Week 6 Flashcards

(292 cards)

1
Q

Elimination

A

removal, clearance, or separation of matter

excretion of waste product

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2
Q

how does the human body eliminate waste

A

through skin, kidneys, lungs, and intestines

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3
Q

Bowel elimination

A

the process of expelling stool (feces)

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4
Q

a term used to describe the process of bowel elimination

A

defecation, defecate, or bowel movement

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5
Q

urine elimination

A

the process of expelling urine

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6
Q

what terms is used to describe urine elimination

A

micturition

urination

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7
Q

continence

A

the purposeful control of urinary or fecal elimination

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8
Q

impaired elimination

A

one or more problem associated with the elimination process

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9
Q

anuria

A

absence of urine

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10
Q

dysuria

A

painful urination

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11
Q

polyuria

A

multiple episode of urination (diabetes)

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12
Q

urinary frequency

A

multiple episodes of urination with little urine produced in a short period of time.

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13
Q

urinary hesitancy

A

the urge to urinate exists, but the person has difficulty starting the urine stream

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14
Q

Kidney’s role in elimination

A

removal of metabolic waste and other element from the blood in the form of urine

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15
Q

what is the role of the gastrointestinal tract in the process of elimination

A

responsible for the removal of digestive waste in the form of stool

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16
Q

urinary elimination involve what structures?

A

the kidney

ureters

bladder

urethra

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17
Q

main functional unit of the kidneys?

A

the nephron

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18
Q

nephron

A

the main functional unit of the kidney

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19
Q

what are the nephron composed of?

A

blood vessels and renal tubules

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20
Q

formation of urine involves what 3 processes

A

glomerular filtration

tubular reabsorption

tubular secretion

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21
Q

where does the blood enter the kidney?

A

renal artery then branches into smaller arteries, arterioles, and finally a cluster of capillary known as glomerulus

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22
Q

glomerulus

A

semi-permeable membrane that serves to filter the blood into a C-shape structure of the renal tubule know as the Bowman’s capsule

