Vitiligo & Hyperpigmentation

Question 1

lesion description of vitiligo

Answer 1

-depigmented, macule, patch

Question 2

What is vitiligo?

Answer 2

-chronic (long-lasting), acquired autoimmune disorder that causes macules/ patches of skin to lose pigment or color

Question 3

Tx of vitiligo

Answer 3

-Topical tacrolimus/pimecrolimus (2 yaş üstünde)
-Topical corticosteroids

Larger lesions, more widespread disease, topikal tedaviye yanıt yoksa:
-Narrow band UVB phototherapy/PUVA
-Excimer laser/light therapy (larger lesions, more widespread disease, topikal tedaviye yanıt yoksa)

En son seçenek:
Monobenzyl ether of hydroquinone (widespread cases – complete bleaching)

Question 4

Where is vitiligo located?

Answer 4

Acrofacial alan
ağız kenarı
göz kenarı
distal ekstremiteler
genital alan
axilla
nipple
knee, elbow

Question 5

DDx of Vitiligo

Answer 5

P. Versicolor alba
Idiopathic guttate hypomelanosis
P. Alba
Early stage of scleroderma
Indeterminate leprosy
Syphilis 2nd stage
Tuberous sclerosis
PIH
Nevus anemicus
Nevus depigmentosus and piebaldism; congenital

Question 6

DDx of patches

Answer 6

mycosis fungoides
melesma
cafe-au-lait
mongolian spot
vitiligo
postinflammatory hyperpigmentation