week 4 Flashcards

(46 cards)

1
Q

whats the 4 primary tissue types

A

epithelium
connective tissue
nervous tissue
muscle

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2
Q

whats nervous tissue

A

intervnetal communication (brain, spinal cord and nerves)

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3
Q

whats muscle tissue

A

contracts to cause movement
muscles attached to bones (skeletal)
muscles of heart (cardiac)
muscles of walls of organs (smooth) INVOLUNTARY

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4
Q

whats epithelial tissue

A

form boundaries between different environments.
protects, secretes, absorbes, filters
skin surface

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5
Q

whats connective tissue

A

supports, protects, binds tissue together

bones, tendons,

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6
Q

where are the four primary tissues in the skin

A
  1. Stratified squamous epithelial tissue in the epidermis
  2. Connective tissue in the dermis
  3. Smooth muscle tissue in arterioles and attached to hairs (arrector pili)
  4. Nervous tissue in nerves
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7
Q

whats skin also called

A

integument

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8
Q

what s the three lakers of skin

A
1. Epidermis
• outer epithelial layer
2. Dermis
• a deep supporting layer of dense
connective tissue
3. Hypodermis
• subcutaneous layer composed of loose connective & adipose tissue
-  connective tisse, insulate and protect tissue underneath
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9
Q

whats stratified mean

A

lots of layers

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10
Q

whats squamous mean

A

flattened

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11
Q

whats the epidermis

A
  • outer layer
  • avascular
  • oxygen and nutrients diffuse from the blood vessels of the dermis
  • constants renewal replaced every 25-45 days
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12
Q

the process of creating new epiderms

A

cells move from the deepest layer of epidermis to more superficial layer, they flatten, produce large amounts of keratin (tough, waterproof protein) and eventually die

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13
Q

whats the most superficial and deepest later of the 5 epidermal layer

A

stratum corner: dead keratinised flattened cells

stratum basale:alive, needs access to oxygen and nutrients otherwise they will die

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14
Q

what are keratinocytes

A

produce keratin

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15
Q

what are melanocytes

A

produce melanin

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16
Q

whats the dermis

A
consists of connective tissue
cells include macrophages and fibroblasts which produce collagen and elastic fibbers to provide strength and flexibilty
contains:
- blood vessles
- lymphatic vessels
- nerves and sensory receptors
- sweat glands
- hair follicles
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17
Q

whats thick skin

A

covers palms, fingertips and soles off feet

  • very thick epidermis
  • lacks hair and oil glands
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18
Q

whats thin skin

A

covers rest of body

  • has hairs, sweat and oil glands
  • allows suppleness and agilty
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19
Q

does thick of thin skin heal quicker after an injruy

A

Injury where there are lots of hair, sweat glands, oil glands will heal quicker. Eg scull
THIN SKIN

20
Q

6 major functions of the skin

A
  1. Protection a.Chemical
    b. Physical
    c. Biological
  2. Sensation
  3. Metabolic function
  4. Blood reservoir
  5. Excretion
  6. Temperature regulation
21
Q

how does the skin profile protection

A

chemical barrier:
- acidic outside of skin
- dens inis (natural antibiotic) secreted by skin cells to kills bateria
- melanin protects DNA in underlying cells from UV damage
Physical barrier:
- keratin and oily secretions block most water from entering/ leaving body
Biological barrier:
- macrophages engulf and dispose of viruses and bacteriaa that manage to penetrate the epidermis

22
Q

how does the skin provide sensation

A

pain receptors: nocieptors
temperature receptors: chemoreceptors
touch, pressure and vibration receptor: mechanorecpetos