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23
Q

what represent the beginning of urine formation

A

glomerular filtration

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24
Q

what does filtrate contain

A

water

electrolyte

waste

all removed blood

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25
what does the filtrate pass through?
a sequence of renal tubules (Bowman's capsule to the proximal convoluted tubule, the loop of Henle, and the distal convoluted tubule.
26
where does the water in the filtrate gets absorb?
a network of capillaries surrounding the renal tubules reabsorb most of the water, electrolytes, and other necessary element back into the blood. also known as tubular reabsorption
27
tubular secretion
secondary process in which substances (potassium, hydrogen, ammonia, and drugs) moved from the blood in the capillaries surrounding the tubules into the tubules.
28
the amount of electrolytes reabsorbed into the blood or exreted int he renal tubules is controlled by what hormones?
aldosterone antidiuretic hormone parathyroid hormone renin atrial naturiuretic factor
29
after the renal tubules, where does the urine go?
moves into the collecting duct and then into the renal pelvis, the ureter, and the bladder where it is stored until urination occur
30
how many mL does the bladder hold in adults?
300 to 500 mL
31
what does pressure in the bladder stimulate?
stimulate stretch receptors in the bladder wall receptors send impulses through the spinal cord to signal the need for urination.
32
what prevents urine from leaking out of the bladder?
internal sphincter, composed of involuntary smooth muscle
33
external sphincter
located below the internal sphincter and surrounding upper urethra made of voluntary skeletal muscle
34
micturition reflex
cause the internal sphincter to relax and the bladder wall to contract. relaxation of the external sphincter, urine pass through the urethra.
35
continence
control of urinary control
36
what is the function of the gastrointestinal system?
breakdown and absorption of nutrient from food ingested and the elimination of waste in the process extends from mouth to the anus
37
what is the first part of the GI tract consist of?
mouth, esophagus, stomach, and small intestine involved in digestion and absorption of nutrients
38
what other organ is also included in digestive organ?
liver gall bladder pancreas
39
where does waste formation occur
in the colon
40
what are waste product called
stool or feces
41
what is waste product made of?
water bile undigested food matter unabsorbed mineral bacteria mucous epithelial cells from the lining of the intestine
42
what helps fecal matter move through the GI tract?
smooth muscle within intestinal tract stimulate peristalsis
43
how long is the large intestine?
5 or 6 feet long and 2 inches in diameter
44
how many part is the large intestine made of?
(4) cecum (appendix) colon rectum anus
45
what is the function of the large intestine?
absorb water and electrolyte as fecal matter move through its walls
46
what helps lubricate the walls in the intestine?
mucus help aid in expulsion of the stool if excessive peristalsis and stool move through quickly, less water is absorbed resulting in loose stool
47
defecation
process of expelling stool involves voluntary and involuntary muscle
48
at what age do children be able to identify the urge to urinate and defecate?
18 to 24 months
49
when are children ready to potty train
2-3 years
50
what age does renal bloodflow reduce?
80 years
51
how much is bloodflow reduced to in later years?
600mL
52
reason why nephron function is reduced to 50%?
change in the size of the kidney due to age and sclerosis absence of disease, reduction in renal reserve makes older adult more susceptible to electrolyte imbalace and kidney damage due to medications
53
what happen to bladder due to age?
bladder retains tone volume of urine decrease causing urine frequency urethra becomes weak, increase risk of incontinence
54
what happens to bowel due to age?
atrophy of smooth muscle layer in colon reduced mucous secretion reduced tone of internal and external sphincter reduced neural implulses, more susceptible to constipation or incontinence.
55
what contributes to urinary and GI function?
incontinence retention discomfort infection inflammation neoplasms organ failure
56
incontinence
loss of control of either urine or bowel elimination
57
what does incontinence lead to?
skin break down changes in daily activity, functional activity, and social relationship
58
urinary incontinence
disruption in the storage or emptying of the bladder with involuntary release of urine usually associated with dysfunction of the external and/or internal urinary sphincters
59
fecal incontinence
involuntary passage of stool and ranges from an occasional leakage of stool while passing gas to complete loss of bowel control
60
retention
unintentional retention of urine or stool associated with obstruction, inflammation, or ineffective neuromuscular activation within the bladder or GI tract
61
type of incontinent
