WEEK 2 ONC NURSING

Question 1

Why do we work with a MDC approach

Answer 1

best practice
contunity if care
pathway or protocol
referal
audit

Question 2

benefits of the MDC approach

Answer 2

incidental info
treatment planning

communication
survival
clinical trial
emotional needs
duplication

Question 3

list some available cancer treatment options

Answer 3

surgery
radiation
chemo
targeted therapy
immunotherapy
hormone therapy
transplant

Question 4

what is non adjuvent therapy

Answer 4

all treatment administered before primary cancer treatment

Question 5

what is adjuvent therapy

Answer 5

therapy administered after primary treatment

Question 6

how does chemotherapy work

Answer 6

• targets rapidly dividing cells
• intereres with DNA replication by damaging DNA that apoptosis occurs
• can’t distinguish between healthy and bad so kills all

Question 7

distinguish between cell cycle specific chemo and non specific cell cycle

Answer 7

cell cycle specific
* acts on cells in specific cell phase
* more effective in rapid growing cancers

non specific
* acts on cells no matter what the phase
* effects cells in resting phase
* more effective in slow growing cancers

Question 8

describe the cell kill hypothesis

Answer 8

chemo concentration given for a defined period of time and kills a constant fraction of the cells independent of the number of cells. repeated doses must be given to reduce size of the tumour.

Question 9

where is intravesical chemo applied

Answer 9

into the bladder

Question 10

list chemo side effects

Answer 10

fatigue
loss of appetite
pain
sore throat
hair loss

Question 11

bone marrow suppression consequences of a patient on chemo

Answer 11

anemia
leucopenia
thrombocytopenia
neutrophil suppression

Question 12

list radiotherapy side effects

Answer 12

skin problems
fatigue
more localised so dependent on area receiving radiation

Question 13

why is a patient likely to seem CAM

Answer 13

collaborative
congruence
autonomy
natural
dissatisfaction
society/ culture

Question 14

what characteristics does a medication need to have in order for cytotoxic precuations to be applied for staff safety

Answer 14

carcinogencity
teratogenicity
developmental toxicity
reproductive toxcity

Question 15

list 4 oncological emergencies

Answer 15

1. Neutropenic sepsis
2. spinal chord compression
3. tumour lysis - hypercalcemia
4. superioir vena cava obstruction

Question 16

what should you do if you suspect a pt has neutropenic sepsis

Answer 16

MET, broad spectrum, fluids, investigate, atbx change if not working

Question 17

describe tumour lysis syndrome

Answer 17

metabolic disturbance
sudden injury or death of cancer cells generally 3 days post chemo
damaged cell release there intracellular components

Question 18

what 4 disturbances does TLS cause

Answer 18

hyperuricaemia, hyperkalemia, hyperphosphatemia, hypocalcamia

Question 19

what medication that is originally commenced should be changed to what when TLS is confirmed

Answer 19

allopurinol to rasburicase

Question 20

symptoms of SVCO

Answer 20

swelling of face, neck, arms
periorobital oedema
dyspnea
reduced perfusion

Question 21

what calcium level in considered high

Answer 21

above 2.6

Question 22

how is bisphosphonate therapy the treatment post hypercalcemia as a maintenance drug

Answer 22

prevents the further bone breakdwon which promotes remodelling and reabsorption