Valvular Disease Flashcards

(67 cards)

1
Q

Symptomatic MS- intervene if MVA is —-

A

1.5 or less

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2
Q

If MVA is less than 1 and pt asymptomatic what to do

A

If valve suitable for BMV-do it . IIb:Otherwise monitor

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3
Q

Severe MS is

A

MVA 1.5 or less- ACC/AHA-2014
Moderate MS is 1.6-2 cm2
Very Severe MS is 1 cm2 or less

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4
Q

Stage B or Progressive MS is MVA of

A

More than 1.5 and pressure half time < 150

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5
Q

ACC/AHA classification of VALVE diseases

A

Stage A-at risk;
B- progressive
C-Asymptomatic
D-Symptomatic

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6
Q

PASP for decisions on MS

A

50 mm Hg

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7
Q

MV replacement indications in MR i.e. The definite indications

A
  1. symptoms+EF>30
  2. Asymptomatic and LVESD at least 40

If in symptomatic pts EF 30 or less a weak recommendation is that Mitral Valve repair can be considered

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8
Q

Role of Afib and PASP in deciding MV surgery

A

Asymptomatic Severe MR with Afib or PASP >50 can consider REPAIR if success high

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9
Q

Mitral valve repair best with–//

Chordal rupture repair best with

A

Posterior leaflet

Posterior chordal rupture

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10
Q

Mitral valve cusp at intervalvular fibrosa

A

A3 cusp

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11
Q

Pml forms — part of annulus

A

5/8

But Total area of Aml and pml are same in systole

The name of commissures come from the papillary muscles - anterolateral and posteromedial

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12
Q

Most commonly fused cusps in Bicuspid Aortic valve

A

Right and left

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13
Q

Difference between rheumatic and degenerative AS in Echo is

A

Degen-near Aortic ring. Rheumatic less involvement near the ring

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14
Q

Effect of ARB or Betablocker in ascending aortopathy of Bicuspid Aortic valve

A

No studies demonstrated benefit.2014 ACC/AHA did not recommend any pharmacologic treatment in the absence of another indication like HTN

