Vitamin D Flashcards

1
Q

What is the most active form of vitamin D?

A

Calcitriol

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2
Q

Calcitriol is also a ______ ?

A

Hormone

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3
Q

What is the DRI for vitamin D?

A

600 IU/day

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4
Q

What are some food sources of vitamin D?

A

Fish Liver Oils
Fatty Fish
Eggs
Liver
Butter
Fortified Juices
Milk
Shitake Mushrooms

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5
Q

Ergocalciferol is a form of _____ ?

A

Vitamin D2

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6
Q

Cholecalciferol is a form of _____ ?

A

Vitamin D3

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7
Q

Exposure to sunlight converts 7-dehydrocholesterol to _____ ?

A

Vitamin D

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8
Q

Vitamin D is absorbed from _____ with _____ ?

A

Micelle with Lipids

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9
Q

Vitamin D enters circulation via?

A

Chylomicron

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10
Q

In the Liver, cholecalciferol is converted into?

A

25-OH cholecalciferol

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11
Q

In the kidney, 25-OH cholecalciferol is converted via?

A

Parathyroid Hormone (PTH)

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12
Q

Low calcium levels stimulate?

A

Parathyroid Hormone (PTH)

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13
Q

Parathyroid Hormone increases the production of?

A

Calcitriol

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14
Q

Calcitriol stimulates calcium absorption a the ______ ?

A

Intestine

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15
Q

Calbindin stimulates the synthesis of?

A

Calcium Absorption

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16
Q

Low calcium levels stimulate calcitriol through _____ which increases renal calcium ______ ?

A

PTH > Renal Calcium Reabsorption

17
Q

Calcitriol + PTH = ?

A

Osteoclast Signaling

18
Q

Calcitriol may prevent _____ ?

A

Cancer Growth

19
Q

Rickets is the symptoms of?

A

Bowed Legs, Knock-Knees

20
Q

Rickets is the condition of?

A

Not enough calcium in bone & weight-bearing TUT changes in bone structure

21
Q

Blood Calcium is kept normal at the expense of?

A

Bones

22
Q

People with fat malabsorption are at risk of?

A

Vitamin D deficiency

23
Q

Populations at risk of vitamin D deficiency are?

A

Winter Infants (born/remain inside)
Vegans
Elderly
Renal/Liver Disease
Dark Skin

24
Q

Vitamin D Toxicity can result in _______ calcification.

A

Soft-Tissue

25
Q

Nausea & Anorexia are also symptoms of?

A

Vitamin D deficiency

26
Q

What is the upper limit of vitamin D?

A

4000 IU/day

27
Q

What is the best indicator of recent vitamin D intake or sun exposure?

A

Plasma 25-OH cholecalciferol

28
Q

What is the optimal level of Plasma 25-OH cholecalciferol?

A

30-60 ng/mL