Uworld 3 Flashcards

1
Q

blood type antibodies

A

IgM

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2
Q

PSGN what deposits?

A

IgG, IgM, C3

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3
Q

Schistosomiasis- from what animal?

A

snail

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4
Q

majority of overdoses from what?

A

opiates

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5
Q

AST increase w/out accompanying ALT

A

suggests MI

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6
Q

proliferative stimuli for atherosclerotic plaque?

A

platelets

PDGF

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7
Q

zinc fingers- what hormones?

A

lipid soluble (transcription factors)

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8
Q

loss of 2,3 BPG binding –>

A

increased O2 affinity like fetal Hg

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9
Q

Airway epithelium transition. Last thing to disappear?

A

cilia

need to get mucous out

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10
Q

sickle cell disease osteomyelitis from what?

A

think salmonella
capsule
resists opsonization

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11
Q

dihydropyridines

A

end in -ine
increase peripheral vasodilation
rx HTN w/o cardiac effects

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12
Q

pneumonia in alcoholic

A

klebsiella

use ceftriaxone

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13
Q

prognosis in melanoma is strongly determined by

A

depth of the lesion

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14
Q

test to determine Rh incompatibility

A

indirect Coombs test to detect IgG antibody

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15
Q

t(9,22)

A

BCR-ABL
Philadelphia chromosome

CML

increased neutrophils, metamyelocytes (immature neutrophils) and basophilia

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16
Q

Rathke pouch (anterior pituitary) from what embryologic layer?

A

surface ectoderm

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17
Q

budding yeast that forms germ tubes at 37 degrees?

A

candida

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18
Q

influenza viruses = orthomyxovirus, how create new strains?

A

genetic reassortment of RNA segments

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19
Q

Portocaval anastamoses

A

Left gastric –> esophageal
Superior rectal –> middle and inferior rectal
paraumbilical–> superficial and inferior epigastric

20
Q

parotid gland tumor –>

A

facial droop

21
Q

digoxin toxicity

A

Color Vision Changes *

arrhythmias

anorexia, nausea, vomiting, pain
fatigue, confusion, weakness

22
Q

vWF binds to what?

A

collagen

23
Q

sickle cell protein change

A

valine for glutamic acid

24
Q

pull undescended testicle through what?

A

external oblique aponeurosis

25
Q

malignant otitis externa in elderly diabetics

A

pseudo aeruginosa
non lactose fermenting
ox pos
gram neg rod

26
Q

caudal regression syndrome

A

agenesis of sacrum/ lumbar

poorly controlled maternal diabetes

27
Q

arginine- what cycle

A

urea

28
Q

diet of carbs and proteins. What increases to inhibit beta oxidation?

A

malonyl CoA inhibits carnitine acyl transferase

29
Q

sign of insulin resistance

A

increased waist circumference

30
Q

treat specific phobia (elevators)

A

behavioral

31
Q

centriacinar emphysema pathogenesis

A

macrophages and neutrophils release proteases that degrade ECM

32
Q

candida causes include

A

tobacco

33
Q

what makes elastase in lungs?

A

alveolar macrophages

34
Q

what makes secretin?

A

S cells of duodenum

35
Q

absence of vas def- what condition?

A

cystic fibrosis

36
Q

highest O2 content of fetal circ

A

umbilical vein –> liver–> IVC

37
Q

collagen hydroxylation (vit C) happens where?

A

RER

38
Q

what keeps strep from phagocytosis?

A

protein M

39
Q

failed lateral fusion of paramesonephric ducts (= mullerian ducts) –>

A

bicornate uterus

mesonephric ducts don’t fuse

40
Q

west nile

A

febrile, rash, encephalitis, flaccid paralysis

RNA flavivirus

41
Q

aldolase B defish, remove what from diet?

A

sucrose

42
Q

osteocytes connected to ea other by

A

gap jxns

43
Q

H flu grows well w/ staph aureus why?

A

provides NAD+

44
Q

obesity lung disease

A

restrictive

45
Q

turner syndrome infertility

A

ovarian failure

use IVF

46
Q

Rx for preggo with DVT

A

enoxaparin

LMWHs don’t cross placenta