UW 19 Flashcards by Gaby Matamoros

Acute intermittent porphyria symptoms

Painful abdomen
Port-wine urine
Precipitated: medications, stress
Polyneuropathy
Psychiatric symptoms

How well did you know this?

Not at all

Perfectly

Peutz-Jegherz sd

GI hemartomatous polyps

1-5mm perioral mucocutaneous pigmented macules

How well did you know this?

Not at all

Perfectly

Blood findings of defective prosthetic valves

Hemolytic anemia and thrombocytopenia can be found to due to mechanical damage

How well did you know this?

Not at all

Perfectly

Rheumatoid arthritis treatment

NSAIDs (for acute pain/crisis)

First line:
Methotrexate

Others
CD 20 inhibitor: leuflonide
TNF inhibitor: rituximab

How well did you know this?

Not at all

Perfectly

MOA of Rituximap

TNF inhibitor

How well did you know this?

Not at all

Perfectly

Treatment for neuroleptic malignant sydrome

Dantroline or bromocriptine

How well did you know this?

Not at all

Perfectly

Treatment of Serotonin sd

Cyproheptadine (antihistamine: blocks serotonin production)

Benzos: for altered mental status

How well did you know this?

Not at all

Perfectly

Treatment of Bullous penphigoid vs. Pephigus vulgaris

Bullous penphigoid: topical corticosteroids (eg, clobetasol)

Pephigus bulgaris: systemic steroids +/- azathriopine, mycophenolate, IVGI, rituximab

How well did you know this?

Not at all

Perfectly

Wilms Tumor

Embryonic glomerular structure.
Most common renal malignancy. 2-5 yoa

Asymptomatic
Palpable mass
+/- Hematuria, hypertension, absominal pain

WARG
Wilms tumor
Aniridia
Retardation
Genitourinary malformations

How well did you know this?

Not at all

Perfectly

Neuroblastoma

Adrenal medulla tumor
Kids <2yoa
Tumor crosses mid line (vs. pheochromocytoma)
Periorbital echymosis (raccoon eyes)
Opsoclonus-myoclonus (dancing eyes and feet)

Diagnosis: catecholamine metabolites in blood, n-myc oncogene, small round blue cells on hystology

Dxx: Wills tumor
Hematuria, hypertension, WT-1 chromosome 11

How well did you know this?

Not at all

Perfectly

Indication for systemic atb therapy of anal abscess after drainage

Systemic illness (fever) or cellulitis

2. Diabetes or immunosupresion

How well did you know this?

Not at all

Perfectly

Severe retinopathy of prematurity

Retinal detachment in infants born <30 weeks gestation

Causes leucokoria

How well did you know this?

Not at all

Perfectly

Retinoblastoma red flags

White reflex
Strabismus
Nystagmus

How well did you know this?

Not at all

Perfectly

ECG findings of pericardial efusion

Electrical alternans (QRS variation of amplitud)

How well did you know this?

Not at all

Perfectly

Wolf-Parkinson-White treatment

Procainamide
Amiodarone
Ibutilde

(B-blockers and CCC are contraindicated)

How well did you know this?

Not at all

Perfectly

Uterine atony management

Bimanual massage
High dose oxytocin, misoprostol
Trenaxemic acid
Carbapost (contraindicated in asthmatic patients), metergine (if not hypertensive)
Intrauterine balloon
Surgery

How well did you know this?

Not at all

Perfectly

Dxx of foot pain

Stress fracture:
Arthritis
Morton neuroma
Tarsal tunnel sd

Stress fracture: localized pain, seen specially in runners, dorsal surface, 2nd, 3rd and 4th metatarsal

Arthritis: pain in the joints, not localized

Morton neuroma: pain between 3rd and 4th toe. Plantar surface, clicking sound on palpation

Tarsal tunnel sd: after anckle fractures. Burning sensation, aching and numbness on plantar surface

How well did you know this?

Not at all

Perfectly

DIfference between intraparenchymal vs. subarachnoid hemorrhage

Intraparenchymal: focalization symptoms that worsen within a few hours. Blood is in the brain. (If hypertension: basal ganglia, av malformation in kids)

Subarachnoid: sudden headache without focalization. Blood is in between the sulci.

How well did you know this?

Not at all

Perfectly

Patophysiology of hyper IgM sd

CD 40 ligand on T cells deficiency… prevents Ig class switching because it cant bind to CD40 receptor on B cells

How well did you know this?

