Week 1/Chpt1 Flashcards

(75 cards)

1
Q

What is pharmacology

A

The study of drugs and their interactions with living cells and systems

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2
Q

What are the uses of drugs

A

Diagnosis
Treatment of disease
Prevention of disease

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3
Q

What do “drugs” include (4)

A

Synthetically derived compounds
Vitamins
Minerals
Herbal supplements

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4
Q

Role of dental hygienist in relation to pharmacology

A

Knowledge of pt meds/ health hx
Understanding of actions indications adverse reactions and therapeutic use

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5
Q

Who is usually the 1st to assess the patients medication history

A

Dental hygienist (DH)

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6
Q

In an emergency situation such as anaphylactic shock, what is administered quickly

A

Epinephrine

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7
Q

Early morning appointments should be scheduled for what pts

A

Asthmatic and anxious patients to reduce anxiety

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8
Q

Diabetic patients should be scheduled for an appointment when?

A

90 mins after meals and meds

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9
Q

Premedication/prophylaxis should be done how long prior to invasive dental treatment

A

30-60mins

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10
Q

All drugs have at least how many names

A

2

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11
Q

Each drug has only 1 ____ name, but can have several _____ names

A

Generic; trade

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12
Q

Chemical name/code name is given by

A

Company investigating the drug, drugs chemical structure

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13
Q

Trade name/brand name is given by?

A

Pharmaceutical company that discovers the drug

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14
Q

Generic name: “official name” refers to? Example?

A

Only 1 name per drug, before marketed not capitalized
Example: ibuprofen

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15
Q

After the original patent have expired, other companies can market the _____ name under a trade name of their choice. Example?

A

Generic name
Example: Advil

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16
Q

Generic substitution provides what kind of results at a reduced cost

A

Equivalent therapeutic results

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17
Q

What does chemically equivalent mean

A

2 formulations of a drug meet the chemical and physical standards

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18
Q

What does biologically equivalent mean

A

2 formulations of a drug produce similar concentrations of the drug in the blood and tissues

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19
Q

What does therapeutically equivalent mean?

A

2 formulations of a drug have equal therapeutic effects in a clinical trial

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20
Q

A drug consumed can be ____ equivalent but NOT _____ or _______ equivalent

A

Chemically; biologically; therapeutically

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21
Q

If it is biologically equivalent then it is

A

Therapeutically equivalent

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22
Q

Before drug products are authorized for sale in Canada, who reviews them to assess their safety, efficacy and quality

A

Health Canada

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23
Q

Drug products include?

A

Prescription and non prescription pharmaceuticals, disinfectants and sanitizers with disinfectant claims

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24
Q

Prior to being given market authorization a manufacturer must present

A

Substantive scientific evidence of a products safety, efficacy and quality as required by the food and drugs act regulation

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25
When a product is offered for sale in Canada to treat or prevent disease or symptoms it is regulated as a drug under?
The food and drugs act
26
What 2 acts regulate narcotics in Canada
-Canadian food and drugs act (FDA) -Controlled substances & drugs act (CDSA)
27
FDA requires that drugs comply with
Prescribed standards
28
FDA prohibits sale of drugs that are
Contaminated or unsafe
29
CDSA governs the
Possession, sale, manufacture production and distribution of narcotics
30
CDSA requires that only
Authorized persons possess narcotic substances
31
Authorized persons who can possess narcotic substances includes
Licensed manufacturers/distributors, pharmacists, practitioners, persons in charge of hospitals, or a person who has secured narcotics after filling a legal prescription
32
Clinical evaluation of a new drug takes how long from when the drug is synthesized to pharmacy shelves
12 years
33
Preclinical testing of a new drug involves what? How long does it last?
Animal studies; measures acute/chronic toxicity, median lethal dose Lasts about 3 years
34
Clinical studies of a new drug occurs in how many phases? (Human)
4
35
Phase 1 of clinical studies of a new drug involves what
Small and then increasing doses given to limited healthy human volunteers; to determine safety
36
Phase 2 of clinical studies of a new drug involves what?
Larger group of humans given the drug. To determine effectiveness
37
In phase 2 of new drug clinical studies, if any adverse reactions occur they are reported to?
FDA
38
What does phase 3 of clinical studies of a new drug consist of?
Group of patients given drug with the condition the drug is for
39
Phase 3 determines what?
Safety Efficacy and Dosage of the drug
40
Phase 4 of clinical studies of a new drug consists of what
Post marketing surveillance -toxicity of drug reported after released -removed off shelves if toxic
41
The CDSA is extremely important because it sets current requirement for
Writing prescriptions
42
Federal law divides controlled drugs into how many schedules according to abuse potential
5
43
Describe schedule I drugs
Highest abuse potential -no accepted medical use; experimental use only/research
44
What is an example of a schedule I drug
Heroin LSD Hallucinogenics
45
Schedule II drugs require
A written prescription with providers signature. NO REFILLS -high abuse potential
46
Examples of schedule II drugs
Oxycodone Morphine Amphetamine
47
Schedule III drugs have moderate abuse potential; no more than how many prescriptions in 6 months?
5
48
Example of schedule III drugs
Codeine mixtures (Tylenol 3)
49
Schedule IV drugs have a lesser abuse potential. No more than how many prescriptions in 6 months?
5
50
Example of schedule IV drug
Diazepam (Valium) Tramadol (ultram)
51
Describe schedule V drugs
Least abuse potential -can be bought otc
52
Schedule II and IV require what?
Prescription
53
What is a schedule I drug dental hygienists are allowed to prescribe
0.12% chlorohexidine gluconate
54
Package inserts are literature about the drug between manufacturer and FDA. What kind of information does this contain?
FDA approved for use Contraindications Warnings Adverse reactions Drug interactions Dose and administration
55
FDA requires manufacture to display black box warning in package insert. What is the purpose of this?
Draws attention to warnings for both prescriber and patient -for serious safety concerns
56
What are orphan drugs
Developed to treat rare medical conditions
57
When are drugs recalled?
If there is reasonable probability that their use will have serious adverse health effects and or death
58
What is the primary measuring system in pharmacy
The metric system (mg, mL, L)
59
Prescription format has 3 parts which include
Heading Body Closing
60
What does the heading on a prescription include
-Name address phone of prescriber (printed) -name address age phone of pt (written) -date of prescription (not legal if no date)
61
Body of a prescription includes
Name and dose size/concentration of drug Amount to be dispensed Directions to pt
62
Closing of the prescription includes?
Prescribers signature DEA # (if required) Refill instructions
63
Abbreviation: ‘q’ means
Every
64
Abbreviation: ‘d’ means
Day
65
qod means
Every other day
66
hs means
At bedtime
67
ac means
Before meals
68
pc means
After meals
69
prn means
As needed
70
bid
Twice per day
71
tid
Three times a day
72
qid
Four times a day
73
ud
As directed
74
PO
By mouth
75
Law requires all prescriptions be labeled with what
Name of medication and strength