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Flashcards in UW 9 Deck (17)
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1
Q

Ovarian tumors and markers

A

GEDECE

Granulosa: Inhibin (precusios puberty or breast enlargement and vaginal bleeding in peri/post menopausal

Epithelial: CA-125

Dysgerminoma: LDH +/- B-hCG. Adolescents. Fried egg

Embryonal: AFP and B-hCG (very agressive, young children)

Choriocarcinoma: B-hCG.

Endodermal sinius/yolk: AFP (very rare, seen in adolescents)

2
Q

Light criteria for pleural efusion

A

Determine if pleural fluid is exudative by meeting at least one of Light’s criteria:

Pleural fluid protein / Serum protein >0.5
Pleural fluid LDH / Serum LDH >0.6
Pleural fluid LDH > 2/3 * Serum LDH Upper Limit of Normal

A quick estimate would be if proteins or LDH are over half of serum value

pH:
Transudate: 7.4-7.55
Exudate: 7.30 - 7.45

3
Q

Management of TTP

A
Plasma exchange (removes patient plasma ans replaces it with donor plasma, also remove antibodies against ADAMTS 13 
glucorticoids, rituximab
4
Q

Post transplant infections

A

<1month: bacterial infection related to operation, wound infection

1-6 months: opportunistic infections en the setting of high dose immunosopresants. Aspergillus, CMV, Mycobacterium

> 6 months: communiti aquire infections at a higher rate then regular people

5
Q

Amoxicylin and EBV

A

maculopapular rash 24 hrs after taking medication in the setting of mononucleosis type illnes

6
Q

Management of mild drug hypersensitivity reaction

A

Type 1 hypersensitivity
IgE mediated
Trear with antihistamines

7
Q

Pain control in patients with opioid addictions

A

Severe pain can be treated with opioids. Follow up carefully to watch out for relapse

8
Q

Normal duration of QT

A

<100msec (<0.1seg)

9
Q

TCAs overdose

A

seizure, coma, cardiotoxicity (QT >100), hyperpirexia, respiratory depresion with dilated pupils (vs. opiods, miosis )

10
Q

Role of Ca gluconate in hyperkalemia

A

Stabilize membrane. It DOES NOT lower potasium

11
Q

Hyperkalemia treatment

A

C BIG K
Calcium gluconate
Beta 2 agosnist (not in MI/angina patients). Bicarbonate
Insuline+glucose

12
Q

Conditions associated with autism (3)

A

Rett sd
Tuberous sclerosis
Fragile X

13
Q

Sings and symptoms of peripheral artery aneurysm

A

Pulsatile mass below de inguinal ligament
Thigh pain do to nerve compression

2nd most common peripheral aneurysm after popliteal

14
Q

NSAIDs use during 1st trimesters

A

Gastroschisis

15
Q

Hypercalcemia mechanism in granulomatosis

A

increased 1a-hydroxylase activity causes incresed production of 1,25 vitamin D.

Hypercalciuria more common than hypercalcemia in sarcoidosis

16
Q

Triad presentation of Henoch-Schonlein purpura

A

Palpable purpura, arthralgias and abdominal pain + ig neprhopathy

17
Q

Differences between TTP and Henoch-Sholen purpura

A

Henoch sholen: normal labs

TTP: low platelets. Purpura is not gravity/pressure dependant (Buttocks)