Week 3 - Central and Nervous System

Answer 1

The main difference between ganglia and nuclei is that ganglia are clusters of nerve cell bodies in the PNS whereas nuclei are clusters of nerve cell bodies in the CNS

Question 2

cns

Answer 2

3. Recall the following information about the central nervous system. The:

a) principal organs of the system

the brain and spinal cord

b) general function of each organ

The brain is a complex organ that controls thought, memory, emotion, touch, motor skills, vision, breathing, temperature, hunger and every process that regulates our body.

Your spinal cord carries nerve signals from your brain to your body

Question 3

neauron

Answer 3

Neurons (also called neurones or nerve cells) are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles

Question 4

neurogila

Answer 4

neuroglia, also called glial cell or glia, any of several types of cell that function primarily to support neurons

Question 5

somaitc vs autonomic NS

Answer 5

The somatic nervous system is responsible for voluntary actions, namely the innervation of skeletal muscle. The autonomic nervous system is responsible for all involuntary actions, including smooth muscle contraction, glandular stimulation, and other functions.

Question 6

afferent vs efferent NS

Answer 6

The afferent or sensory division transmits impulses from peripheral organs to the CNS. The efferent or motor division transmits impulses from the CNS out to the peripheral organs to cause an effect or action

Question 7

cns vs pns

Answer 7

The central nervous system includes the brain and spinal cord, while the peripheral nervous system includes all of the nerves that branch out from the brain and spinal cord and extend to other parts of the body including muscles and organs

Question 8

cerebrum

Answer 8

a) location

the large upper part of the brain

b) number of hemispheres Two (left and right)

c) name of the fissure and associated tissues dividing the hemispheres corpus callosum helps allow the two hemispheres to communicate, a deep longitudinal fissure separates the two.

d) name and number of lobes per hemisphere 4 lobes (frontal, parietal, temporal and occipital)

e) general distribution of gray and white matter

40% gray and 60% white (white matter is deep)

f) descriptive terms related to the surface: Gyri- bumps ridges on the cerebral cortex Fissures- large furrow that divides the brain into lobes and also into the two hemispheres as the longitudinal fissure Sulci- a shallower groove that surrounds a gyrus

g) name of the largest commissural tract that connects the gyri in one cerebral hemisphere to the corresponding gyri in the other hemisphere

The corpus callosum

Question 9

cerebral cortex

Answer 9

a) type of matter

Gray matter

b) location

Outermost of the cerebrum

c) thickness

About 2.5mm

d) surface appearance

Indentated and grooved

Question 10

4 lobes

Answer 10

frontal

a) the location

Front of the brain

b) the type of matter composing each

white

c) the function(s) in sensation and in movement

Initiates motor impulses to specific somatic effectors of system (i.e.,skeletal muscle) (in Primary motor area) Control voluntary movements of walking, talking, running, writing (in Premotor area)

Paritral

a) the location

Midbrain towards the top

b) the type of matter composing each

white

c) the function(s) in sensation and in movement

1. Awareness of general sensations of pain, pressure, temperature, touch, sense of position conscious proprioception. 2. Awareness of taste. Receive impulses Localization/intensity – in primary somatosensory area. Integration-perception-in somatosensory association area

Temporal

a) the location

By your ears/temples

b) the type of matter composing each

white

c) the function(s) in sensation and in movement

Awareness of sound and smell Receive impulse Integration-perception

Occipital

a) the location

Towards the back of your head

b) the type of matter composing each

white

c) the function(s) in sensation and in movement

Awareness of vision Receive impulse Integration-perception

basal nuclei

a) the location

Base of brain

b) the type of matter composing each

4 clusters of neurons, or nerve cells

c) the function(s) in sensation and in movement

Assist with coordination of voluntary skeletal muscle movement by controlling associated subconscious movements which accompany voluntary activity

Question 11

thalamus

Answer 11

• major relay station for seensory tracts
• crued interpretation of general sensations (pain, temp, touch)
  
  • helps with emotionsa by assoicatinf senesory impulses with feelings of pleasantneess or unpleastness (limbic)
    
    • role in arousal or altering mechanism (RAS)

Question 12

hypothalamus

Answer 12

• helps miantain waking state (RAS)
• emotions of rage/aggression (limbic)
• detetctions of changes in the internal enironment
  
  • temp via thermorecpetors
  • ecf osmotic pressure via osorecpetors

motor:

• major control centre of ANS: regulates activitesof viseral in effectors of system (thirst, appeitie)
• relay station from cerebral cortex to lower control centres in brainstem and spinal cord basis for central cortex infeluence over somatic and viscerak effector organ system
• anatomic connection with pituatioty gland- linking nervous/ endocrine control

Question 13

brainstem

Answer 13

• conduction pathway from spincial cord to cerebrum
• relay station from cranila nerves to toher parts of brain
• contains (RAS) (sanll areas of grey matter)- function to arouse, alert cortex and hence maintain consious
  
