VI - Topnotch Pharma Flash Cards - Endocrine Drugs Preview

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Flashcards in VI - Topnotch Pharma Flash Cards - Endocrine Drugs Deck (112)
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1

Recombinant Growth hormone

Somatropin (TOPNOTCH)

2

Increases release of IGF-1 in the liver and carilage, stimulates skeletal muscle growth, amino acid transport, protein synthesis and cell proliferation

Somatropin (TOPNOTCH)

3

Recombinant IGF-1

Mecasermin (TOPNOTCH)

4

Somatostatin analog

Octreotide, Lanreotide (TOPNOTCH)

5

suppresses the release of growth hormones, glucagon, insulin, gastrin, IGF-1, serotonin and gastrointestinal peptides

Octreotide, Lanreotide (TOPNOTCH)

6

For Acromegaly, pituitary adenoma, carcinoid, gastrinoma, glucagonoma, variceal bleeding

Octreotide, Lanreotide (TOPNOTCH)

7

GH receptor antagonist ; For acromegaly

Pegvisomant (TOPNOTCH)

8

Gonadotropin analog (FSH analog) ; For Controlled ovarian hyperstimulation, infertility due to hypogonadism in men

Follitropin alfa, Follitropin beta, Urofollitropin (TOPNOTCH)

9

Gonadotropin analog (LH analog)

For Controlled ovarian hyperstimulation (ovulation induction), hypogonadotripic hypogonadism (TOPNOTCH)

10

SE: Headache, depression, edema, ovarian hyperstimulation syndrome, multiple pregnancies in women, gynecomastia in men

FHS and LH analogs (TOPNOTCH)

11

GnRH analog

Leuprolide, Gonadorelin, Goserelin, Histrelin, Nafarelin, Triptorelin (TOPNOTCH)

12

For Controlled ovarian hyperstimulation, endometriosis, myoma uteri, precocious puberty, postate CA

Leuprolide, Gonadorelin, Goserelin, Histrelin, Nafarelin, Triptorelin (TOPNOTCH)

13

there is exacerbation of symptoms in males with prostate CA and children with precocious puberty during the first few weeks of therapy

GnRH analog (TOPNOTCH)

14

For GnRH analogs: increased LH and FSH secretion with ________ administration , reduced LH and FSH secretion with ________ administration

intermittent ; prolonged continuous (TOPNOTCH)

15

GnRH antagonist

Ganirelix, Cetrorelix, Degarelix (TOPNOTCH)

16

For Controlled ovarian hyperstimulation (prevents premature LH surge), advanced prostate CA

Ganirelix, Cetrorelix, Degarelix (TOPNOTCH)

17

Does NOT cause tumor flare-up whe used for treatment of advanced prostate cancer

Ganirelix, Cetrorelix, Degarelix (TOPNOTCH)

18

_____ is used for prostate CA while _____ prevent LH surge in controlled ovulation

Degarelix ; Ganirelix (TOPNOTCH)

19

Dopamine agonist, partial agonist at dopamine D2 receptors in brain ; For Hyperprolactinemia, Pituitary adenoma, acromegaly, Parkinson's disease

Bromocriptine, Carbegoline (TOPNOTCH)

20

Activates oxytocin receptors stimulates uterine contraction and labor, stimulates mammary glands, lactation and milk let-down

Oxytocin (TOPNOTCH)

21

For Labor induction, labor augmentation, control of uterine hemorrhage post-delivery

Oxytocin (TOPNOTCH)

22

oxytocin antagonist used in preterm labor

ATOSIBAN (TOPNOTCH)

23

ADH agonist, Vasopressin V2 receptor agonist

Desmopressin (TOPNOTCH)

24

For Central DI, Hemphilia A, von Willebrand's disease, Variceal bleeding, primary nocturnal seizures

Desmopressin (TOPNOTCH)

25

SE: Fetal distress, placental abruption, uterine rupture, fluid retention, hyponatremia, heart failure, seizures, hypotension

Oxytocin (TOPNOTCH)

26

ADH antagonist, Antagonist at V1a and V2 receptors

Conivaptan, Tolvaptan (TOPNOTCH)

27

_____ may occur with rapid correction of hyponatremia

Central pontine myelinolysis (TOPNOTCH)

28

Which is more selective for V2 receptors, Conivaptan or Tolvaptan?

tolvaptan (TOPNOTCH)

29

Thryoid hormone ; For Hypothyroidism, myxedema coma

Levothyroxine (T4), Liothyronine (T3) (TOPNOTCH)

30

T or F: Liothyronine has a faster onset but shorter half-life

TRUE (TOPNOTCH)