)
Periphlebitis (hallmark)
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19
Q

Most complication of pars planitis

A

Cystoid macular edema

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20
Q

Step ladder approach for intermediate uveitis

A

Local steroids
Systemic steroids
Immunosuppressive drugs
Para plana vitrectony

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21
Q

Posterior uveitis features

A
Choroiditis-round yellow patches 
Vitritis-haziness and flare 
Papillitis-inflammatory optic neuritis
CME
Retinal edema
Periphlebitis
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22
Q

Some causes of non-granulomatous anterior uveitis

A

Ankylosis spondylitis
Psoriatic arthritis
Reuter’s syndrome
JRA-juvenile rheumatoid arthritis

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23
Q

Reiter’s syndrome

A

Arthritis
Conjunctivitis
Urethritis

24
Q

Still’s disease

A

Systemic onset JRA (16 yrs)

25
What is white uveitis
Atypical anterior uveitis (5 features of uveitis absent) | Occurs in early onset pauciarticular seronegative JRA associated with uveitis
26
Complications of JRA
Complicated cataract Secondary glaucoma Band shaped keratopathy
27
Candle wax dripping present in
Venous sheathing | Occurs in sarcoidosis
28
Ocular features of sarcoidosis
Sarcoidosis nodules (episclera/sclera) Interstitial keratitis Band shaped keratopathy Granulomatous panuveitis
29
What is Behçet’s disease
Obliterative vasculitis due to circulating immune complexes
30
Behçet’s disease genetic predisposition
HLA B5 | HLA B51
31
Transient hypopion syndrome seen in
Behçet’s disease | Non-granulomatous anterior and posterior uveitis
32
Eeles disease also known as
Periphlebitis retinae
33
Clinical features of eales disease
``` (Hypersensitivity reaction of TB antigen) Diminution of vision/floaters Recurrent vitreous haemorrhage Venous sheathing (Non-granulomatous posterior uveitis) ```
34
Management of eale’s disease
ATT management of vitreous haemorrhage Partial-postural management (propped up position) Total-pars plana vitrectomy (Non-granulomatous posterior uveitis)
35
MC ocular feature in HIV
HIV induced microangiopathy - haemorrhage - micro aneurysm - cotton wool spots
36
MC opportunistic infection
CMV retinitis (Sauce and cheese retinopathy) (Pizza)
37
Other opportunistic infections and what do they cause
Toxoplasmosis Pneumocystis carinii ^^ choroiditis Herpes zoster ^^ acute retinal necrosis
38
HAART therapy | MC ocular side effect
Immune recovery uveitis | Non-granulomatous/posterior uveitis
39
Headlight in fog appearance
Toxoplasmosis
40
Treatment of toxoplasmosis
Clindamycin
41
Syphilis fundus findings
Salt and pepper fundus (diffuse chorioretinitis) | Juxtapapillary choroiditis
42
TB ocular manifestation
Granulomatous panuveitis MC allergic manifestation of TB-phlyctenular keratoconjunctivitis MC ocular feature of TB-uveitis
43
VKH syndrome (vogt koyanagi harada)
``` Granulomatous panuveitis + systemic feature (Encephalitis Vestibular dysfunction Tinnitus Alopecia Poliosis Vitiligo) ```
44
Sympathetic ophthalmitis
Perforating injury in one eye(exciting eye) causing uveitis in the other eye (sympathising eye)
45
Etiology of sympathetic ophthalmitis
Autoimmune reaction towards uveal tissue
46
Clinical features of sympathetic ophthalmitis
``` Granulomatous panuveitis Dalen Fuch nodules Retrolental flare Decreased accommodation Photophobia ```
47
Where is dalen fuch norules present
Bruchs membrane
48
First sign on sympathetic ophthalmitis
Retrolental flare
49
First symptom of sympathetic ophthalmitis
Decreased accommodation | Photophobia
50
What is the dangerous area of eye
Ciliary body | Any trauma to CB is a big risk of sympathetic ophthalmitis
51
Fuch’s heterochromic cyclitis type of uveitis + other features
``` Atypical anterior uveitis Heterochtomia iridis (involved eye-hypochromic) ```
52
Type of uveitis in fuch’s heterochromic cyclitis
Non-granulomatous anterior uveitis
53
Examination findings in fuch’s heterochromic cyclitis
Rubeosis iridis Stellate KP Heterochromia iridis
54
Complications of fuch’s heterochromic cyclitis
Complicated cataract | Secondary glaucoma
55
Amslers sign
Present in fuch’s heterochromic uveitis | Blood in anterior chamber on paracentesis Due to rubeosis iridis at angle of AC
56
Type of uveitis and TOC of onchocerciasis
Non-granulomatous ant/post | TOC-Ivermectin
57
Opthalmia nodosum
Intense granulomatous inflammation | Caterpillar hair in the eye