** Very High-Yield ** Flashcards Preview

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Flashcards in ** Very High-Yield ** Deck (20):
1

Interaction with this drug requires dose reduction of 6-MP

Allopurinol

2

Antidote for tissue plasminogen activator (t-PA), streptokinase

Aminocaproic acid

3

Cheap wide spectrum antibiotic DOC of otitis media

Amoxicillin

4

Antidote used for organophosphate/anticholinesterase poisoning

Atropine, pralidoxime (2-PAM)

5

Vancomycin MOA

Binds D-Ala-D-Ala on murein monomers and prevent polymerization of the murein monomers

6

ACTH analog used for diagnosis of patients with corticosteroid abnormality

Cosyntropin

7

Agents used in treatment of carcinoid tumor

Cyproheptadine

8

1st generation antihistamine that is highly sedating

Diphendydramine

9

Common SE of spironolactone

Gynecomastia and hyperkalemia

10

MOA of fluoroquinolones

Inhibit DNA gyrase (topoisomerase II) and topoisomerase IV

11

Agent of choice for the treatment of hypothyroidism

Levothyroxine (T4)

12

Drug of choice for tx of pseudomembranous colitis

Metronidazole

13

Agents for reduction of postpartum bleeding

Oxytocin and ergonovine

14

Binds tubulin and prevents the disassembly of microtubules during the M phase of the cell cycle inducing mitotic arrest

Paclitaxel (taxol)

15

Antidote used for heparin toxicity

Protamine Sulfate

16

Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and currently being tested for treatment of breast cancer (Stars study)

Raloxifene

17

Increase bone density, also being tested for breast CA tx.

Raloxifene (SERM-selective estrogen receptor modulator)

18


5HT-1D/1B agonist used for migraine headaches

Sumatriptan, naratriptan, and rizatriptan

19

Anti-estrogen used for estrogen receptor + breast cancer

Tamoxifen

20

5HT-3 antagonist used in chemotherapeutic induced
emesis

Ondansetron, granisetron, dolasetron and palonosetron