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pharm > week 4 questions > Flashcards

week 4 questions Flashcards

1
Q

What do you do in the case of acute dystonia?
Bonus: which gen is more likely to cause this?

A

Administer diphenhyramine
1st gen is more likely to cause this

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2
Q

What to do in case of Parkinsonism?
Bonus: which gen?

A

administer anticholinergic med
1st

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3
Q

What constitutes “extra pyrimidal” side effects?

A

acute dystonia = face spasms
akathisia = restlessness
Parkinsonism

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4
Q

Explain tardive dyskinesia

A

difficulty speaking and chewing –> slow wormlike movements of mouth
late in therapy and untreatable
1st gen

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5
Q

Side effects of 1st gen vs 2nd gen antipsychotics

A

1st gen: extrapyrimidal side effects and prolactin elevation
2nd gen: agranulocytosis, anticholinergic, CYP3A4 metabolism

caveot: not exclusive, just more likely

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6
Q

What is neuroleptic malignant syndrome and how do you treat it?

A

rigidity, fever, and autonomic inability that happens with some psych meds

treat with dantrolene, IV fluids, and stop psych med

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7
Q

mild abstinence syndrome

A

happens when antipsychs are abruptly withdrawn
causes restlessness, insomnia, GI distress, and sweating

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8
Q

diagnosing schizophrenia

A

decrease in self care
1 month of active phase symptom
6 month of continuous signs of disturbance

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9
Q

who SHOULDN’T take SSRIs?

A

patient with history of suicide attempt

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10
Q

what is serotonin syndrome

A

happens when 2 meds affecting reuptake of serotonin are taken at same time
***DONT TAKE SSRI AND MAOI W/IN 5 WEEKS

delirium, tachycardia, hyperreflexia, agitation, tramors, hyperthermia, seizures, dysrhythmias, DIC

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11
Q

Types of drugs to treat BPD

A

mood stabilizers = lithium, diva sodium, carbamazepine
antipsychotics
antidepressants

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12
Q

Things to be cautious ab with lithium

A

small therapeutic range
short half life
can’t be excreted if not enough sodium

Too musch = GI issues, tremors, hypothyroidism, renal issues

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13
Q

What do BPD ppl have to consider before getting pregnant?

A

they can’t be on lithium

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14
Q

lithium drug interactions

A

no diuretics
no NSAIDs
no Anticholinergics

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15
Q

What are benzos approved for? also what is their class?

A

they’re sedative hypnotics

used for seizures, sleep, and anxiety

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16
Q

Unique pros of benzos

A

don’t suppress REM
don’t increase metabolism of other drugs
Good for etoh withdrawal

17
Q

What to do in a benzo OD

A

give Flumazenil –> careful bc it causes withdrawal

18
Q

What can’t you ingest with benzos?

A

grapefruit and any other CNS depressors

19
Q

Which sedative/hynotic DOES NOT cause CNS depression

A

Ramelteon

20
Q

Barbituates mech of action

A

intensify GABA in brainstem

21
Q

what to do when barbiturate OD

A

airway
fluids
pressor support
activated charcoal

22
Q

Amphetamine mech of action

A

release NE and dopamine

23
Q

Amphetamine tolerance, dependence, and abuse

A

Tolerance: eventually tolerat mood elevation, appetite suppression, and cardiovascular stimulation

Abstinence syndrome with abrupt withdrawal

can be abused bc of euphoria

24
Q

Amphetemine adverse effects

A

CNS stimulation
weight loss
CV effects
psychosis

25
Q

Methylxanthines

A

basically caffeine
used to promote wakefulness and for baby apnea

26
Q

Modafinil

A

keeps ppl awake –> narcolepsy, shift work, sleep apnea

fucks with oral contraceptives

27
Q

non stimulant to treat adhd

A

atomoxetine
once daily
inhibits NE reuptake

28
Q

A2 agonists for adhd

A

clonidine and guanfacine
might make kid sleepy and hypotensive

29
Q

antidepressants for adhd

A

tricyclic decrease hyperactivity

bupropion reduces behavioral symptoms –> seizure risk

30
Q

carbamezopine consideration

A

speeds metabolism of drugs like warfarin and oral contraceptives –> need to increase dose of these

***Anti epileptic that’s also weirdly good for BPD

31
Q

which drug class is most likely to cause Stevens-Johnson syndrome

A

Anticonvulsants/ antiepileptics

pharm (26 decks)

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