stressed -leakage of small amount during physical movement urge-large amt unexpected at times, including sleep overactive bladder- frequency and urgency with or without urge incontinence functional- untimely urination because of physical disability, external obstacle, or cognitive overflow- leakage due to full bladder mixed- stress and urge incontinence together transient - leakage the will temporarily passed (infection or taking new med)
62
what happens as a result of constipation?
difficult passage of hard, dry stool loss of appetite discomfort fecal impaction
63
largest cavity in the human body?
abdominal cavity
64
what does the abdominal cavity contain?
1. stomach 2. small/large intestine 3. liver 4. gall bladder 5. pancreas 6. spleen 7. kidneys 8. ureters 9. bladder 10. adrenal glands 11. major vessels
65
what is the abdominal lining called
peritoneum
66
what is the peritoneum made of?
serous membrane forming a protective cover.
67
how many layers is the peritoneum divided into?
two: parietal peritoneum - lines abdominal wall visceral peritoneum - covers organs
68
what is the space between the parietal peritoneum and the visceral peritoneum called?
peritoneal cavity contains small amount of serous fluid to reduce friction between abdominal organs
69
what muscle is found in the anterior border of the abdomen
rectus abdominis
70
what is found on the posterior border?
the vertebral column and lumbar muscle
71
what provides lateral support to the stomach
internal and external oblique muscle
72
what muscle lies under the oblique?
transverse abdominis
73
Linea alba
a tendinous band that protect the midline of the abdomen between the rectus abdominis muscle. extends from xiphoid process to symphysis pubis
74
how long is the alimentary tract
27 feet
75
what does the alimentary tract include?
1. mouth 2. esophagus 3. stomach 4. small/large intestine 5. rectum 6. anal canal
76
what is the main function of the alimentary tract?
ingest and digest food absorb nutrients, electrolyte, and water excrete waste products.
77
peristalsis
controlled by ANS and wave-like movements that moves food along the digestive tract
78
where does the breakdown of carbs begin?
in the mouth
79
how long is the esophagus?
about 10 inches
80
what does the esophagus connect?
connect the pharynx to the stomach found posterior to the trachea
81
what is used to breakdown protein and fats in the stomach?
digestive enzymes and hydrochloric acid turns food into chyme and propels it to the duodenum
82
what is the pH of the stomach?
2.0-4.0
83
what regulates outflow of chyme into the duodenum
pyloric sphincter
84
what produce bowel sounds?
the movement of air and fluid through he stomach and small/large intestine.
85
what is the largest alimentary tract?
small intestine about 21 feet.
86
where does the small intestine begin and end?
pyloric orifice and the ileocecal valve
87
what are the 3 segment of the small intestine?
duodenum(1 foot), jejunum (8 feet), and ileum (12 feet) with pH of 6.0-7.4
88
how long is the large intestine?
5 feet
89
what is the large intestine consist of?
cecum appendix colon rectum anal canal
90
how many parts is the colon divided into
ascending colon transverse colon descending colon
91
what is the end of the colon called?
sigmoid colon
92
what connects the sigmoid colon and the pelvic floor
rectum with a pH of 6.7
93
where does the ileal content empty into?
the cecum (beginning of large intestine
94
what does the large intestine absorb?
water and electrolytes
95
what are the accessory organs of the GI tract?
salivary gland liver gall bladder pancreas
96
what is the largest organ in the body?
the liver which weighs 3.5 pounds and found under diaphragm divided into right and left lobe
97
what is the function of the liver?
1. bile production and secretion 2. production of clotting factors and fibrinogen 3. synthesis of most plasma proteins (albumin and globulin) 4. detoxification of a variety of substances, including drugs and alcohol
98
what is the function of the gall bladder?
store biles produced by the liver (found inferior of liver) the cystic duct combine with the hepatic duct form the common bile duct and drains into duodenum bile gives stool brown color
99
what is the function of the pancreas
endocrine secretion- release insulin, glucagon, somatostatin, and gastrin for carb metabolism exocrine secretion- bicarbonate and pancreatic enzyme that flow to duodenum.
100
what does lipase do?
break down fat
101
what does amylase do?
break down carbohydrate
102
what does protease do?
break down protein
103
what is the function of the spleen?
removal of old or agglutinated erythrocytes and platelets activation of B and T lymphocytes
104
what is the spleen made up of ?
white pulp - lymphatic nodules and diffuse lymphatic tissue red pulp -venous sinusoids
105
what does the urinary tract include?
kidneys ureters urinary bladder urethra
106
where are the kidneys located
posterior abdominal wall on either side of the body
107
what is the function of the kidneys?
