Vol. 3 Flashcards

(153 cards)

1
Q

Osteomalacia labs

A

Inc. ALP, inc. PTH
dec. Phos, dec. serum Ca, dec. urine Ca
Dec. 25-OH-D

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2
Q

Osteomalacia labs

A

Inc. ALP, inc. PTH
dec. Phos, dec. serum Ca, dec. urine Ca
Dec. 25-OH-D

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3
Q

Friedreich Ataxia

A

Spinocerebellar ataxia

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4
Q

Friedreich Ataxia sxs

A

Gait ataxia, dysarthria, frequent falling, cardiomyopathy, resp. complications, skeletal deformities

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5
Q

Friedreich Ataxia genetic

A

aut. rec.

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6
Q

Fetal Hydantoin Syndrome sxs

A

Midfacial hypoplasia, microcephaly, cleft lip and palate, digital hypoplasia, hirsutism, developmental delay.

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7
Q

HCTZ causes what tox

A

gout (urate retention) and hyperCa, HLD

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8
Q

Chagas dz sx

A

Megacolon/megaesophagus, myocarditis, from Latin America

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9
Q

Chagas dz cause

A

Protozoan Trpanosoma cruzi

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10
Q

Histoplasmosis location

A

Histoplasmosis

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11
Q

Histoplasmosis cause

A

Soil, bird, and bat dropplings

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12
Q

Histoplasmosis sxs in immunocompromised

A

Pancytopenia, HSM, LAD

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13
Q

Histoplasmosis labs

A

Inc. LDH, ferritin, liver enzymes

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14
Q

Histoplasmosis dx

A

Urine or serum antigen

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15
Q

Histoplasmosis tx

A

Itraconazole for mild-mod., ampho B for severe

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16
Q

Tx for nephrolithiasis

A
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17
Q

Neuroleptic malignant syndrome tx

A

Dantrolene, bromocriptine, amantadine (DA agonists)

