Week 2 Flashcards
What is Epidemiology?
Epidemiology is the study of the distribution and determinants of health-related states or events (including disease), and the application of this study to the control of diseases and other health problems
What is the goal of epidemiology?
determine whether there is an ASSOCIATION between an exposure and a disease or adverse health outcome”
AND`
“If so, determine whether the observed association reflects a CAUSAL RELATIONSHIP of the exposure to the disease outcome
What are the 3 main study types?
Randomised trials
Cohort study
Case control study
What is the formula for Relative risk?
Ratio of risk of disease in exposed people / risk of disease in the non-exposed
What so the values of RR mean
1/1 = no association 2/1 = positive association 1/2 = negative association (could be protective)
How muhc attributal risk os needed to deem something causal?
> 50%
What do you need to consider to move association to causal?
- was it there before or after?
- is it dose dependent
- it has to be biologically plausilbe
What is a communicable disease?
Can transmitted from one person to another and is caused by an infectious agent that is transmitted from a source or reservoir to a susceptible host
What are the main types of outbreak?
General outbreak
Point source outbreak
Propagated outbreak
what is a generla outbreak?
General outbreak - Occurrence of new cases of a disease clearly in excessof the baseline frequency of the disease in a defined community over a given time period
what is a point source outbreak?
– An outbreak due to exposure of a group of people to a noxious influence that is common to the individuals in the group
– The exposure is briefand essentially simultaneous, resultant cases all develop within 1 incubation period of the disease
What is a propagated outbreak?
– An outbreak where there are multiple exposures over a period of time, from host to host (directly or indirectly), resulting in cases that are not within1 incubation period
What are the different types of immunity?
active
passive
inherent
herd
What is the epidemiological triad of disease?
Host
Agent
Environment
(vector in middle)
What is the process of disease transmission
Agent Reservoir Portal of exit Mode of transmission Portal of entry Susceptible host
What are the DIRECT modes of disease transmission
Agent Reservoir Portal of exit Mode of transmission Portal of entry Susceptible host
What are the INDIRECT modes of disease transmission
– Air-borne –Vehicle-borne –Vector-borne –Fomite-borne –Hand-borne
What is an emergiing infectious disease?
Emerging infectious diseases are diseases that have appeared for the first time or that have occurred before appeared in populations where they have not previously been reported
What is a re-emerging infectious disease
Re-emerging infectious diseases are familiar diseases caused by well-understood organisms that were once under control or declining but now are resistant to common drugs or gaining new footholds in the population and increasing in incidence.
What are the pricniples for control of communicable disease?
Rapid Assessment Prevention Surveillance Outbreak Control Disease Management
What conditions increase the spread of infectious diseases?
Global travel
Globalisationof food supply and centralisationof food processing
Population growth, increased urbanisationand overcrowding
Migration due to wars, famines, and natural disasters
Irrigation, deforestation, and reforestation projects that alter habitats
Human behaviors, such as IV drug use and risky sexual behavior
Increased use of antimicrobial agents and pesticides
Increased human contact with wilderness habitats
What measures can be used to prevent communicable disease?
–Good site planning –Provision of basic clinical services –Provision of appropriate shelter –Clean water supply –Sanitation –Mass vaccination against specific diseases –Regular and sufficient food supply –Control of vectors
What is primary prevention?
Increasing the resistance of the host Inactivating the agent Interrupt the chain of infection Restricting spread of infection: –Isolation –Quarantine –Segregation –Personal surveillance
What is secondary prevention?
Activities targeted at detecting disease at earliest possible time to:
–Begin treatment
–Stop progression
–Protect others in the community
Examples of activities:
–Case finding
–Health screening
–Health education