  • reflex centre for craniak nerves (pupil diluations)

Question 14

midbrain

Answer 14

• in brainstwm
  
  • control centre- reflex centre- for head and eyeball movements in reponse to sound and sight impulses

Question 15

pons

Answer 15

in brainstem

control centre- pontine rspirartory group- for regulation of rhythm of respirations

Question 16

medulla oblongata

Answer 16

• brainstem
• vital control centres: cardiac- regulates HR& dtrength of contraction vasometer- regulates blood vessel diameter. repitarory- regulates rate and depth of respiration
• non vital control centres: shallowing, vomiting, coughing, sneezing, hiccoughing
  
  • decussation of major motor projection tracts to skeletal muscle effectors

Question 17

cerebellum

Answer 17

• acts aubconsciously with cerebral cortex ro prodcue skilled coordinated skeeltal muscle movements
• maintainces of posture/balance

Question 18

Discriminate between the role of the thalamus and general sensory area of the cerebral cortex in the perception of sensation

Answer 18

The cerebral cortex is where these sensations are formed and perceived, but the thalamus has a lot of the sensory tracts and interpretation aspects that the cerebral cortex lacks

Question 19

functions of theses definations realting to skeltal muscles, cerebellum,basal nuclei, frontal lobe

Answer 19

i) frontal lobe

Initiates motor impulses to specific somatic effectors of system in the primary motor cortex

ii) basal nuclei

Assist with coordination of voluntary skeletal muscle movement by controlling associated subconscious movements which accompany voluntary activity

iii) cerebellum

Acts subconsciously with the cerebral cortex to produce skilled, coordinated skeletal muscle movements.

Question 20

RAS

Answer 20

Helps maintain waking state (hypotalamus)

Role in arousal or alerting mechanism (thalamus)

functions to arouse, alert cortex and hence maintain consciousness (brainstem)

Question 21

Limbic

Answer 21

Helps with emotions by associating sensory impulses with feelings of pleasantness or unpleasantness (thalamus), Emotions of rage, aggression (hypthalamus)

Question 22

cerebralspinal fluid

Answer 22

a) source of fluid

choroid plexus in the lateral, third and fourth ventricles

b) site and mechanism of formation

Cerebrospinal fluid is produced by a specialized tissue called the choroid plexus. Choroid plexuses are located in the walls of the lateral ventricles and in the roofs of the third and fourth ventricles. A choroid plexus shows numerous villi, via which it secretes the cerebrospinal fluid

c) site and mechanism of reabsorption (to include the superior sagittal sinus)

The majority of the cerebrospinal fluid (CSF) is absorbed into the venous system by the arachnoid granulations.The highest number of arachnoid granulations is found in the superior sagittal and transverse sinuses. Thus, these are the sites where most of the CSF is absorbed.

Answer 23

The main difference between ganglia and nuclei is that ganglia are clusters of nerve cell bodies in the PNS whereas nuclei are clusters of nerve cell bodies in the CNS

THE CEREBRUM

Question 24

3 branches into whic spinal nerves divide after leaving intervertebral foamina

Answer 24

a) dorsal ramus

The dorsal ramus carries information that supplies muscles and skin sensation to the human back.

b) ventral ramus

carry sensory and motor fibres for the innervation of the muscles, joints, and skin of the lateral and ventral body walls and the extremities

c) meningeal branch

The meningeal branches supply nerve function to the vertebrae themselves, including the ligaments, dura, blood vessels, intervertebral discs, facet joints, and periosteum

Question 25

circle of willis

Answer 25

anastomotic ring of arteries located at the base of the brain. ... The main function of the circle of Willis is to provide a collateral blood flow between the anterior and posterior arterial systems of the brain.

Question 26

obtaining cerebrospinal fluid

Answer 26

**a) name of test** spinal tap **b) level of vertebral column into which needle is inserted** L4/L3 **c) reason for needle insertion at the level identified (b)** Since the spinal cord ends as a solid structure around the level of the second lumbar vertebra (L2) the insertion of a needle must be below this point, usually between L3 and L4 **d) space into which needle is inserted to obtain fluid** subarachnoid space

Question 27

ceberocpinal fluid

Answer 27

**a) average volume in an adult and newborn** 4ml in adult, 2ml newborn **b) average pressure in an adult** **c) colour** clear/colourless **d) five constituents** CSF serves five primary purposes: buoyancy, protection, chemical stability, waste removal, and prevention of brain ischemia **e) three functions** CSF performs vital functions including: Support; Shock absorber; Homeostasis; Nutrition; Immune function

Question 28

spinial cord

Answer 28

**a) body cavity in which it lies** dorsal cavity **b) origin** The spinal cord extends from the foramen magnum to the sacrum in the human fetus at the beginning of the 2nd quarter **c) level of vertebral column at which it ends** The spinal cord tapers and ends at the level between the first and second lumbar vertebrae **d) two functions** It connects your brain to your lower back. Your spinal cord carries nerve signals from your brain to your body and vice versa.

