viral infection Flashcards
what do viruses either contain
DNA or RNA
Capsid made up of repeated subunits of a virally encoded protein
cosahedral symmetry:
virus consists of repeated subunits that make up equilateral triangles arranged in a symmetrical fashion
viral replication attachment
interact with specific receptors in target cell
viral replication entry
endocytosis
viral replication uncoating
viral nucleic acid released from capsid
viral replication Nucleic acid and protein synthesis –
host ribosomes used (host polymerases may also be used) to produce new viral proteins
viral replication assembly
nucleic acids and proteins packaged together
then release
viral replication budding
virus released with envelope derived from host cell membrane, doesn’t kill cell
viral replication lysis
viruses accumulates until cell bursts, killing cell
decisive parthogenesis
Cell death due to lysis
Cell death due to immune system
Cell proliferation - cancer
what do cytotoxic T lymphocytes do in immune response
recognise foreign cell surface proteins, signal to infected cell to commit suicide
what other immune response is there
Neutralising antibodies - IgG, IgM
what does it mean if a virus becomes quiescent
no active replication
in viral persistence when may a virus react
after a period of latency
what is a chronic infection
when a virus may remain continually active for years