secretion of erythropoietin to stimulate red blood cell production and production of a biologically active form of vitamin D nephrons regulate fluids and electrolyte balance through microscopic filter and pressure system to eventually produce urine.
108
what does antacid do?
neutralize acidity (hydrochloric acid) lower pepsin activity raise the gastric pH which inactivates pepsin
109
what are the 4 types of antacid?
non systemic antacid: aluminum compound magnesium compound systemic antacid: calcium compound sodium compound
110
what does accessive amount of sodium bicarbinate do?
cause metabolic alkalosis
111
what does excessive calcium carbonate do?
cause hypercalcemia
112
what does aluminum hydroxide do?
cause constipation
113
what does magnesium hydroxide do?
cause diarrhea
114
what is aluminum hydroxide's absorption?
minimal absorption through intestine in feces binds to phosphate; small amount in urine
115
where is calcium bicarbonate absorbed?
occurs mostly in duodenum and depends on calcitriol and vitamin D. Food increases absorption by 10-30%.
116
what does pepsin do?
cause mucosal damage.
117
what is a contraindication of antacid?
electrolyte imbalance renal failure GI obstruction due to antacide stimulating motility
118
contraindications and precautions for aluminum hydroxide?
contra: hypersensitivity to aluminum products and hypophosphatemia precaution: hepatic and renal disease, older adults, children and pregnancy
119
contraindications and precautions for Magnesium hydroxide?
contra: GI obstruction precaution: myasthenia gravis, renal impairment, diarrhea, and older adults
120
contraindications and precautions for calcium carbonate?
contra: none precaution: renal impairment, hypercalcemia, and hypothyroid disease
121
aluminum hydroxide dosage
adult 600-1200 mg PO QID between meals and at bedtime
122
magnesium hydroxide dosage
adult: 400-1200 PRN quid
123
Calcium carbonate
adult: 500-3000 mg PO prn
124
Absorption of glucocorticoid
depends on the route of administration intended to exert a localized effect in the lungs can cause systemic effects if swallowed minimal oral bioavailability of 1% fluticasone propionate has <1%, budesonide 11%, flunisolide 20% oral admin. absorption is rapid and nearly complete IM depends on glucocorticoid-some immediately while others longer time for absorption depends on the salt in which med is combined
125
destribution of glucocorticoids
highly protein bound, but depends on specific drug
126
metabolism of glucocorticoid
metabolized primarily by the liver, resulting are inactive
127
excretion of glucocorticoid
metabolite in renal
128
mechanism of glucocorticoid
exert antiinflammatory action to decrease asthma symptoms block luekotrienes, histamines, and prostaglandins block infiltration of esoinophils and leukocytes-mediator in inflammatory process reduce permeability to yield reduction in edema in the airway. reduce hyper activity and mucus production in the airway.
129
duration of glucocorticoid
depends on dosage, route, and drug solubility. IV determined by half life IM by water solubility-high solubility mean shorter duration; less solubility means longer duration fluticasone half life is 7.8 to 10 hours; onset and peak unknown. duration is 24 hours
130
Leukotriene modifier
need if glucocorticoid does no provide adequate symptom management
131
absorption of leukotriene
montelukast bioavailability is 64% oral zafirlukast is rapid-food decrease 40%; administered 1h AC or 2 hours PC zileuton is rapid with presence and absence of food
132
Distribution of leukotreine
montelukast high bound >99 to plasma protein zafirlukast is highly bound>99% to plasma protein zileuton is 93% bound to protein
133
metabolism of leukotriene
montelukast by hepatic cytochrome p450 enzyme zafirlukast undergo hepatic metabolism zileuton metabolize by liver
134
excretion of leukotriene
montelukast is excreted in bile zafirlukast is fecal excretion zileuton excreted in urine
135
leukotriene subclass
first is zileuton indirect mechanism that inhibit enzyme 5-lipoxygenase which leukotriene needs for synthesis second is montelukast zifirlukast directly bind to D4 leukotriene receptors in lungs and circulating immune cells. result induce inflam response- which prevent smooth muscle contraction of bronchial airway, reduce mucous secretion and decrease vascular permeability
136
pharmacodynamic profile of leukotriene
montelukast has 0.5 hours onset; 3-4 hours peak and last for 24 hours and has half life of 2.7 to 5 hours zafirlukast onset unknown; peak 3 hours; duration unknow and has 8-16 hours half life zileuton onset unknown; peak 1.7 hours and duration is 2.5 hours and half life unknown
137
beta2-adrenergic agonist
cause bronchodilation in chronic and acute asthma patient. short acting beta agonists/ long acting beta agonists/ oral beta agonists
138
most commonly used beta2-adrenergic agonist
albuterol - short acting beta2 adrenergic agonist salmeterol- long acting adrenergic agonist
139
absorption for adrenergic agonist
albuterol has 105-20% bioavailability when inhaled and low systemic levels salmeterol has little systemic absorption
140
distribution of adrenergic agonist
albuterol is unknown salmeterol is 96% protein bound
