Week 8 Flashcards
Total Body water
accounts for 60% of a healthy adult body weight
influenced by age, gender, and overall health
regulate body temp
lube joints
shock absorption for internal organ
transport nutrient and waste
metabolic reactions inside of cells
TBW for ICF
67%
TBW ECF
33%
types of fluid
intracellular (inside cell)
interstitial (between the cell in the tissue)
extracellular (outside cell)
intravascular (inside the vessel)
transcellular (outside the vessel)
composition of fluid
water is responsible for the transport of molecules throughout the body
water is the body’s major solvent
solutes
particles that completely or partially dissolve in a solvent and can be classified as either crystalloid or colloid
crystalloid sollute
small and completely dissolved in solvent
easily passed through capillary veins
intravenous fluids often referred to as crystalloid solution
electrolyte
a type of crystalloid
charged atom molecules measured in milliequivalent per liter of water (mEq/L)
have a positive (cation) and negative
(anion) charge
examples are sodium, potassium, calcium, magnesium, and chloride
nonelectrolytes
molecules without a charge
glucose, amino acid, gases (oxygen and carbon dioxide)
colloid solute
particles that are too large and do not fully dissolved in a solvent
does not easily pass through walls and cell membrane
proteins and starches (albumin and clotting protein)
blood and blood product
difference of TBW
males have 60%
females have 60%
elderly and obese have 45%
osmosis
the passive transport of water between fluid compartments
movement of water in and out of the cells
from low concentration to high concentration
allow water to move across but not solutes
osmotic pressure
solution exerts a force on either side of the selectively permeable membrane
pressure increases as concentration between compartments becomes greater
inward pulling force of solutes that move the water across a semipermeable membrane to an area of higher solute concentration
osmotic pressure in intravascular controlled by concentration plasma protein (albumin)
osmolality
concentration of solute in body fluids
measured in milliosmoles/kilogram (mOsm/kg)
equalizes rapidly
dehydration increase concentration of solute extracellularly cause rapid movement of water from the cells
Filtration
movement of water and solute together between vascular and interstitial compartments
move from high pressure to low pressure
hydrostatic pressure
exerted by fluid in the blood vessel
controlled by arterial blood pressure (heart rate, strength of cardiac contraction, systemic vascular resistance) and blood flow in the capillary bed
capillary hydrostatic pressure is higher on the arterial side than on the venous side
osmotic pressure is lower in the arterial side than venous side
the net effect contribute to constant shifting of water and solute
blood cells and plasma protein does not get filtrated in kidney
oncotic pressure
a type of osmotic pressure (colloid osmotic pressure)
the pressure in intravascular space is controlled by concentration of plasma protein (albumin)
plasma proteins attract water molecules to them and are responsible for water in the intravascular space.
hydrostatic pressure
the outward-pushing force of water against the walls
as blood flows through the capillaries, it pushes (exerts pressure) against the vessel walls
hydrostatic pressure must be greater than oncotic pressure for filtration across capillaries to occur
Edema in patients
means imbalance where hydrostatic pressure is greater than intravascular osmotic pressure leading to a fluid accumulation in the tissue
fluid intake
comes from consumption of fluids or food
some generated from metabolic processes (digestion of carbs)
influenced by habit and social and cultural factors
thirst sensation decrease as a normal part of aging
fluid output
done through kidney (excreted as urine)
loss through diaphoresis, insensible perspiration, and respiration
small amount of loss through feces
aldosterone and natriuretic
regulate extracellular fluid volume
antidiuretic hormone (ADH)
regulate osmolality
high serum osmolality causes the secretion of ADH
cause reabsorption of water in the kidney leading to concentrated urine and less concentration of plasma
low osmolality will prevent secretion of ADH.
This cause a decrease in water reabsorption in the kidney, leading to a dilute urine and concentrated plasma
fluid volume and composition maintain homeostasis by which mechanism
renal system
renin-angiotensin system
secretion of ADH
thirst mechanism