Vol. 5 Flashcards

(70 cards)

1
Q

Clozapine seizure effect

A

lowers threshold

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2
Q

G6PD triggers

A

infections and drugs (sulfa, antimalarials, nitrofurantoin)

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3
Q

Most common metastatic brain cancers

A

lung > breast > unknown primary > melanoma > colon

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4
Q

tx severe hyperCa

A

> 14 mg/dL, NS and calcitonin. Avoid loops unless volume overloaded

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5
Q

erysipelas cause

A

GABHS (strep pyo), raised borders

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6
Q

cocaine and fetal effects

A

jejunal atresia (triple bubble: stomach, duodenum, jejunum)

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7
Q

Theophylline tox

A

CNS stim. and cardiac tox

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8
Q

PPV

A

Of all patients with positive test, what fraction is a true positive

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9
Q

best test for recurrent MI

A

CK-MB

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10
Q

how often nonstress test

A

weekly in 3rd trimester

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11
Q

pneumocystis tx

A

bactrim is first line + steroids if severe disease

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12
Q

second line tx for pneumocystis

A

pentamidine, atovaquone, bactrim and dapsone, clinda and primaquine

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13
Q

Fanconi’s anemia

A

Pancytopenia and congenital abnormalities

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14
Q

Diamond-Blackfan anemia

A

Congenital Pure red cell aplasia

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15
Q

endometritis tx

A

IV clinda and IV aminoglycoside

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16
Q

causes of variable decels

A

Cord compression, oligohydramnios, cord prolapse

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17
Q

are variable decels always bad

A

if no relation to contractions, they are common and fine

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18
Q

neuroblastoma origin

A

neural crest derived

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19
Q

neuroblastoma dx

A

serum and urine catecholamines (HVA and VMA) elevations, but no pheo sxs

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20
Q

Wilm’s tumor source

A

Metanephros, renal parenchyma

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21
Q

Herpangina cause

A

Coxsackie A (B is myocarditis)

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22
Q

dihydropyridine CCBs

A

nifedipine and amlodipine

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23
Q

non-dihydropyridine CCBs

A

diltiazem and verapamil

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24
Q

which CCB class causes angioedema

A

I think the dihydropyridine group???

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25
Pinealoma
commonly GCT, can produce hCG, can cause obstructive hydrocephalus
26
HSP kidney histo
IgA deposition in mesangium
27
HSP sxs
palpable purpura, abdominal pain, arthralgias, kidney failure
28
How does congenital hypothyroidism look
Normal birth, then develops large tongue, abd. bloating, umbilical hernia, weakness, hypotonia, jaundice
29
Primary amenorrhea definition
No menarche by Age 15
30
dx for Turners
Karyotype, then FISH
31
breastfeeding failure jaundice
not enough fluids b/c of not enough breastfeeding means they reabsorb more bile acids . Happens in first week of life
32
breast milk jaundice
nl breastfeeding, not dehydrated, but high levels of beta-glucuronidase in breast milk lead to more reasbroption. Starts age 3-5 days, peaks at 2 weeks
33
sodium loss in HHNK
free water loss is great than sodium loss
34
hemochromatosis infection risk
increased risk to yersinia, vibrio vulnificus, yersinia enterocolitica
35
Staph aureus PNA
nodular infiltrate with cavitation
36
can you have MDD episodes in dysthymia?
yes, it just wont be pure dysthymia
37
janeway lesions
palms and soles, non-painful, macular
38
osler nodes
painful, violaceous nodules on fingertips and toes
39
roth spots
edematous and hemorrhagic lesions of the retina (IE)
40
reye syndrome histo
microvesicular fatty infiltration and hepatic mitochondrial dysfunction
41
reye syndrome associations
influenza B, then A, and varicella zoster
42
Macrovesicular fatty chances
alcoholic and NAFLD
43
what elevated in folate deficiency
homocysteine
44
what elevated in B12 deficiency
homocysteine and methylmalonic acid
45
painless hematochezia in a young toddler
Meckel's diverticulum
46
antiphospholipid syndrome tx in pregnancy
aspirin and LMWH
47
indications for parapneumonic tube thoracostomy
pH
48
tx variant angina
CCBs and nitrates
49
cat bite tx
amox-clav for pasturella multocida
50
echinococcus animals
sheep and dogs
51
klumpke paralysis hand
CLAW
52
Wernicke encephalopathy sxs
encephalopathy, ocular dysfunction, and gait ataxia
53
Marfan's lens subluxation
Upwards
54
MGUS follow up test
metastatic skeletal bone survery
55
aspirin exacerbated respiratory disease
seen with asthma, chronic rhinosinusitis with nasal polyposis
56
Tx for baby born to mom with HBV
HBIG and HBV vaccine
57
tx for antiphospholipid syndrome in pregnancy
low-dose aspirin
58
thyroid labs
TSH and T4
59
Tay-Sachs cells apperance
onion-skin lysosomes
60
Patau apperance
cleft lip/Palate, holoProsencephaly, Polydactyly, | rocker-bottom feet, MR; death by 1 y/o
61
Patau mnemonic
Puberty is 13
62
Edwards mnemonic
Election age is 18
63
Williams syndrome apperance
Elfin facies, Extreme friendliness w/ strangers, | well-developed English, MR
64
Williams mutation
7q-
65
Cri-du-chat mutation
5p-
66
Cri-du-chat appearance
microcephaly, cardiac problems, high-pitched | meowing, epicanthal folds, MR
67
Eisenmenger syndrome
Pulmonary HTN reversing direction of shunt
68
ASD presentation
low-grade systolic murmur, fixed S2, and frequent colds
69
When to get prenatal imaging
Level-I U/S at 18-22 wks is standard of care
70
Wilson disease dx
Low serum ceruloplasmin, increased urinary copper, kaiser-fleischer rings