141
metabolism of adrenergic agonist
albuterol metabolize in gastointestinal tract by the enzyme sultia3 salmeterol is metabolize by hydroxylation with involvment by CYP3A4
142
excretion of adrenergic agonist
albuterol undergo renal excretion salmeterol is excreted in feces
143
when is beta2 adrenergic agonist used
short acting beta 2 adrenergic agonist is used in acute phase of asthmatic attack to reduce airway constriction and restore airflow long-acting beta 2 adrenergic agonist are used in the chronic management of airway symptoms
144
albuterol pharmcodynamic
has an immediate onset of action when inhaled. peaks at 10-25 min after administration and last 3-4 hours with a plasma half-life of 3-4 hours. dosed based on symptoms
145
salmerterol pharmacodynamic
salmeterol onset of action and peak plasma concentration depends on if the patient has asthma or COPD. asthma begins to work in 5-48 minutes peaking at 3-4.5 hours. salmuter half life is 5.5 hours and last for 12 hours. allowing for twice daily dosing.
146
anticholinergic type
short acting (Ipratropium) and long acting choloinergic (tiotropium)
147
absorption of anticholinergics
Ipratropium-after inhalation is deposited in the GI tract and lungs. drug is quaternary amine so it does not readily absorb in systemic circulation Tiotropium-after inhalation bioavailabilty is 19.5%
148
distribution of anitcholinergic
Ipratropium is minimal protein bound tiotropium is protein bound
149
metabolism of antiholinergics
ipratropium undergo partial metabolism to inactivate ester hydrolysis product tiotropium metablism is minimal. fraction of drug ungergoes CYp 450 oxidation and glutathion conjugation
150
excretion of anticholinergic
Ipratropium from IV admin is in urine Tiotropium is mainly in urine
151
Theophylline
class of drug known as methyxanthine, including caffeine sustained release is slow but plasma level is stable than the immediate release. absorption is affected by food 40% prtoein bound metabolize in liver; half life in plasma varies half life of theophylline is excreted in adults unchanged and in noenate only 10% unchanged. which requires careful monitoring blood level monitored. dosage adjusted level for peds is 5 and 15mcg/mL and adults 10 and 20 mcg/mL therapeutic is narrow.
152
Therapeutic use of Theophylline
used with chronic stable asthma with inadequate symptom improvement of other treatment modest bronchodialtor effect in stable COPD and may be combined with beta 2 agonist for greater clinical effects.
153
Mechanism of Theophylline
relax bronchial smooth muscle to yield bronchodiolation. suppress airway stimuli and increase contractual force of diaphragm muscle. onset is unknown. peaks at 1-2 hours half life of 7-9 hours and last for 12 hours
154
epigastrium
pancreas
155
umbilical
small intestine
156
hypogastric
bladder, uterus
157
right hypochondriac
liver, glass bladder
158
left hypochondriac
spleen
159
right lumbar
ascending colon
160
left lumbar
descending colon
161
right inguinal
overy, ureter, appendix
162
left ingunal
overy, ureter
163
what is used to ascultate the abdomen
the diaphragm for frequeny and character of bowel sounds
164
what are the liver and spleen auscultated for?
friction rub
165
what is the bell of the stethoscope used for?
vascular sounds, including bruits and venous hums
166
when inspecting the abd, which surface characteristics would the nurse observe?
striae lesions and scars tautness venous return
167
which region of the abdomen would the nurse palpate the pancreas
epigastric
168
om auscultation, which elements of a patient's bowel sound should be assessed
frequency and character
169
over which abdomen structure should the nurse auscultate for friction rubs
liver spleen
170
ascites
presence of fluid
171
percussion is used to assessed what element of abdominal examination
1. size and density (liver, spleen, kidneys, gastric bubble) 2. presence of ascites 3. presence of gatric distention (air) 4. presence of fluid-filled or solid masses
172
why do the nurse palpate abdomen for
temperature texture presence of masses vascular thrills
173
what does the nurse palpation assess for
location size shape consistency tenderness pulsation mobility movement with respiration
174
what organ can be felt as masses
liver gallbaldder spleen left and righ kidneys aorta urinary bladder
175
light palpation
texture of skin presence of masses tenderness muscle rigidity use palmar surface of fingers and depressing the abdominal wall 1 cm with light, even, circular motion
176
moderate palpation
abdomen is soft or rigid reveals presence of tenderness use palmer surface of fingers
177
deep palpation
used to palpate liver differentiate abdominal organs from pathologic masses bimanual technique used, exerting pressure with the top of the hand and concentrating on sensation with the bottom hand
178
palpate around umbilicus
umbilical rign is incomplete or soft in center
179
palpate the liver
is edge palpable and repeat medially and laterally to the costal margin
180
palpate gallbladder
below margin at the lateral border of the rectus abdominus muscle for tenderness in the area.
