Flashcards in Vaccines Deck (12):
What is an adjuvant?
compound that increases the immunogenicity of an antigen
What is the most common adjuvant in vaccines?
aluminum salt Alum
What is a live attenuated virus?
a weakened virus that can replicate to a limited extent
Would you give MMR (measles, mumps, rubella) vaccine to a patient with a immunodeficiency disorder?
NO, can't fight it off
What is the difference between DPT and DTaP vaccines?
DPT is diptheria, tetanus and whole, killed pertussis antigen and DTaP replaced pertussis bacteria with acellular components (pertussis toxoid and alum)
For what patients you just Tdap vaccine? What do the lower cases mean?
in adults and adolescents, means reduced concentration
Why did the switch from DPT to DTaP occur?
killed pertussis was a very strong adjuvant that induced a strong innate immune response leading to severe fever in some cases
What type of vaccine is MMR?
live attenuated vaccine
What is RIG?
rabies immune globulin, passive immunization
What is HDCV? PCECV?
human diploid cell rabies vaccine, purified chick embryo cell vaccine
What do you give for someone previously immunized to rabies?
HDCV or PCECV on day 0 and 3