Week 5 Flashcards
(8 cards)
What are Glands/Hormones and Hypothalamus
Glands: Secrete hormones in the circulatory system in response to a stimuli
Hormones: Chemical substances secreted by glands in the circulatory system in response to a stimuli and creates a physiological response
Hypothalamus: Maintains homeostasis by regulating Autonomic nervous system and control the storage+secretion of hormones from pituitary gland
Hormone Functions
Protein Synthesis: Stimulates Protein Synthesis
Proliferation: Stimulates Mitosis and cell proliferation
Activation/Deactivation: Activates/deactivates enzymes
Methods of controlling Hormone release
Humoral Stimuli: Changing blood levels of ions and nutrients
Neural Stimuli: Nerve fibres stimulate hormone release
Hormonal Stimuli: Hormone release in response to hormones produced by other endocrine organs
Target Cells
Each target cell has a specific receptor for a particular hormone. If cell does not have the right receptor, it will not respond to that particular hormone
Factors Impacting Hormone release
Transport proteins: Transport hormones around circulatory system
Concentration (half-life): Time it takes hormones to decrease by half
Other Hormones:
-Permissive: Hormone enhances response of a target organ to another hormone
-Antagonistic Effect: Second hormone has opposite effect of initial hormone
-Synergistic effect: Two or more hormones working together to influence another hormone
Hypothalamus and Anterior Pituitary Gland
1.) Hypothalamic neurons secrete stimulating and inhibiting hormones into anterior pituitary gland
2.) Hypothalamic hormones stimulate release of hormones from anterior pituitary gland
3.) Anterior Pituitary hormones are secreted into blood vessels to be distributed throughout the body
Hypothalamus and Posterior pituitary gland
1.) Oxytocin and ADH are transported from he hypothalamus to the posterior pituitary
2.) They are stored in posterior pituitary
3.) When hypothalamic neuron fire, the stored hormones are released for distribution in the body
Hypothalamus and Thyroid
1.) When thyroid hormone levels are low, hypothalamus produces TRH
2.) TRH travels to and stimulates anterior pituitary to produce TSH
3.) TSH signals the thyroid to increase production of its hormones
4.) When thyroid hormones increase, signal to hypothalamus and anterior pituitary gland to decrease production of TRH and TSH to maintain appropriate levels of thyroid hormones (Negative Feedback Loop).