23
Q

how does skin have metabolic function

A

synthesis of vitamin D precursor

24
Q

how does skin have blood reserviour

A

can hold up to 5% of body bloods volume

25
how does skin ecretion
• Nitrogenous wastes and salt are excreted in sweat
26
how does skin regulate temperature
``` increase in temperature leads to: - dilation of vessles - increase sweat gland activie decrease in temperature leads to: - contrictin of precapiliary sphincters to minimise heat loss to external environment TEMPERATURE MONITORED BY thermorecpetors ```
27
what does minor wounds invole
just epidermis
28
what does major wounds involve
both epidermis and dermis
29
skin repair two processes
regeneration | fibrosis
30
whats skin repair regeneration
* replaces destroyed tissue with the same kind of tissue can be restored to normal if: * damage is minor and involves just the epidermis * epidermis has stem cells to regenerate lost tissue
31
what skin repair fibrosis
• replaces destroyed tissue with scar tissue • damage that includes the dermis leads to repair by fibroblasts • scar tissue does not have any of the same qualities as the tissue before the injury
32
whats the three stages of skin repair
Stage 1. Inflammation: formation of blood clot Stage 2. organisation or proliferative stage: formation of granulation tissue Stage 3. maturation: regeneration and fibrosis
33
stage 1 of skin repair
inflamation Function: prepare the wound for repair, eliminate invading organisms and remove foreign tissue. damaged blood vessels release inflammatory chemical (mechrophasges) clotting proteins produce a blood clot to stop from blood loss
34
stage 2 skin repair
orginsation or proliferation stage Function: to synthesise ECM including collagen and restore a blood supply - blood clot replaced by granulation tissue )bring oxygen and nutrients required for healing) - fibrolasrts produce collagen fibres that bridge the gap - epithelial stem cells multiply and migrate over the granulation tissue
35
stage 3 skin repair
maturation - collagen laid down contracts to pull wound edges together - existing blood vessels are compressed so the scar is avascular MINOR WOUND: epithelial stem cells newr wound site divide and growunder scuba and regenerate epithelium, scab falls off and skin reflects preinjury tissue (will have underlying scar tissue) MAJOR WOUND: scar tissue visible repair prodominately by fibrosis (has no elasticity or flexibility, no hair or sweat glands)
36
skin damage due to Bruns
- may lead to tissue damage, denture proteins, cell death - looks of skin function - immediate threat due to dehydration and electrolyte - infection via bacteria
37
burn classification
* 1st degree - Superficial burn * 2nd degree - Partial- thickness burn • Superficial partial-thickness burn • Deep partial-thickness burn * 3rd degree - Full-thickness burn • 4th degree - Subdermal burn
38
1st degree: superficial burns
- confined to the epidermis - no barrier functions altered - maybe painful - general heals by itself in less than a week without scarring - sunburn
39
2nd degree burn: superficial partial thickness burn
- destruction of entire epidermis and no more than a third of dermis - vessels injured - epidermis lifts off and causes blisters - most painful burns because nerve ending in skin are exposed - remming blood low is adequate and infection risk low - heal within 1-3 weeks
40
2nd degree deep parital thickness burns
- destruction of epidermis and most of dermis - dead tissue (NO BLISTERS) - wound appears white and dry - blood flow compromise - vulnerable to infection - reduced pain because nerve endings have been destroyed - would heal over 3 weeks
41
3rd degree full thickness burn
- complete destruction of epidermeris and dermis - results significant scarring - generally require a skin graft - no painful initaitlla - appearance can be any colour
42
4th degreee: subnormal burns
- compete destruction of epidermis and dermis - would appears charred,, dry and brown or white without sensation teatime often requires ampuation
43
whats primary concern for burns and then secondary
fluid loss | then infection
44
why do full thickness burns require skin graft
would take too long to heal by itself (open up to infections) therefore skin grafts used
45
whats hypertrophic burns scares
scar with excessive collagen synthesis, leading to a raised or thickened area but contained within the wound margin - are more prominent around joints where skin tension and movement are high (would impact on ROM)
46
burn scar contractors
pathological result of long term shrinkage of a scar • results in the inability to perform full range of motion of a joint treatments include: • Stretching • Splinting • Massage • Skin grafting • Silicon gels