Vaginitis Flashcards

(45 cards)

1
Q

Describe normal vaginal secretions.

A

slight or no odour
clear to white (consistency of egg whites)
viscous and homogeneous
1-4ml secreted daily
acidic (pH 3.8-4.2)
5-10 bacterial species that can usually be cultured
-lactobacillus predominate

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2
Q

What can impact secretions throughout the cycle?

A

stress
diet
medications
sexual activity

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3
Q

What are all the different colours of vaginal discharge? What do they mean?

A

white: healthy discharge, yeast infection
clear: healthy discharge, pregnancy, ovulation, hormonal
imbalances
gray: bacterial vaginosis
pink: cervical bleeding, vaginal irritation, implantation bleeding
red: menstruation, cervical infection, cervical polyp,
endometrial or cervical cancer
yellow-green: sexually transmitted infection

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4
Q

In regards to colour-coded vaginal discharge, what are some variations to keep in mind?

A

cycle
lifestyle
environment
each individual serves as their own best baseline

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5
Q

What is vaginitis?

A

inflammation of the vulva (outside), vagina (inside) or both
-with or without vaginal discharge

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6
Q

What are the causes of vaginitis?

A

majority of the time due to an infection:
-bacterial vaginosis, vulvovaginal candidiasis, trichomoniasis,
or STI
may also be noninfectious:
-atrophy during peri-menopause
-physiologic (change in normal flora, mid-cycle cervical fluid)
-retention of foreign body (tampon)
-allergy

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7
Q

True or false: viral genital infections generally cause vaginitis

A

false

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8
Q

What are the four types of vaginitis?

A

vulvovaginal candidiasis
bacterial vaginosis
atrophy
trichomoniasis

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9
Q

Describe vulvovaginal candidiasis.

A

severe pruritis of vulva and vaginal areas
stinging/burning
“cottage cheese” discharge
odourless
pH<4.5

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10
Q

Describe bacterial vaginosis.

A

fishy odour
creamy discharge (grey)
pH 5-6

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11
Q

Describe atrophy.

A

vaginal discharge
spotting
soreness and burning
pH 7

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12
Q

Describe trichomoniasis.

A

frothy wet discharge
pruritis possible
malodourous
pH>6

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13
Q

Which types of vaginitis do we refer to an MD?

A

bacterial vaginosis
trichomoniasis

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14
Q

List off things that can alter the normal vaginal flora.

A

puberty
menstruation
estrogen or OCP therapy
pregnancy
post-menopause
antibiotics
vaginal surgery

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15
Q

What are risk factors for infection?

A

uncontrolled diabetes
broad spectrum antibiotics
immunosuppression
medications
diet
stress
pregnancy
menses
chemical irritants
synthetic, non-breathable undergarments and clothing

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16
Q

What is the pathogenesis of vaginitis?

A

an overgrowth of yeast cells Candida albicans that is already present in vulvovaginal area
the overgrowth can be initiated by risk factors

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17
Q

Differentiate between complicated and uncomplicated vulvovaginal candidiasis.

A

uncomplicated: sporadic, easily treated, caused by Candida
albicans
complicated: recurrent, severe disease, not caused by C.
albicans, or abnormal host factors

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18
Q

When does vulvovaginal candidiasis peak in women?

A

30-40 years of age
risk increases in 20s and is rare before puberty

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19
Q

What are the signs and symptoms of vulvovaginal candidiasis?

A

itching, soreness and/or burning discomfort
dysuria
dyspareunia
heavy white vaginal discharge (odourless)
bright red rash affecting inner and outer parts of the vulva

20
Q

When do we refer vulvovaginal candidiasis to a doctor?

A

symptoms for 1st time
discharge has colour, coloured or profuse
presence of other symptoms
pregnant
pre-pubertal (<12)
diabetes or other underlying chronic illness
recurrence within 2 months
immunosuppressed
at risk of STI (unprotected sex, multiple partners)

21
Q

How does the vaginal infection screening test work?

