Viral STIs Flashcards Preview

Module 6: Repro/Endocrine > Viral STIs > Flashcards

Flashcards in Viral STIs Deck (8)
1

What are the two major forms of HIV and where are they found?

HIV-1 Everwhere
HIV-2 West Africa

2

What is the HIV receptor and co-receptor?

CD4 binds to gp120
CCR5 binds to gp41 - allows fusion of envelopes

3

What are prognostic indicators of faster HIV disease progression?

Higher viral load and lower CD4+ T cell count

4

What are the routes of sexual HIV transmission?

Greater in women and MSM
Vaginal epithelium gets broken
Endocervical cells (ectopy)
Rectal simple columnar epithelium is easy damaged and has lymphocitic infiltrate
Internal prepuse not keratinized

5

When is HIV transmission more likely?

Acute phase and stage 3 - high viral loads
STI coinfection

6

What are symptoms of acute HIV infection?

Flu like symptoms
Lymphadeopathy

7

How do you diagnose HIV?

HIV ab ELISA
p24 ELISA
Western blot of all HIV proteins

8

How do you prevent HIV?

Avoid unprotected sex
Frequent testing
Treating all STIs
Treatment during pregnancy and elective cesarean
Post-natal care (ARV)
Treat high-risk populations with ARVs