Not at all

Perfectly

CT findings of High grade astrocytoma

Study These Flashcards

High grade astrocytoma = glioblastoma multiforme

Butterfly appearance with central necrosis. Serpentiginous, well defined enhancing

Vs. abseces: enhancing is thicker and diffuse

Systemic symptos of anorexia

Study These Flashcards

Hypotension, bradycardia, hypothermia
Gastroparesis, constipation
Cardia atrophy, arryhtmias

Systemic symptos of anorexia

Study These Flashcards

Hypotension, bradycardia, hypothermia
Gastroparesis, constipation
Cardia atrophy, arryhtmias

vs. hypothyrioidsm: diastolic hypertension

Alvarado score for apendicitis

Study These Flashcards

1 point each
RLQ migratory pain
Fever
Anorexia
Nausea and vomiting
RLQ rebound tenderness

2 points each
RLQ tenderness
Leukocytosis (>10.000)

Patient with 1 amenorrhe, 2nd sexual characters developed.

Study These Flashcards

Amenorrhea normal <15 yoa if secondary characters are developing

Women have a rapid growth spurt right before menarche. If patient is growing “fast” then reassure

Universal screening for pregnant patients

HIV Hep B Syphilis Chlamydia

Language disorder

Deficit in understanding and/or producing language Presentation: Limited vocabulary Inadecuate structure Difficulty ussing language to communicate, explain cocepts, create stories Other symptoms: Frustration, look for attention in other ways (biting, hitting,)

Concussion symptoms

Headache (predominant symptom) can worsen with sounds, concentrating, eye movements Irritability, sleep disturbances

What do you need to remember about parvo19 in adults

Patients with kid contacts are at risk of viral arthitis

Fibular neuropathy

Foot drop Impaired dorsiflexion Preserve plantar flexion (walk on toes) Sensory deficit on lat aspect of dorsal foot an shin

Aortic dissection and hoarness

Expansion of the intima compresess the laringial nerve

Diagnosis of aortic disection

CT angiography (for stable patients) TEE if not stable

Diagnosis of Adrenal insuficiency

Consytropin stimulation test (ACTH analogue) Normal response: rise in cortisol No rise in cortisol = AI

Adrenal insuficiency labs

Hyperkalemia, hyponatremia Eosinophilia Normal to low glucose Low cortisol, high ACTH

AD Polycystic Kidney disease Presentation and extra renal features

Asymptomatic until 30-40 Flank pain, palpable mass Hematuria Others: polyuria (cant cocnentrate urine), hypertension, progresive renal dysfunction) ``` Extrarenal manifestations: Brain aneurism Colonic diverticulos Hepatic/pancreatic cyst Mitral valve prolapse, aortic regurge ```

Location of appendicitis in pregnant women

RUQ

Auscultation findings in pulmonary contusion

Rales or decrease breath sounds do to pulmonary edema (from hemorrhage that is later worsen by IV fluids)

Time frame of pulmoary contusion vs fat embolism

Pulmonary contusion: <24hrs Fat embolism: 12-72 hrs

Triad of gonoccocal arthritis

Tenosinovitis migratory Arthritis Maculo/papular discharge

TRALI

Non cardiogenic pulmonary edema Pulmonary infiltrates Within 6 hrs

Acute hemolytic reaction

``` <1hr Fever, flank pain, hemoglobinuria, pain at catheter insertion site Low BP, tachycardia Normal O2 sat Positive coombs ``` Management: Aggressive IV fluids

Management con complicated diverticulitis

Abscess <3cm: ATB Abscess >3cm: CTpercutaneous draingage If no improvement after a few days... surgery

Medications associated with neurotoxicity

Calcineurin inhibitors Cyclosporin and tracolimus

Anti Jo antibodies

Polymyositis/dermato

Treatment of Bells palsy

Prednisone

Management of edema secondary to Calcium channel blockers

ACEI

When to administer Hep B vaccine in a premature baby

When it >2kg

Contraindication for faxtor Xa inhibitor

Renal failure | DVT/PE due to malignancy

Drugs related to Folate deficiency

Phenytoin Methotrexate Pyrimethamine TMP-SMX

Indication for IECAs in diabetic patient

Hypertensive patien Albumin/creatine ratio >30

UW 19 Flashcards

(49 cards)