A

it tests pH, higher pH turns green/blue meaning it is likely not a yeast infection
bacterial vaginosis and trichomoniasis show elevated pH

22
Q

True or false: there are no long-term consequences of vulvovaginal candidiasis to fertility that we know of

23
Q

True or false: bacterial vaginosis has no associated increased risk of getting an STI

A

false
risk of getting an STI increases and passing an STI

24
Q

When is OTC treatment appropriate for vulvovaginal candidiasis?

A

uncomplicated infection
VVC previously diagnosed

25
Describe clotrimazole treatment for VVC.
Oral -500mg vaginal tab x 1 dose -or 200mg vaginal tablet x 3 nights 1% topical cream -1 applicatorful of vaginal cream PV at bedtime x 7 days -2% cream x 3 days, 10% cream x 1 day -apply externally to vulva daily-bid prn for itch
26
Describe miconazole treatment for VVC.
Oral -100mg vaginal ovule HS for 7 days -or 400mg HS x 3 nights -or 1200mg HS x 1 dose 2% topical cream -1 applicatorful of vaginal cream PV at bedtime x 7 days -4% cream x 3 days -apply externally to vulva daily-bid prn
27
What are some side effects of miconzaole and clotrimazole?
very uncommon, maybe an allergy or irritation
28
Describe oral fluconazole treatment.
1 dose 150mg do not use in girls <12 years can be used with azole topical external cream results within 3-7 days
29
What are side effects of oral fluconazole treatment?
nausea abdominal pain headaches diarrhea dyspepsia
30
What must you do if you recommend oral fluconazole?
check for drug interactions
31
Describe boric acid treatment.
600mg in 1 gelatin capsule 1 capsule inserted PV OD or BID x 14-28 days not to be taken orally
32
What can a patient expect with treatment of vaginal yeast infections?
adverse effects are uncommon allergies are possible irritation can be dose related successful therapy will resolve within 7 days short course therapy does not achieve results faster than long course therapy
33
What is some information to tell a patient about treatment of vaginal yeast infections?
how to use, duration, side effects continue until course finished nighttime is a good time to use condom or diapragm efficacy reduced continue through menstrual period (do not use tampons) generally arent sexually transmitted to partner intercourse not recommended during therapy
34
What is a natural treatment for vaginal yeast infections?
plain yogurt with no sweeteners
35
How can vaginitis be prevented?
control risk factors general hygiene probiotics
36
What are prescription treatments for vaginal yeast infections? When are these products used?
terconazole 0.4% cream PV x 7 days topical nystatin -used in suspected resistant infections, pregnant women, drug coverage
37
When do we suspect that vaginal yeast infections are recurrent?
4 or more infections within a year the infections have caused symptoms infections were not related to the use of antibiotics
38
What is the treatment for recurrent vaginal yeast infections?
fluconazole 150mg PO once every 3 days for 3 doses boric acid 300-600mg cap placed in the vagina OD for 14 days
39
What are the treatments of vaginal yeast infections in pregnancy?
oral fluconazole (but recommended to avoid) topical or vaginal azole for 7 days topical nystatin
40
What is vaginal douching?
instilling fluid into the vagina in a flushing manner not a necessary part of vaginal cleanliness and can be harmful warm water, vinegar and water, sodium bicarbonate and water, various commercial products
41
What are the disadvantages of vaginal douching?
disruption of normal flora vaginal irritation possibly increase the risk of ascending infection
42
What are the treatments for bacterial vaginosis?
metronidazole 500mg PO BID for 7 days metronidazole gel 0.75%, one applicator (5g) OD vaginally for 5 days clindamycin cream 2%, one applicator (5g) OD vaginally for 7 days CanesBalance
43
What are the signs and symptoms of trichomoniasis?
malodourous discharge is purulent (thin/frothy, green/yellow) burning dyspepsia frequent urination dyspareunia
44
What are the treatments for trichomoniasis?
metronidazole 2g PO in a single dose metronidazole 500mg PO BID for 7 days
45
How long does resolution take with miconazole or clotrimazole treatment for VVC?
7 days even if its the 1 or 3 day treatment