Question 29

ganglia in PNS vs nuclei of CNS

Answer 29

The main difference between ganglia and nuclei is that ganglia are clusters of nerve cell bodies in the PNS whereas nuclei are clusters of nerve cell bodies in the CNS

Question 30

4 spinial nerves

Answer 30

**i) phrenic** **I:**cervical plexus **F:** receives innervation from the C3, C4, and C5 nerve roots **ii) radial** **I:** originates as a terminal branch of the posterior cord of the brachial plexus **f**:motor (movement) and sensory functions to the arm **iii) femoral** **I:** lumber plexus **F:** motor and sensory processing in the lower limbs **iv) sciatic** I: sacral plexus **F:** Motor function: Helps the muscles in your leg and feet move. Sensory function: Helps you feel sensations in your legs

Question 31

dermatome

Answer 31

A dermatome is an area of skin that's supplied by a single spinal nerve. Your spinal nerves help to relay sensory, motor, and autonomic information between the rest of your body and your central nervous system (CNS).

Question 32

sensory cranial nerves

Answer 32

**I (one) Olfactory** **F:** Transmits impulses from olfactory receptors **L:**olfactory bulbs **II (two) - Optic** **F:**Transmits impulses from retina. **l:**Thalamus **VIII (eight) - vestibulocochlear** **F:**Two branches: i. Cochlear – transmits impulses from Organ of Corti in ear. (Hearing) ii. Vestibular – transmits impulses from utricle and saccule. ( Equilibrium) **l:**Pons and Medulla (Vestibule Nucleus)

Question 33

mixed cranial nerves

Answer 33

**V (five) trigeminal** **F:**3 sensory branches: transmits impulses re: touch, pain, temperature from receptors in skin and mucous membranes of head, face, mouth, and tongue. Proprioceptive sensory axons from the extrinsic eye muscles. Stimulates muscles of mastication for control of chewing movements. (S) **L:** pons **VII (seven ) facial** **F:**Transmits impulses from taste receptors of anterior two-thirds of tongue. Stimulates: a. contraction of facial muscles for facial expression. (S) b. secretion of: i. lacrimal glands (production of tears) (A) ii. sublingual glands (production of saliva) (A) iii. submandibular glands (production of saliva) (A) **L:** pons **IX (nine) glossopharyneal** **F:**Transmits impulses from taste receptors of posterior onethird of tongue. Transmits impulses from baroreceptors and chemoreceptors in carotid sinus. Stimulates: a. contraction of muscles of pharynx swallowing (S) b. secretion of parotid gland saliva (A) **L:** medulla **X (ten) vagus** **F:** Transmits impulses re: pressure, pain, proprioception from receptors in: RESPIRATORY ORGANS: Larynx through Lungs DIGESTIVE ORGANS: Pharynx through Large Intestine HEART and AORTA Stimulates: a. skeletal muscle contraction in pharynx and larynx voice production (S) b. skeletal muscle contraction in pharynx, larynx and soft palate swallowing (S) c. smooth muscle contraction: i. bronchi bronchoconstriction (A) ii. digestive organs peristalsis, churning (A) iii. gastric gland secretion digestive enzymes and mucous (A) Inhibits cardiac muscle contraction decreased rate and force of contraction (A) **L:**medulla and pons

Question 34

motor crainal nerves

Answer 34

**III (three) Oculomotor** **F:** Stimulates contraction of: a. extrinsic eyeball muscles – movement of eyeball and upper eyelid. (S) b. intrinsic eye muscles (A) i. ciliary muscles: accommodation of lens ii. iris: const **L:**midbrain **IV (four) trochlear** **F:** Stimulates contraction of extrinsic eyeball muscles - movement of eyeball. (S) **L:**midbrain **VI (six) abducens** **F:**Stimulates contraction of extrinsic eyeball muscles - movement of eyeball. (S) **L:**pons **XI (evelen) accessory** **F:** Stimulates contraction of sternocleidomastoid and trapezius muscles head movements. (S) **L:**pons **XII (twelve) hypoglossal** **F:**Stimulates contraction of muscles of tongue speech and swallowing. (S) **L:** pons

Question 35

3 integratingy functions of cerebreum

Answer 35

Sleep and wakefulness (part of Reticular Activating System) Emotional responses (part of Limbic System) Memory, cognitive processes

Question 36

paritenal lobe somatosensroy area

Answer 36

**a) The primary somatosensory area is located in the postcentral gyrus of the parietal lobe. State the following:** **i) function related to reception of nerve impulses from sensory pathways** Awareness of taste. **ii) describe the somatic sensory map of the postcentral gyrus** Receive impulses Localization/intensity – in primary somatosensory area. Integration-perception-in somatosensory association area **b) The somatosensory association area is located posterior to the post central gyrus of the parietal lobe.** **i) function related to integration, perception and memory** The postcentral gyrus is a prominent gyrus in the lateral parietal lobe of the human brain. It is the location of the primary somatosensory cortex, the main sensory receptive area for the sense of touch.