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18
Q

Mycoplasma skin condition

A

Erythema multiforme

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19
Q

Beta-blocker and CCBs toxicity tx

A

Glucagon

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20
Q

Minimal change dz dx

A

Use steroids, diagnostic and therapeutic

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21
Q

Congeital rubella sxs

A

Triad: Cataracts, PDA, Sensorineural hearing loss

Also see IUGR and purpura

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22
Q

Myotonic dystrophy sxs

A

Cataracts, baldness, testicular atrophy/infertility

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23
Q

Toxic megacolon dx

A

SIRS signs and radiographic evidence of colonic distention

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24
Q

Zinc def. sxs

A

Alopecia, dysgeusia, bullous/pustular lesions, impaired wound healing

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25
Selenium def. sxs
Cardiomyopathy
26
When to biopsy for abnormal uterine bleeding
>45 and all postmenopausal | if
27
When to biopsy for abnormal uterine bleeding
>45 and all postmenopausal | if
28
Friedreich Ataxia
Spinocerebellar ataxia
29
Friedreich Ataxia sxs
Gait ataxia, dysarthria, frequent falling, cardiomyopathy, resp. complications, skeletal deformities
30
Friedreich Ataxia genetic
aut. rec.
31
Fetal Hydantoin Syndrome sxs
Midfacial hypoplasia, microcephaly, cleft lip and palate, digital hypoplasia, hirsutism, developmental delay.
32
HCTZ causes what tox
gout (urate retention) and hyperCa, HLD
33
Chagas dz sx
Megacolon/megaesophagus, myocarditis, from Latin America
34
Chagas dz cause
Protozoan Trpanosoma cruzi
35
Histoplasmosis location
Histoplasmosis
36
Histoplasmosis cause
Soil, bird, and bat dropplings
37
Histoplasmosis sxs in immunocompromised
Pancytopenia, HSM, LAD
38
Histoplasmosis labs
Inc. LDH, ferritin, liver enzymes
39
Histoplasmosis dx
Urine or serum antigen
40
Histoplasmosis tx
Itraconazole for mild-mod., ampho B for severe
41
Tx for nephrolithiasis
42
Neuroleptic malignant syndrome tx
Dantrolene, bromocriptine, amantadine (DA agonists)
43
Mycoplasma skin condition
Erythema multiforme
44
Beta-blocker and CCBs toxicity tx
Glucagon
45
Minimal change dz dx
Use steroids, diagnostic and therapeutic
46
Progressive multifocal Leukoencephalopathy
JC virus (junky cerebrum)
47
Myotonic dystrophy sxs
Cataracts, baldness, testicular atrophy/infertility
48
Toxic megacolon dx
SIRS signs and radiographic evidence of colonic distention
49
Zinc def. sxs
Alopecia, dysgeusia, bullous/pustular lesions, impaired wound healing
50
Selenium def. sxs
Cardiomyopathy
51
HIT type 2 cause
Abs against heparin-platelet factor 4 complex
52
When to biopsy for abnormal uterine bleeding
>45 and all postmenopausal | if
53
MEN1 diseases
Pituitary, Parathyroid primary, and Pancreatic
54
MEN2A diseases
Pheo, medullary thyroid cancer, and parathyroid hyperplasia
55
MEN2B diseases
Pheo, MTC, mucosal and intestinal neuromas, marfanoid habitus
56
Paget's labs
Inc. alk phos, nl serum Ca and phos
57
Paget's sxs
Frontal bossing, HAs, CN palsies
58
Cryoglobulinemia sxs
Palpable purpura, glomerulonephritis, systemic sxs, arthralgias, hepatosplenomegaly, peripheral neuropathy, and hypocomplementemia
59
PSC labs
Enzymes
60
PBC abs
Anti-mitochondrial
61
PBC pathology
Intrahepatic bile ducts
62
PBC tx
ursodeoxycholic acid
63
Acute/Chronic hepatitis Abs
Anti-smooth muscle and LKM
64
Churg-Strauss syndrome and microscopic polyangiitis abs
P-ANCA
65
Herpangina sxs
Gray vesicles and ulcers on posterior oropharynx
66
Herpangina cause
Coxsackie A virus
67
Acute pancreatitis and WBCs
Leukocytosis
68
Fibromyalgia tx
Tricyclic antidepressants
69
Oxybutynin use
Urge incontinence, not stress
70
Tx for Stress incontinence
Kegel's and urethropexy
71
Primary CNS lymphoma appearance
Solitary, Weakly enhancing, and periventricular ring-enhancing lesion. EBV DNA in CSF
72
Progressive multifocal Leukoencephalopathy
JC virus (junky cerebrum)
73
Increases risk for INtraventricular hemorrhage
Low birth weight and prematurity
74
Pseudotumor cerebri palsy
CN VI palsy
75
Pseudotumor cerebri drug causes
tetracyclines and vit A. excess
76
Osteosarcoma appearance
Mix of radiodense and radiolucent areas
77
SLE complement
low C3 and C4
78
SLE arthritis
non-deforming
79
Breech position correction
If present >37 weeks
80
Bernard-Soulier sxs
Aut. rec., Absent plt glycoprotein Ib-IV-V, mild thrombocytopenia, GIANT platelets
81
Ziprasidone toxicity
QT prolongation
82
Uncong. hyperbili genetic
Gilbert and Crigler-Najjar
83
Dubin-Johnson
Black liver, benign
84
Rotor
