week 3 cards Flashcards

(75 cards)

1
Q

allocortex

A

3 layered; e.g. hippocampal formation and olfactory cortex

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2
Q

isocortex

A

6 layered

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3
Q

mesocortex

A

3-5 layers

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4
Q

cortex formed from the medial pallium

A

archicortex; next to oldest cortex (e.g. hippocampal formation)

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5
Q

cortex formed from the lateral pallium

A

paleocortex; oldest (e.g. olfactory cortex)

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6
Q

formed from the dorsal pallium

A

neocortex (synonymous with isocortex)

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7
Q

pyramidal cells (basic structure and function)

A

pear-shaped soma and a single apical dendrite as well as a basal rosette of dendrites; the dendrites contain spines; projection neurons - axons project to deep white matter; can also project locally; excitatory, glutamate is primary NT

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8
Q

nonpyramidal cells

A

primarily GABA-ergic interneurons; multipolar or bipolar; e.g. chandelier, basket, neuroglia, and bipolar cells

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9
Q

spiny stellate cell

A

interneuron (locally projecting) that uses glutamate as its transmitter; located in layer IV of cortex; contains dendritic spines

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10
Q

basket cells

A

non-pyramidal cells in layers II, III, and V; multipolar and axons have “basket shaped” terminations that surround pyramidal cell soma

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11
Q

chandelier cells

A

non-pyramidal cells; axonal terminations contact the initial segments of pyramidal neurons

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12
Q

bipolar cells

A

non-pyramidal cells that have long dendrites and axons that are vertically oriented axons; tend to innervate more distal dendrites of pyramidal neurons

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13
Q

pyramidal cells of layers II and III

A

main source of cortico-cortical connections, including association fibers that project ipsilaterally and commissural projections that cross corpus callosum to the equivalent area on the opposite side; also send some axons to the sub cortex (esp. basal ganglia)

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14
Q

Layer V pyramidal neurons

A

main output of cortex; more superficial neurons in V are thinner with a smaller apical dendrite and project to the contralateral cortex and subcortical telencephalic targets; deeper neurons in V are robust and project beyond the telencephalon

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15
Q

layer VI pyramidal neurons

A

project to the thalamus; basis for thalamocortical rhythms, which are responsible for sleep-wake cycle regulation and consciousness; absence = epilepsy

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16
Q

primary motor cortex

A

area 4; pre central gyrus

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17
Q

primary somatosensory cortex

A

areas 3, 2, 1; post-central gyrus, superior parietal lobule

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18
Q

primary visual cortex

A

area 17; banks of calcarine fissure

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19
Q

primary auditory cortex

A

areas 41 and 42; transverse gyrus (Heschl’s)

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20
Q

premotor association area

A

area 6

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21
Q

somatosensory association area

A

areas 5 and 7 of the superior parietal lobule

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22
Q

areas 3a and 2

A

receive inputs from muscle afferents

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23
Q

areas 3b and 1

A

receive cutaneous inputs

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24
Q

parietal association cortex

A

attention to the internal and external environment;

