Week 10 Protein Metabolism Flashcards

1
Q

What is the function of protein?

A

Structural proteins
Transport
Enzyme function
Hormones

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2
Q

What is the structure of amino acids?

A

An amino group-two hydrogen atoms and a nitrogen atom
A carboxyl group (COOH)
In the middle there is an organic chain that consists of (C, O, H, N, S)

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3
Q

What are the proteins held together by?

A

Peptide bonds

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4
Q

What type of reaction form a peptide bond?

A

A condensation reaction

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5
Q

What causes the primary protein structure?

A

Amino acid sequence

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6
Q

What causes the secondary protein structure?

A

Hydrogen bonds between amino acids within the peptide chain

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7
Q

What causes the tertiary protein structure?

A

Attractions between alpha-helices and beta sheets

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8
Q

What causes quaternary protein structure?

A

Two or more peptide chains form a create the building blocks of a functional enzyme

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9
Q

What happens if the protein is denatured?

A

Loss of structure and biological activity

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10
Q

Is protein stored as an energy substrate?

A

No

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11
Q

What is the turn over rate of protein?

A

Fast turnover rate

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12
Q

What is protein a rapid response to?

A

Starvation

Training

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13
Q

How is protein metabolism regulated?

A

By hormones

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14
Q

What are the enzymes that regulate protein turnover?

A

Proteinases

Peptidases

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15
Q

Why is protein as an energy source minimal in exercise?

A

Nitrogen excretion requires ATP expenditure

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16
Q

Can all amino acids be degraded?

A

Yes

17
Q

What does amino acid degradation require? What is it known as?

A

Removal of nitrogen from the amino acid molecule (deamination)

18
Q

What can the protein enter TCA cycle as?

A

Pyruvate
Acetoacyl-coA
Acetyl-coA

19
Q

When nitrogen is released from amino acids what is released?

A

Ammonia (NH3+)

20
Q

What is used to transport ammonia?

A

Alanine and glutamine

21
Q

What is occurring in the body if you have a negative nitrogen balance?

A

Muscle wastage

22
Q

What do proteins consist of?

A

Amino acids

23
Q

What is deamination?

A

A process where the amino group (NH2) is removed from a protein molecul

24
Q

After deamination what happens to the amino group and the carbon skeleton?

A

Amino group is converted into urea (using ATP)

Carbon skeleton can then enter the TCA cycle