Nl looking liver, benign
85
Cause of erysipelas
Group A beta-hemolytic strep
86
Autoimmune hemolytic anemia causes
Warm vs. Cold agglutinin
87
Warm agglutinin causes
Drugs, infections, SLE, immunodeficiency, CLL
88
Warm agglutinin labs
Direct coombs + with anti-IgG, anti-C3, or both
89
Warm agglutinin tx
steroids, splenectomy
90
Cold Agglutinin causes
Mycoplasma, EBC, lymphoproliferative
91
Cold Agglutinin sxs
livedo reticularis and acral cyanosis with cold exposure
92
Cold Agglutinin labs
Direct Coombs + with anti-C3 or anti-IgM, not usually IgG
93
Cold Agglutinin tx
Rituximab +/- fludarabine
94
Fibromyalgia tx
Tricyclic antidepressants
95
lead poisoning cells
microcytic, basophliic stippling
96
Vasa previa sxs
Painless bleeding, only fetal blood
97
Placenta previa sxs
Painless bleeding, not as bad bleeding as vasa previa
98
PTU and methimazole tox
may cause agranulocytosis, discontinue if fever present
99
Thyrotoxicosis tx
propranolol
100
Renal DI drug cause
Demeclocycline to cause renal ADH resistance
101
Osteoid osteoma sxs
Proximal femur, pain worse at night, highly responsive to NSAIDs for pain, small round lucency, regresses spontaneously
102
Osteosarcoma appearance
Mix of radiodense and radiolucent areas
103
Pathognomomic sign of Zollinger-Ellison
Jejunal ulcer
104
Etomidate and adrenal
Can trigger acute adrenal crisis
105
DIGFAST
Distractibility, Impulsivity, Grandiosity, Flight of Ideas, Activity, Sleep, Talkativeness
106
Akathisia tx
Benzo
107
Lidocaine use in ACS
Inc. risk of asystole
108
NPH triad
wet, wobbly, wacky
109
AFP increased in...
NTDs, ventral wall defects, multiple gestation
110
Ivermectin use
Strongyloides and onchocercosis
111
Croup tx
Racemic epinephrine before anything else invasive
112
Vaginismus cause
Psychological
113
Caput succedaneum location
diffuse, ecchymotic, crosses suture lines, portion of head presenting during vertex
114
Pyloric stenosis RFs
first-born boys age 3-5 wks
115
pyloric stenosis tx
pyloromyotomy
116
AL amyloidosis causes
Light chains, Mult. myeloma, Waldenstroms macroglobulinemia, lambda chains
117
AA amyloidosis causes
Inflammatory: RA, IBD, chronic inflamm., chronic infxns (osteo, TB), Beta-2 microglobulin, apolipoprotein, transthyretin
118
AA amyloid stain
apple-green birefrience on congo red staining
119
Nephrotic syndromes
Membranous, FSGS, MCD, amyloidosis
120
Lysosomal Storage Diseases
!!!!!!!!!
121
Light's criteria
For exudates: Pleural fluid protein/serum protein >0.5 Pleural LDH/Serum LDH >0.6 Pleural LDH >2/3 upper limit nl for serum LDH
122
SJS causes
sulfa drugs, anticonvulsants, mycoplasma, vaccines
123
Acquired torticollis causes
URI, minor trauma, cervical lymphadenitis, also retropharyngeal abscess, atlantoaxial subluxation
124
Polymyositis
Slowly progressive prox. weakness of lower extremity
125
Asplenia tx
Give PCV13 first than PPSV23 8 wks later
126
How to distinguish primary from secondary adrenal insuff.
Look at mineralocorticoid function, still present in central (secondary) insuff.
127
Pyrophosphate crystals
Rhomboid shaped, + birefringent
128
Dacrocystitis
Lacrimal sac infection
129
Dacrocysitis cause
S. aureus, beta-hemolytic strep
130
Negatively birefringence looks like
Yellow is north-south (like the continents) blue is east-west (like the oceans on the sides)
131
Endometriosis
Pain peaks before menses
132
VACTERL
vertebral anomalies, anal atresia, cardiac defects, TE fistula or esophageal atresia, renal and radial anomalies and limb defects
133
CMV retinitis sxs
Yellowish-white patches of retinal opacification and retinal hemorrhages
134
CMV retinitis tx
Ganciclovir or foscarnet
135
Nl A-a gradient
136
Disseminated gonoccocal infection
Triad of tenosynovitis-dermatitis-migratory polyarthrlagias. Or can be purulent arthritis
137
Croup tx
Racemic epinephrine
138
Parkinsonism cause
Overactive cholinergic and underactive DA neurons
139
anorexia cutoff
BMI
140
Anorexia tx
CBT or olanzapine if no response
141
Bulimia tx
CBT or SSRI
142
Refeeding syndrome
Fluid and electrolyte shifts lead to arrhythmias and HF
143
ALL stainin
+ TdT, PAS
144
Myeloblasts contain what
Peroxidase positive material
145
Rotavirus vaccine tox
Inc. intussusception
146
Lymphadenitis cause
S. aureus
147
Rabbits bacteria
Franciscella tularensis
148
Peptostreptococcus source
hx of periodontal dz
149
Ascites tx
Na+ and H20 retention, then spironolactone, then loop, then paracentesis
150
Phenytoin tox
horizontal nystagmus
151
Zenker's pathophys
Posterior thru cricopharyneal
152
Leading cause of mitral valve prolapse in developed countries
Myxomatous degeneration
153
Number needed to treat
Inverse of Absolute Risk Reduction (1/ARR)