Vasopressin (VP)

Question 1

VP receptors:

Answer 1

V1: G-coupled vasoconstriction (arterial constriction)
V2: Renal collecting duct to reabsorb H2O

Question 2

VP is a ________ hormone?

Answer 2

Posterior Pituitary (ADH)

Question 3

What is VP used for mostly?

Answer 3

To preserve cardiocirculatory homeostasis in pts c/ advanced vasodilatory shock.

Question 4

What happens to Epi and VP in an acidic environment?

Answer 4

Epi loses its effect while VP does not lose its effect

Question 5

Is VP a reasonable alternative to Epi in Tx of cardiac arrest?

Answer 5

Yes, and has less adverse effects than Epi.