Question 37

frontal pre frontal cortex

Answer 37

**a) List examples of functions of the prefrontal cortex.** Initiates motor impulses to specific somatic effectors of system (i.e.,skeletal muscle) **b) List examples of possible effects due to bilateral damage to the prefrontal cortices** Not getting the impulses to skeletal muscles, which means no voluntary movement **c) See Appendix IV which:** **i) Describes two types of changes occurring in the adolescent brain related to the prefrontal cortex.** **ii) What are the implications of these findings?**

Question 38

primary motor centre - frontal

Answer 38

**a) The primary motor area is located in the precentral gyrus of the frontal lobe. State the following:** **i) function related to controlling contraction of specific skeletal muscle groups.** Control voluntary movements of walking, talking, running, writing **ii) describe the somatic motor map of the precentral gyrus** The somatic motor pathways of the brain and spinal cord are divided into pyramidal and extrapyramidal systems. Both these systems control the motor activities of body through lower motor neurons. **b) The premotor association area is located immediately anterior to the primary motor area. State the following:** **i) function related to integration, initiation and memory of complex learned motor activities** Without the initiation and integration of these impulses, there would be no organisation within the motor activities, making it harder to do complex/simple tasks

Question 39

cerebralspinal fluid cells

Answer 39

ependymol cells - Ependymal cells are ciliated-epithelial glial cells that develop from radial glia along the surface of the ventricles of the brain and the spinal canal. They play a critical role in cerebrospinal fluid (CSF) homeostasis, brain metabolism, and the clearance of waste from the brain. * ventricles (3,4, lateral) * aqauducts (cerebral aquaduct) * both spinal cord * noursih/protect brain * senseory cortex (dorsal) partiental * motor cortex (frontal) ventral - premotor cortex (voluntary movement)

Question 40

central suclus

Answer 40

sperates frontal/parital

Question 41

fibre vs tract, neron vs nerve

Answer 41

fibre- nervous pathway in PNS, tract- nervous pathway in CNS Neuron - 1 nerve cell nerve- bundle of nerve cells (has blood supply)

Question 42

DCML pathway

Answer 42

The dorsal column-medial lemniscus pathway (DCML) is a sensory pathway of the central nervous system. It conveys sensation of fine touch, vibration, pressure, two-point discrimination and proprioception (position) from the skin and joints three neurons invloved: * 1 order(sensory) - senses touch, vibration, recpetor to brainsteam. peripheral system to medulla oblongata * 2nd order (integration station)- medulla- thalamus * 3rd order- thalamus to partiental lobe (sensory cortex) arms vs leg * 1st order sensory info goes from upper body snapses with 2nd order neauron at region called the curetus (fasicules) * if it is the legs/lower body, the region will be called guallilis (fasicules)

Question 43

corticospinal tract

Answer 43

The Corticospinal tract (CST), also known as the pyramidal tract, is a collection of axons that carry movement-related information from the cerebral cortex to the spinal cord. It forms part of the descending spinal tract system that originate from the cortex or brainstem. * motor pathway * motor cortex * done use ½/3 order nuerons (only sensory pathways) * upper/lower motor neuron * decussate (cross over) info from left to right and vis versa

Question 44

astrocytes

Answer 44

* most abundant, versatile, and highly branched glial cells * cling to neurons, synaptic ended and capillairies functions * support/brace neurons * play role in exchanges between capillaries and neaurons * guide migration of young nervous * control chemical enironment around neaurons * respond to nerve impulses and neaurotransmitters * inflence neauronal functioning - partipate in information processing in brain

Question 45

mircoglial cells

Answer 45

* small, ovoid cells with thorny processes that touch and monitor neaurons * migrate towards injured nearuons * can transform to pagocytize mircoorganism and neuronal debris

Question 46

oligodendrocytes

Answer 46

branched cells processes wrap CNS nerve fibres, forming insulating myelin sheaths thicker nerve fibres

Question 47

pyramidal tracts

Answer 47

These tracts originate in the cerebral cortex, carrying motor fibres to the spinal cord and brain stem. They are responsible for the voluntary control of the musculature of the body and face

Question 48

extrap'yramial tracts

Answer 48

These tracts originate in the brain stem, carrying motor fibres to the spinal cord. They are responsible for the involuntary and automatic control of all musculature, such as muscle tone, balance, posture and locomotio