Week 11 (Digestive System) Flashcards
(14 cards)
DIGESTIVE SYSTEM
The digestive system performs the following functions:
Mechanical and chemical processes of digestion
Absorption of nutrients
Elimination of wastes
Divisions of the Digestive System
Alimentary canal / gastrointestinal (GI) tract
Accessory digestive organs
The digestive system consists of a hollow, muscular tube that extends from the oral cavity to the anus.
FUNCTIONS OF THE DIGESTIVE SYSTEM
Ingestion:
The process of taking in food.
Motility:
Controlled movement of materials through the digestive tract
Propulsive movement: Unidirectional
Mixing movement: Bidirectional
Digestion:
Mechanical Digestion: Physical breakdown of food (chewing, churning, segmentation)
Chemical Digestion: Enzymes break down macromolecules into usable nutrients
Carbohydrates → Monosaccharides
Proteins → Amino acids
Lipids → Fatty acids and glycerol
Nucleic acids → Nucleotides
Secretion:
Digestive juices from glands
Hormones from endocrine glands
Regulates digestion, secretion, absorption, GI motility
Absorption:
Digested food into bloodstream
Fluids and electrolytes
Maintains fluid and electrolyte balance
Elimination of Wastes:
Removal of indigestible substances
Defecation
Immune Function:
Lymphatic tissue along GI tract aids immune defense
Oral Cavity (Mouth)
Functions: Ingestion
Mechanical Digestion: Teeth chew, tongue mixes food
Chemical Digestion: Salivary amylase starts carb digestion
Pharynx (Throat)
Passageway for food, liquids, air
Moves food into esophagus
Epiglottis covers trachea when swallowing
Esophagus
Propels food to stomach via peristalsis
UES and LES regulate movement
Deglutition = Swallowing
Stomach
Functions: Temporary food storage (1.5L), mixing movements
Mechanical Digestion: Churning
Chemical Digestion: Protein digestion starts
Secretion: Gastric juice, gastrin
Regulates chyme to small intestine
Gastric Juice Composition:
HCl: pH 2, kills bacteria, activates pepsin
Pepsinogen → Pepsin
Intrinsic Factor: B12 absorption
Mucous: Protects lining
Small Intestine
~20 ft long: Duodenum, Jejunum, Ileum
Duodenum: Secretes juices, chemical digestion
Jejunum: Absorbs 90% of nutrients
Ileum: Absorbs water, bile salts, B12, remaining nutrients
Motility: Segmentation, peristalsis
Secretion: Intestinal juice with enzymes
Main site of digestion/absorption
Villi and microvilli → increased surface area
Large Intestine
Divisions: Caecum, Colon (ascending, transverse, descending, sigmoid), Rectum
Functions:
Motility: Mixing, peristalsis
Absorption: Water, electrolytes
Storage: Feces
Elimination: Defecation
Vitamin synthesis by bacteria (e.g., B12, K)
Teeth
Mastication: Breaks down food
Increases surface area for enzymes
Salivary Glands
Three pairs: Parotid, Sublingual, Submandibular
Saliva:
Contains amylase (carb digestion)
Moistens food
Protects enamel, inhibits bacteria
Stimulates taste buds
Liver
Functions:
Secretes bile (bile salts, bicarbonate, lecithin)
Bile emulsifies lipids
Metabolizes/detoxifies drugs/hormones
Stores vitamins/minerals (A, D, E, K, B12)
Activates vitamin D
Synthesizes plasma proteins
Gallbladder
Stores & concentrates bile (up to 20x)
Releases bile for fat digestion
Pancreas
Endocrine: Insulin, glucagon, somatostatin → blood
Exocrine: Pancreatic juice (enzymes + bicarbonate) → duodenum
-Enzymes digest carbs, proteins, fats
-Bicarbonate neutralizes stomach acid