181
palpate spleen
place right hand on the abdomen below the left costal margin and gently pressing fingertips inward while the patient take a deep breath. patient lying on the right side and hip and knee flexed
182
palpate kidneys
place hand over flank, then place other hand at the coastal margin. while patient exhales, the nurse should elevate the hand on the flank and palpate deeply with the other hand palpate for texture and character of kidneys tenderness in the flank area
183
palpate the bladder
done over suprapubic area for distention and tenderness
184
palpation of aorta
palpate left of midline, feeling for aortic pulsation alternate - place palmer surface of hand on the midline and press deeply inward on each side of the aorta, feeling for pulsation can used one hand with thumb and fingers on either side of the aorta
185
the nurse percuss the abdomen to obtain which information
presence of masses presence of ascites gastric distention size of organ
186
which abdominal structures are assessed through percussion
splee liver kidneys
187
which type of palpation is necessary to delineate abdominal organs and detect masses?
deep palpation
188
alvarado score
eval migration of pain, anorexia, nausea/vomiting, tenderness in lower quad, rebound pain, temp. leukocytosis, and left shift used to diagnosis appendicitis in both children and adult
189
pediatric sppendicitis score
eval pain with cough or hopping or rebound tenderness with the percussion of the RLQ
190
Ohmann score
use patient age, history, and physical exam and laboratory finding to identify risk of appendicitis
191
rebound tenderness (McBurney Sign)
press gently on abdomen, then rapidly withdraw hands and fingers and note if pain increase when hand is released
192
iliopsoas muscle test
patient raise right leg from hip while nurse press downward against it. then extend right leg by drawing backward with the patient lying on their left side indicate irritation of the iliopsoas muscle and appendicitis
193
Obturator muscle test
patient lying supine, patient flex right leg at hip to 90 degree and rotate leg medially, then laterally. Pain in right hypogastric region indicate irritation of obturator muscle, a rupture appendix or pelvic mass
194
Ballotement
nurse place extended fingers, hand, and forearm at 90n degree angle to the abdomen and pushes toward the organ or mass with fingertips. if mass freely moveable, it will float upward and touch fingertip as fluid and other structure are displaced assess a mass
195
how should the nurse assess for ascites
look for fluid wave identifying shifting dullness on percussion
196
which test should be performed if the nruse suspects a rupture appendix
obturator muscle test
197
ausculatio of bowel sound
5-35 irregular clicks and gurgles per minutes Borborygmi (increased sounds) may be present with hunger
198
ausculate vascular assessment
done over arota, renal, artery, iliac artery, and femoral artery using the bell of stethoscope Liver and spleen silent no bruits, venous hum, friction rub
199
percussion of abdomen
1. tympany as the predominant sound 2. dullness over organs and solid masses 3. dullness over suprapubic region from distended bladder 4. lower border of liver beginning as costal margin 5. upper border of the liver beginning at the 5th or 6th intercostal space 6. liver span abouit 6-12 cm 7. spleen small area of dullness from 6th - 10th rib with typmpany before and after deep breath 8. stomach: tympany of gastric bubble
200
which finding regarding movement would be considered normal on inspection of the abdomen
smooth movement even movement
201
pulsation
an abnormal finding and indicate increased pulse pressure or an aortic aneurysm
202
limited movement
abnormal finding and may indicate peritonitis
203
rippling movement
may be seen in thin individuals but often abnormal, suggesting intestinal obstruction
204
auscultation of the abdomen, which findings related to bowel sounds would be considered normal
gurgles clicks irregular
205
high pitch tinkling bowel sound
irregular finding and may suggest an early obstruction
206
absense of bowel sound
irregular finding and is a medical emergency
207
verticle span of th eliver is expected to be 6 to ___ cm
12
208
on palpation of a patient's umbilical ring, the nurse notes slight granulation but no bulges or nodules. additionally, the umbilical ring is round and slightly inverted. which finding are considered normal
lack of bulges lack of nodules round umbilical ring inverted umbilicle ring
209
which finding would be considered normal on inspection of the abdomen of an infant
dome shape
210
on auscultatio of infant's abdomen, peristalsis should be heardhow often
10-30 seconds
211
how are the palpation findings of older adults different from those of younger patients?
softer due to decrease muscle tone and mass
212
which normal finding in older adults predispose this patient population to intestinal disorders
decrease intestinal motility
213
peritoneum
abdominal lining serous membrane forming a protective cover
214
parietal peritoneum
