Week 11: Fat Soluble Vitamins Flashcards

(29 cards)

1
Q

What is vitamins a’s, precursor

A

Also known as retinol, retinal, retinoic acid.
- Beta(β)-Carotene is the precursor (also termed provitamin)
- Not all β-Carotene converted to Vitamin A
- Absorption of β -Carotene less efficient than that of Vitamin
A
- 6µg β-Carotene equivalent to 1µg Vitamin

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2
Q

Describe vit a 3 roles

A
  • Vision:
    -> helps maintain a crystal clear cornea.
    -> Participates in conversion of light energy into nerve impulses in the retina
  • healthy epithelial cells:
    -> Vit A participates in protein
    synthesis and cell differentiation- Epithelial tissue
    -> Skin – Vit A helps protect it against damage from sunlight.
    -> Mucous membrane integrity - It helps differentiate epithelial cells and goblet cells
  • Growth
    -> Men: Retinol participates in sperm
    development.
    *-> Women: Vitamin A supports normal fetal
    development during pregnancy.
    -> Children lacking vitamin A fail to grow
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3
Q

What is vit a rdi for men and female

A

RDI men: 900 μg RE/day; women: 700 μg RE/day

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4
Q

What is the vit a UL

A

3000 μg RE/day.

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5
Q

What is the deficiendy disease due to vit a

A

Hypovitaminosis A
– Impaired immunity and susceptibility to infectious diseases.
– Night blindness.
– Blindness (Xerophthalmia).
– Keratinisation – changes in epithelial cells results in
keratinisation, rough, dry and scaly skin.

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6
Q

What is the toxicity disease due to vit a

A

Hypervitaminosis A.
– Chronic toxicity symptoms = liver
abnormalities, weakened bones
contributing to osteoporosis, cause
birth defects
– Acute toxicity symptoms = blurred
vision, nausea, vomiting, vertigo,
headaches and pressure in the skull.
– Vitamin A toxicity – can occur with
concentrated amounts of the
preformed vitamin A

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7
Q

What are 3 common food sources of vit a

A

beef live,r sweet potato, carrots

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8
Q

Can vit d be prof by body

A
  • Body can synthesis it, with help from the sun, from
  • a precursor that the body makes from cholesterol.
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9
Q

What is the vit d Ai and UL

A
  • AI 5 μg/day for adults 19–50 years old.
  • UL: 80μg/day
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10
Q

What is vit d’s main role and 3 ways how

A
  • maintain blood levels of Ca and P
    –> enhancing GIT absorption
    –> enhances reabsorption from kidneys
    –> enhances mobilisation from bones into the blood
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11
Q

What are 3 factors that contirbute to vit d deficiency

A
  • Dark skin
    – Breastfeeding infants by Vit D deficient mothers
    – Lack of sunlight
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12
Q

What are 3 vit d deficiency disorders

A
  • Rickets in children.
  • Osteomalacia and Osteoporosis in adults.
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13
Q

3 reasons why elderrs are at a higher risk of vit d deficiency

A
  • Skin, liver and kidneys lose capacity to make & activate Vit D
  • Older people typically drink little or no milk
  • Spend more time indoors and often wear protective clothing
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14
Q

Who are 4 other groups of people who are at risk of vit d deficiencty

A
  • Dark skinned people of either sex, particularly migrants & those wearing modest dress
  • People with a disability or chronic disease
  • Fair skinned people and those at risk of skin cancer who avoid sun exposure
  • People working in a closed environment
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15
Q

What are 3 health benefits of vit d

A

Diabetes.
– Cardiovascular disease., obesity

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16
Q

What leads to vit d toxicity and what disease?

A
  • Hypervitaminosis D
    – Vitamin D from sunlight and food is not likely to cause toxicity
    – High-dose supplements may cause toxicity.
17
Q

What are 3 common symptoms of vit d toxicity

A
  • Elevated blood calcium
    – Calcification of soft tissues (blood vessels, kidneys, heart, lungs and tissues around joints).
    – Frequent urination.
18
Q

What are 3 sources of vit d

A
  • can be sysntehsised in body with sun
  • Fortified milk, butter and margarine.
    – Egg yolks and liver.
    – Fatty fish (erg. Salmon, herring, mackeral) and their oils.
  • Without adequate sunshine, fortification or supplements, vegans may not meet Vit D needs.
19
Q

What is the main role of vit e

A

A fat soluble antioxidant, main action is to stop the chain of free radicals/producing more free radicals

20
Q

What is the AI for men and women and the UL

A
  • men: 10 mg /d; women: 7 mg/d.
  • Upper Level: 300 mg/day
21
Q

Describe how to minimise vit e losses

A

Sensitive to heat and oxygen, therefore fresh- food sources preferable.

22
Q

What are vit e deficiency disease adn 2 symptoms of defiency

A
  • defifiency rare.
  • Erythrocyte haemolysis (Haemolyticanaemia):
    –> Occurs in premature infants. – Can be treated with vitamin E.

– Loss of muscle coordination and reflexes.
– Impaired vision and speech, nerve damage.

23
Q

Is there toxicity symptoms of vit e

A
  • Rare and the least toxic of the fat-soluble vitamins.
24
Q

What are 3 common food sources of vit e

A
  • Polyunsaturated plant oils such as margarine, salad dressings and shortenings.
    – Leafy green vegetables.
    – Wheat germ+ Wholegrain foods.
25
What is the role of vit k
Synthesis of blood clotting and bone proteins -> metabolism o fbone protein (osteocalcin) -> Without Vit K, osteocalcin cannot bind to minerals that form bones = low bone density.
26
What is the vit k AI for men and women
men:70μg/d; women:60μg/d
27
What are the 3 food sources of vit k
- can be synthesised in body by gi bacteria - Liver - Leafy green vegetables (e.g. Spinach, lettuce, brussels sprouts and cabbage - Milk
28
What are the deficency disease of vit k and symptom
(Haemorrhagic Disease): – Primary deficiencies rare - Deficiency can cause haemorrhaging
29
Is there any toxicity symtpoms of vit k
Rare