Vaccines Flashcards Preview

Immunology > Vaccines > Flashcards

Flashcards in Vaccines Deck (12):
1

What is an adjuvant?

compound that increases the immunogenicity of an antigen

2

What is the most common adjuvant in vaccines?

aluminum salt Alum

3

What is a live attenuated virus?

a weakened virus that can replicate to a limited extent

4

Would you give MMR (measles, mumps, rubella) vaccine to a patient with a immunodeficiency disorder?

NO, can't fight it off

5

What is the difference between DPT and DTaP vaccines?

DPT is diptheria, tetanus and whole, killed pertussis antigen and DTaP replaced pertussis bacteria with acellular components (pertussis toxoid and alum)

6

For what patients you just Tdap vaccine? What do the lower cases mean?

in adults and adolescents, means reduced concentration

7

Why did the switch from DPT to DTaP occur?

killed pertussis was a very strong adjuvant that induced a strong innate immune response leading to severe fever in some cases

8

What type of vaccine is MMR?

live attenuated vaccine

9

What is RIG?

rabies immune globulin, passive immunization

10

What is HDCV? PCECV?

human diploid cell rabies vaccine, purified chick embryo cell vaccine

11

What do you give for someone previously immunized to rabies?

HDCV or PCECV on day 0 and 3

12

What do you give for someone not immunized to rabies?

RIG near wound, HDCV or PCECV at different site on day 0,3,7,14