line abdominal walls
215
viscerla peritoneum
covers organsp
216
peritoneal cavity
space between parietal and visceral layer contains serous fluid that reduces friction between organs and membranes
217
pepsin
break down protein to peptone and amino acid
218
gastric lipase
emulsify fats triglycerides to fatty acis or glycerol
219
pH of stomach
2-4
220
what system control peristalsis
Autonomic nervous system
221
nephrons
functional units of the kidneys remove waste products from blood regulatio of fluids and electrolyte balance
222
protenuria
protein in urine suspected injury to glomerulus
223
hematuria
blood in urine
224
glomerular filtrate
excreted as urine 99% reabsorbed into the plasma by proximal convuluted tubules, the loope of Henle, and distal convuluted tubles. 1% excreted as urine
225
normal range of urine production
1-2 L/day
226
what factors influence production of urine
fluid intake and temperature
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Erythropoietin
produced by kidneys stimulate red blood cell production and maturation in bone marrow
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renin-angiotensin system
renin released from juxtaglomerular as enzyme to convert antiotensinogen (synthesized by liver) into angiotensin I. and Angiotensin II (in lungs) causes vasoconstriction and stimulate aldosterone release from adrenal cortex. aldosterone cause retention of water which increase blood volume and blood pressure
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prostaglandin and prostacyclin
maintain renal blood flow through vasodilation increase arterial blood pressure and renal blood flow
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kidney impairment
problems with anemia, hypertension, and electrolyte imblance
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ureters
attached to each kidneys and carry urine from kidney pelvis to bladder urine drainage from ureter to bladder is sterile
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contraction of bladder
compress lower part of ureters to prevent backflow into ureters
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urinary reflux
backflow of urine into the ureters
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hydroureter/hydronephrosis
distention of pelvis of kidney due to backflow cause permanent damage to sensitive kidney structures and functions
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bladder
lies in pelvic cavity behind symphysis pubis has two part: trigone--fixed base detrusor-distensible body
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pressure in bladder
remains low while filling, preventing backflow
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urethra
passes through thick layer of skeletal muscle called pelvic floor muscles
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pelvic floor muscle
stabilize the urethra and contribute to urinary continence
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external urinary sphincter
made up of striated muscles contribute to voluntary control over the flow of urine
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female urethra
3-4 cm (1-1 1/2 inches) long
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male urethra
18-20 cm (7-8 inches) long
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urination
process of bladder emptying also known as micturation and voiding
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bladder fills
400-600 mL
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urinary retention
inability to empty the bladder partially or completely
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acute or rapid onset urinary retention
stretches bladder causing feeling of pressure, discomfort/pain, tenderness over symphysis pubis, restlessness, and sometimes diaphoresis no urine output over several hours frequency, urgency, incontinence, sensation of incomplete emptying
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postvoid residual (PVR)
amount of urine left in the bladder after voiding and is measured with ultrasonography or straight cath
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overflow incotinence
incontinence caused by urinary retension pressure in bladder exceeds the ability of the sphincter to prevent passage of urine, and the patient will dribble urine
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transient incontinence
cause by medical condition and in many cases are treatable and reversible
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Functional incontinence
loss of continence because of cause outside urinary tract due to altered mobility, cognitive impairment, environmental barriers
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stress urinary incotinence
involuntary leakage of small volume of urine associated with increased intraabdominal pressure related to either urethral hypermobility or an incompetent urinary sphincter, weak pelvic floor muscles, trauma after childbirthu
251
urge or urgency incontinence