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15
Q

When to do Surgery for Aorta in Bicuspid Aortic valve

A
  1. > 5.5 cm at root or Asc Aorta

2. If growth rate >.5cm/year or if surgical risk <4%ie expert centre or families history of dissection consider at 5 cm

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16
Q

VCW in Severe MR

A

0.7 cm or more

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17
Q

0.3cm VCW is mild or mod MR

A

Moderate MR

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18
Q

E velocity in Severe MR

A

More than 1.4 cm/s

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19
Q

E/A ratio in Severe MR

A

2 or more

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20
Q

V wave cut off sign indicates

A

Severe MR in CWD

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21
Q

Surface velocity of PISA is

A

Equal to the chosen Aliasing velocity

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22
Q

Effectiveness of PISA in quantifying MR

A

Moderate accuracy

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23
Q

EROA by PISA eqn

A

2#r 2 x aliasing vel. / peak MV vel

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24
Q

Normal pulmonary venous flow during Doppler

A

Antegrade in both systole and diastole with systole dominant

With slight retrograde flow during atrial syst

In Severe MR-Systolic flow reversal

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25
The mean gradient in MS is above
10 mm Hg
26
Oral penicillin prophylaxis for RHD
Penicillin V 250 mg BD | If allergic..Azithromycin 250 mg OD
27
In the absence of MS E velocity more than------ suggests Severe MR
More than 1.5 m/s
28
BMV during pregnancy is done at
AFTER 20 wks of gestation
29
How to get EROA by PISA
Measure PISA radius Measure MR VTI Machine will give you EROA and Regurgitant volume To calculate RFraction --divide RV by RV + Aortic VTI
30
VCW in Severe AR
MORE than 6 mm
31
How to measure mitral Antero- Postr diameter
In PLAX view
32
Mitral annular dilatation Echo criteria
Mitral AP diameter/ Length of Anterior leaflet in diastole More than 1.3 or When diameter is more than 35
33
The normal decrease in Mitral annular area in systole is
25%
34
Acute rheumatic fever occurs ---wks after GAS infection
2-4 wks
35
Clinical features of ARF( rheumatic fever)
ACCESS- Arthritis, Carditis, Chorea, Erythema marginatum, Subcutaneous nodules
36
Most common manifestation of ARF
Carditis -50-70% | Then Arthritis
37
Penicillin used for ARF prophylaxis
Penicillin G Benzathine ORAL is Penicillin V 250 BD or Azithromycin 250 OD
38
Aortic finding in AR
proximal ABDOMINAL Aorta shows holodiastolic flow reversal in Severe AR
39
Role of M Mode in MVP diagnosis
No role
40
Indications for surgery in Severe AR
1. Symptoms 2. EF< 50% 3. ESD >50mm 4. EDD> 65 mm of low risk. All are independent. Uptodate 2018
41
Mild Aortic stenosis
ASE 2017 Guidelines-2.5 or less is Aortic sclerosis 2.6 is mild Aortic stenosis 3m/s is Moderate or mean of 20 -40 is Moderate 41 Mean is Severe
42
Key parameter to diagnose low gradient normal EF Aortic stenosis
Stroke volume index < 35ml/m2 For low gradient low EF - do DSE
43
Life span of metallic prosthetic valve
20-30 yrs
44
TTK chitra is a
Tilting disc valve
45
Acute Rheumatic fever major criteria in order of frequency
CACSE Carditis, Arthritis, Chorea, Subcutaneous nodules, Erythema marginatum
46
Doppler findings in Rheumatic Valvulitis
MR-2 views, 2 cm in length,peak velocity 3m/s And Pansystolic jet ( All 4 required) AR- same as above but 1 cm length and pan diastolic
47
The Arthritis of ARF lasts for around.....with or without therapy
4 weeks
48
How long you will need NSAIDs for Arthritis treatment
1-2 weeks usually. Sometimes upto 8 weeks
49
CRP And ESR monitoring in ARF treatment
CRP twice weekly then every one to two weeks till normal ESR may stay elevated for upto 2 months after a transient inflammatory stimulus. CRP normalizes over matter of days once inflammation subsided Uptodate 2017
50
No of randomized trials done for TAVR vs surgery b/w 2012 and 2017
5
51
Aortic valve velocity in mild AS
ASE 2017 Guidelines-2.5 or less is Aortic sclerosis | 2.6 is mild Aortic stenosis
52
ESC 2017 recommendation on TAVI - broadly speaking
TAVI for high risk | SAVR for low risk esp younger pts Intermediate risk- bla bla
53
Mean age of TAVI trials as of 2017
80 yrs Can we apply this data to those below 70?
54
——-&——-are more in TAVI than SAVR
Paravalvular leak and need of PPI
55
ESC position on NOAC in MR and Aortic Valve disease
Can give | But contraindicated in MS and Mechanical valves
56
Penicillin used for RHD prophylaxis
Penicillin V 250 mg BD
57
All severe regurgitations have ........shape in CW
Triangular with early peak . Otherwise it’s meso(mid)systolic peak . May not be always. But triangular means severe From Internet
58
Acute Rheumatic Arthritis may need treatment upto ....
8 weeks Most will respond in 1-2 weeks. Then you can try reducing
59
In acute Rheumatic fever If response to Aspirin doesn’t occur in ..... hrs suspect the diagnosis
24-36 hours ( Chorea doesn’t respond)
60
Number of RCTs between 2012 and 2017 on TAVR
5 studies
61
Why TAVI not preferred in younger patients
1. No long term data on durability of TAVI valves 2. Trials were on pts with mean age of 80 3. Paravalvular leak and need of PPI higher with TAVI. ESC 2017
62
NOAC in valvular heart disease
Aortic valve disease and Mitral regurgitation -suffficient data to use. ESC 2017 Not in significant MS
63
Most important risk factor for death and disability after successful correction of valvular lesion
Residual Pulmonary Hypertension
64
Which study showed Sildenafil is not effective in residual PAH in Valvular lesions
2017 SIOVAC trial
65
30 day all cause mortality after TAVI | Also 1 yr mortality rate
1 year- around 20% 30 day around 10%
66
Aortic sclerosis definition
Velocity < 2m/s with thickened Aortic Valve Uptodate -seems to be wrong ASE 2017 Guidelines-2.5 or less is Aortic sclerosis 2.6 is mild Aortic stenosis
67
Best view for VCW of mitral valve
PLAX JACC article 2012