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NUTR 302 (Test #3) > Vitamin B1/B2/B3 > Flashcards

Vitamin B1/B2/B3 Flashcards

1
Q

Which two vitamin groups are water-soluble?

A

B-Complex Vitamin’s & Vitamin C

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2
Q

Vitamin B1 is also known as?

A

Thaimin

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3
Q

The structure of vitamin B1 (Thiamin) is known for what two components?

A

Pyrimidine + Thiazole

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4
Q

What is the coenzyme forms of vitamin B1 (Thiamin)?

A

TDP & TPP

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5
Q

What are some prominent sources of vitamin B1 (Thiamin)?

A

Yeast
Pork
Legumes
Whole / Enriched Grains
Sunflower Seeds

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6
Q

How does TDP/TPP (vitamin B1) function as a coenzyme?

A

Catalyzing Decarboxylation of:
Pyruvate & a-ketoglutarate
(KREBS Cycle)

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7
Q

What are the coenzyme reactions of vitamin B1 important for?

A

The release of energy from food in formation of ATP

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8
Q

In an additional function of vitamin B1, TDP is needed for ______ which forms what?

A

Transketolase > forms Pentoses

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9
Q

What are Pentoses used for?

A

Synthesis of Nucleic Acids for RNA/DNA

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10
Q

Vitamin B1 is also essential for _______ Conduction

A

Nerve

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11
Q

Beriberi is a form of ____ Deficiency

A

Vitamin B1

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12
Q

What are symptoms of Beriberi?

A

Dry: Muscle Weakness & Wasting
Wet: Heart Failure with Edema

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13
Q

Wernicke-Korsakoff Syndrome is a form of _____ Deficiency

A

Vitamin B1

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14
Q

Wernicke-Korsakoff Syndrom is associated with?

A

Alcoholism

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15
Q

Wernicke-Korsakoff Syndrom will commonly result in what with relation to Thaimin?

A

Decreased Intake
Decreased Absorption

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16
Q

What population is most at risk for Wernicke-Korsakoff syndrome?

A

Elderly

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17
Q

Large doses of Vitamin B1 supplementation can be helpful with?

A

MSUD (Maple Syrup Urine Disease)

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18
Q

What is an assessment for Vitamin B1?

A

Erythrocyte Transketolase Activity

19
Q

Vitamin B2 is also known as?

A

Riboflavin

20
Q

The structure of vitamin B2 (Riboflavin) is known for what two components?

A

Flavin Molecule + Ribitol

21
Q

What is the coenzyme forms of vitamin B2 (Riboflavin)?

A

FMN & FAD

22
Q

What are some prominent sources of vitamin B2 (Riboflavin)?

A

Milk
Dairy Products
Eggs
Meat
Legumes
Enriched Grains

23
Q

Vitamin B2 (Riboflavin) is sensitive to?

A

UV Light

24
Q

Vitamin B2 (Riboflavin) is essential in the function of what energy system?

A

Electron Transport Chain

25
Q

Vitamin B2 functions in the activation of?

A

B6
Folate

26
Q

Vitamin B2 functions in the reduction of?

A

Glutathione

27
Q

Vitamin B2 acts in the synthesis of?

A

Niacin

28
Q

Vitamin B2 deficiency showcases symptoms of?

A

Cheilosis (cracking of lips)
Angular Stomatitis (cracking corner of mouth)
Glossitis (inflammation of tongue magenta tongue)

29
Q

Vitamin B2 deficiency tends to occur in which populations?

A

Elderly
Some Cancers
Pregnancy
Elevated Metabolisms

30
Q

What is an assessment for Vitamin B2?

A

Red Cell Glutathione Reductase
(FAD is important in reducing glutathione)

31
Q

Vitamin B3 is also known as?

A

Niacin

32
Q

The structure of vitamin B3 (Niacin) is known for what two components?

A

Nicotinic Acid & Nicotinamide

33
Q

What are the coenzyme forms of vitamin B3 (Niacin)?

A

NAD
NADH
NADP
NADPH

34
Q

What are some prominent sources of vitamin B3 (Niacin)?

A

(MFP) Meat, Fish, Poultry
Enriched Grains
Legumes

35
Q

Synthesis of Vitamin B3 (Niacin) occurs from?

A

Tryptophan

36
Q

How many mg of tryptophan equate to 1 mg of niacin synthesized?

A

60 mg for every 1 mg

37
Q

In order for niacin synthesis to occur from tryptophan, what two vitamins and mineral are required?

A

B2, B6, Fe

38
Q

Vitamin B3 (Niacin) functions primarily for?

A

Energy Transformation (FADH or NADH)

39
Q

What are some of the energy pathways were Vitamin B3 operates?

A

Electron Transport Chain
Glycolysis
Pyruvate Dehydrogenase
Krebs Cycle
B-Oxidation

40
Q

Pellagra is associated with Vitamin ___ Deficiency?

A

Vitamin B3

41
Q

Pellagra is also known as the “4D’s” for it’s progressive degeneration? What are the “4D’s”?

A

Dermatitis
Diarrhea
Dementia
Death

42
Q

Medication such as Isoniazid (TB meds) reduces _______ synthesis?

A

Reduced Niacin Synthesis

43
Q

Vitamin B3 Deficiency is associated with?

A

Low Intake (alcoholics)
Elevated Metabolism
Low Tryptophan Diet

44
Q

Vitamin B3 Toxicity showcases symptoms of?

A

Release of Histamine (flushing)
Liver Injury
Competition with Urate for Excretion
Itching
Elevated Glucose

NUTR 302 (Test #3) (7 decks)

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