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25
pluvinar projects to the...
parietal and occipital association cortexes
26
lateral posterior nucleus of the thalamus projects to the...
temporal association cortex
27
medial dorsal nucleus of the thalamus projects to the...
prefrontal association cortex
28
temporal association cortex
recognition and identification
29
prefrontal association cortex
executive function; [RIO] Restraint of inappropriate actions, Initiative to pursue productive actions, and Order (planning)
30
corticomedial amygdaloid nuclei function
olfaction
31
central amygdaloid nuclei function
principal output nucleus, important for autonomic control; principal cell is medium spiny GABAergic neurons; high density of DA containing axons
32
basolateral nuclei function
principal input nucleus; associated with neocortex and thalamus; largest, best-differentiated nucleus in humans; principal neurons are pyramidal (glutamatergic)
33
corticomedial amygdaloid nuclei inputs and outputs
input: olfactory bulb, VM and MD of thalamus output: hypothalamus via stria terminalis and olfactory bulb
34
central nucleus of amygdala inputs/outputs
inputs: basolateral nuclei of amygdala and hypothalamus output: brain stem and hypothalamus (autonomic) and midline thalamic nuclei (arousal)
35
basolateral nuclei inputs/outputs
input: many areas of association cortex and olfactory cortex output: central nucleus of amygdala, hypothalamus, entorhinal cortex and subiculum
36
bilateral lesions of the amygdala
hypersexuality, tame/placid, hyper- or hypophagia, orality
37
Kluver-Bucy syndrome (bilateral loss of anterior temporal lobe)
hypersexual, overly oral, tame, hyperphagia, hyperactive, psychic blindness
38
integration of emotional behavior and sensory experience
basolateral amygdala
39
aphasia
loss of ability for spoken and written language
40
alexia
loss of the ability to read when no visual impairment exists
41
agraphia
loss of ability to write when no motor impairment exists
42
paraphasia
language errors due to word or sound substitution
43
semantic paraphasia
substitution of one word for another (e.g. fork for spoon)
44
phonemic paraphasia
substitution of one sound for another (e.g. moon for spoon)
45
neologism
creation of meaningless words (e.g. soon for spoon)
46
semantics
meaning or interpretation of a word/language form
47
prosody
ton, inflection, volume of words and sentences that add meaning to language
48
dominant hemisphere in language function
left
49
wernicke's area
area 22; sensory speech area - correct usage of words to express thoughts
50
broca's area
areas 44 and 45; motor speech area - movements required to produce speech
51
peri-sylvian fibers
connect Wernicke's and Brocas
52
broca aphasia
expressive or motor aphasia; non-fluent speech, difficulty with syntax, grammar, and production of individual words; reduced verbal output; comprehension is intact but there may be difficulty understanding complex syntax; repetition is poor; limited use of syntactical words (e.g. adverbs, prepositions etc.)
53
Wernicke aphasia
receptive or sensory aphasia, fluent speech, syntax, and grammar, and structure of words is intact; verbal output normal or increased; noticeable absence of nouns; comprehension seriously impaired; produces nonsensical words and phrases (neologism)
54
conduction aphasia
difficulty repeating words, both comprehension and production of language are intact
55
left hemisphere language functions
lexical and syntactic language, writing, and speech
56
right hemisphere language functions
emotional coloring of language (prosody); rudimentary speech
57
global aphasia
both expressive and receptive language function are impaired; confluent, common paraphasic errors (word or sound substitution); lesion involves large area of the left hemisphere
58
conduction aphasia
comprehension and fluency are relatively good, repetition is poor; paraphasic errors are common (word or sound substitution); lesion location in the supra marginal gyrus and arcuate fasciculus
59
transcortical motor aphasia
similar to Broca's (non-fluent, able to comprehend) except subjects are able to repeat; lesion is in the left anterior frontal lobe, superior or inferior to Brocas area
60
transcortical sensory aphasia
similar to wernicke's (fluent, not able to comprehend) except that subjects are able to repeat; lesion is in the border zone between the left middle cerebral and posterior cerebral arteries
61
mixed transcortical aphasia
similar to global aphasia (non-fluent, unable to comprehend) except subjects are able to repeat; lesion at the border between left MCA and ACA
62
anomic aphasia
poorly defined because all aphasia have naming difficulty;; lesion location may be anywhere in language area
63
gerstmann syndrome
anomia, alexia, agraphia, right-left disorientation, acalculia, finger agnosia, lesion localized to left angular gyrus (area 39)
64
subcortical aphasia
lesions of the left basal ganglia or thalamus by be associated with variable forms of aphasia
65
alexia without agraphia
inability to read but preserved ability to write; lesion location is left medial occipital and medal temporal lobe involving the splenium of the corpus callosum
66
main input and output from dentate gyrus (of hippocampus)
input: from entorhinal cortex to granule cells (excitatory) output: to CA3 pyramidal cells (excitatory)
67
almost all inputs to the hippocampus are via the...
entorhinal cortex
68
almost all outputs from the hippocampus are via the...
subiculum
69
perfornant path
ERC to dentate gyrus
70
alvear path
ERC to CA1
71
dentate gyrus to CA 3 is via...
mossy fibers
72
CA3 to CA1 is via the...
Schaffer collaterals
73
crucial for implicit memory function
basal ganglia and cerebellum
74
responsible for the emotional component of memory
basolateral nuclei of amygdala
75
storage and recall of long term memories
neocortex for storage, hippocampus for recall