Viral and Respiratory Tract Infections Flashcards

1
Q

What are the possible causative organisms of the common cold?

A
Rhinovirus
Coronavirus
Prainfluena virus
Human metapneumovirus
Adenovirus
RSV
Influenza
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2
Q

What are the possible causative organisms of pharyngitis?

A
Adenovirus
Rhinovirus
Parinfluenza virus
RSV
Coronavirus
Human metapneumovirus
Human bocavirus
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3
Q

What are the possible causative organisms of croup?

A

Parainfluenzza virus
Human metapneumovirus
RSV

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4
Q

What are the possible causative organisms of acute bronchitis?

A

RSV
Human metapneumovirus
Influenza
Adenovirus

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5
Q

What are the possible causative organisms of bronchiolitis?

A
RSV
Human metapneumovirus
Parainfluenzza virus
Rhinovirus
Coronavirus
Influenzza
Human bocavirus
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6
Q

What are the possible viral causative organisms of penumonia?

A
Influenza
RSV
Parainfluenza
Human metapneumovirus
Adenovirus
Rhinvirus
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7
Q

What are the symptoms of a common cold?

A

Sore scratchy throat
Rhinorrhoea
Nasal obstruction

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8
Q

For how long does a common cold persist?

A

~1 week

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9
Q

What are the possible complications of a common cold?

A

Otitis media

SInusitis

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10
Q

Severe infections as a result of the common cold occur most often in which groups of people?

A

Elderly
Immunocompromised
Asthma, COPD, CF

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11
Q

Which virus, which is a common cause of the common cold, has the largest RNA virus genome?

A

Coronavirus

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12
Q

What is the most common causative organism of the common cold?

A

Rhinovirus

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13
Q

Pharyngitis is usually the result of viral infection. What symptom points to a viral rather than bacterial cause?

A

The presence of nasal symptoms

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14
Q

Other than respiratory viruses, what can cause pharyngitis?

A

Epstein Barr virus in infectious mononucleosis
HIV seroconversion illness
Herpes simplex virus

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15
Q

Which age group is most commonly affected by croup?

A

Children

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16
Q

What is the distinctive symptom of croup?

A

Distinctive cough

17
Q

What is the incubation period of bronchiolitis?

A

3-5 days

18
Q

Respiratory syncytial virus infection has been linked to the development of which chronic respiratory condition?

A

Asthma

19
Q

What drug is used to treated respiratory syncytial virus infections?

A

Ribvirin (orally, IV, aerosolised)

20
Q

What expensive monoclonal antibody can be given to treat respiratory syncytial virus infections?

A

Palivizumab

21
Q

What are the risk factors for complicated influenza illness?

A
Age <6 months or >65 years
Pregnancy
Morbid obesity
Neurological, hepatic, renal, pulmonary, cardiac and diabetes mellitus patients
Severe immunocompression
22
Q

Neuraminidase inhibitors can be used for prophylaxis is given how many hours before exposure to influenza?

A

48 hours

23
Q

Give examples of neuraminiade inhibitors used to treated influenza?

A

Oseltamivir
Zanamivir
Peramivir
Laninamivir

24
Q

Give examples of M2 inhibitors used to treated influenza

A

Amantadine

Rimantagine

25
Q

Give examples of RNA polymerase inhibitors used to treat influence

A

Favipiravir

Baloxavir

26
Q

Aquatic birds can act as a natural reservoir for what strain of influenza viruses?

A

Influenza A

27
Q

How is influenza diagnosed in the laboratory?

A

Electron microscopy

Tissue culture

28
Q

Respiratory viruses should be collected for laboratory detection via which techniques?

A
Nasal pharyngeal swab
Throat swab
Gargle
Sputum
ETA
BAL
29
Q

What types of vaccine can be used against influenza?

A

Live attenuated quadrivalent vaccine
Quadrivalent inactivated vaccine
Adjuvanted trivalent inactive vaccine