passage of urine often associated with strong sense of urgency related to overactive bladder cuased by neurological problems, bladder inflammation, or bladder outet obstruction
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reflux urinary incontinence
loss of urine occuring at somewhat predictable intervanls when patient reaches specific bladder volume related to spinal cord damage between c1 and s2
253
bacteriuria
bacteria in urine can be asymptomatic bacteriuria
254
pyelonephritis
upper UTI
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bacteremia
life-threatening bloodstream infection
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dysuria
burning or pain with urination
257
cysitis
irritation of the bladder
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cauti
catheter associated urinary tract infection most common hospital acquired infection
259
urinary incontinence
complaint of involuntary loss of urine
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Types of UI
urgency stressed overflow
261
cystectomy
bladder removal
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urinary diversion
procedure that diverts urine to the outside of the body through an opening in the stomach wall called a stoma
263
oxybutynin
antimuscarinic agent treatment of urinary urgency cause dry mouth, constipaton, and blurred vision cause congnitive impairment
264
nitrofurantoin
antibiotic used to treat UTI
265
Nethanechol
used to treat urinary retention cause nausea, vomiting, diarrhea, and increase salivation
266
phenazopyridine
analgesiac patient with painful urination associated with uti turn urine orange
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a patient who undergone urological surgery is prescribed cath. which diameter of cath does the nurse anticipate to used for this patient
greater than 16 Fr
268
patient has a full bladder, and is having difficulty voiding. which instruction would the nurse provide patient?
use crede method put pressure on the suprapubic area with each attempted void. relax sphincter
269
post op patient has not voided for 6 hours which method would benefit in assisting patient to void
standing at bedside man void more easier in standing position
270
squatting position when voiding does what in female
promotes compete bladder emptying
271
overflow UI
characterized by nocturia, frequency and distended bladder on palpation
272
instruction regarding bladder training would be included in the teaching plan for the family of a patient who is incontinent because of a stroke
offer patient the commode or urinal every 2 hours
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positive keytones in urine
keytone is byproduct when body use fat for energy production starvation dehydration uncontrolled diabetes mellitus
274
UTI infection
symptoms dysuria, urgency, frequency, and nocturia
275
normal patient should consume how much fluid
2300 mL
276
ventilation
movement of air from the atmosphere thorugh the upper and lower airway to the alveoli
277
respiration
process where gas exchange occurs at the alveolar-capillary memnrane
278
perfusion
involves blood flow at the alveolar-capillary bed
279
diffusion
movement of molecules from higher to lower concentration, takes place when oxygen passes into the capillary bed to be circulated and CO2 elaves the capillary bed and diffuses into the alveoli for ventilation excretion.
280
upper respiratory infection
common cold acute rhinitis sinusitis acute pharyngitis
281
most preventative type of URI
common cold adult have average 2-4 colds per year children have 4-12 colds per year
282
Acute rhinitis
inflammation of the mucous membranes of the nose, usually accompanies the common cold
283
allergic rhinitis
known as hay fever caused by pollen or a foreign substance such as animal dande
284
drug used to manage cold symptoms
antihistamine (H1 blockers), decongestant (sympathomimetic amines), antitussive, and expectorants
285
rehinorrhea
watery nasal discharge
286
symptoms of common cold
rhinorrhea nasal confestoin cough increase mucosal secretions
287
antihistamine
H1 blockers or H1antagonists compete with histamine for receptor sites and prevent a histamine response
288
diphenhydramine pharmacokinetic
first generation antihistamine oral, IM, or IV absorbed well through GI, minimal with topical 98% protein bound half life of 2-8 hours metabolizzed through liver and excreted in urine
289
diphenhydramine side effect
drowsiness, dizziness headache, weakness, insomnia, fatigue, urinary retention, blurred vision, dry mouth, dermititis, rash, paresthesia, abdominal pain, restlessness, confusion, diarrhea, constipation
290
therapeutic effect/ use of diphenhydramine
treat insomnia and allergic reaction including rhinitis, the common cold, cough, sneezing, pruritus, and urticaria and to prevent motion sickness mechanism of action: compete with histamine for binding at h1 receptor sites and antagonize histamine effects
291
adverse reaction of diphenhydramine
seizuress life threatening thromnocytopenia
292
second generation antihistamine
cetirizine fexofenadine azelastine desloratadine loratadine