Week 6 Revision Flashcards

1
Q

Define cancer

A

Abnormal cells growing uncontrollably, which can then form a tumor. This can grow and spread to other tissue within the body

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2
Q

List two ways to reduce the risk of cancer

A
  • Maintain a healthy weight

- Be physically active

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3
Q

Cancer can be caused by genetic damage, list 2 different causes of genetic damage

A

1) Cigarette smoking

2) Lack of fruit and veg

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4
Q

What are two different catogories of lung cancer?

A

1) Small cell lung cancer

2) Non small cell lung cancer

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5
Q

What is proto-oncogenes?

A

Promotes growth within the body. Sometimes they can get stuck to be constantly working, this will cause the cell to replicate when the body does not need it to - this is when cancer starts.

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6
Q

What is tumour suppressor genes?

A

When a proto-oncegenes is stuck on, the tumour supresssor gene stops the replicating cell. This stop the cancer from mutiplying and spreading

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7
Q

What is apoptosis?

A

When the tumour suppresor genes tell a replicating cell to kill itself so it does not cause harm to the other cells. The cell will slowly start to give out the good parts, such as nutrients, to other cells, resulting in the cell getting smaller, and then eventually it is fully gone

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8
Q

How does HPV affect tumour suppressor genes?

A

It causes these genes to not work, therefore the cancerous tumour does not die, so it will start to replicate and spread

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9
Q

Cancer cells have high energy requirments, and need a lot of nutrients. What do the cells do to ensure they get these requirments?

A

The cancer cells creates new blood vessels to ensure they get teh nutrients.

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10
Q

How does a cancer cell spread? What is this called?

A

A caner cell wants to spread around the body, therefore some of the cell will break off and travel around the body, and attach itself to a new tissue - this is called secondary cancer

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11
Q

What are the two different types of treatment for cancer?

A

1) Surgery > to remove the tumour

2) Radiotherapy > to kill the cancer cells

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12
Q

Explain how anti-cancer medication harms healthy cells and cancer cells

A

The drug will be administered, which will then kill any cell which is replicating (not only cancer cells) > healthy cells can replicate faster than cancer cells, therefore they recover > another dose of medication is given, but the cancer cells have no had enough time to recover > this process repeats until the cancer cells die > a healthy cell can only replicate so many times before it dies, therefore there is still going to be death of a healthy cells, which then makes the patient ill

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13
Q

What is a new therapy used to treat cancer? Explain

A

Biological therapy is medication to boost the immune system, OR it will make the cancer cells visible to the immune system, allowing the immune system to see it and fight it. The drug might bind to the cancer cells receptors which then sends off red flags > THIS WILL NOT KILL ALL CELLS ONLY CANCER CELLS, therefore you wont have your healthy cells dying, but you’ll still get sick because your immune system has been activated

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14
Q

What two things does a patient of cancer die from?

A

Secondary cancer

Complications of cancer or its treatment

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15
Q

When does cachexia affect a patient?

A

This disorder tends to affect people who are the final stages of serious diseases such as HIV or AIDS, COPD, kidney disease and cognitive heart failure.

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16
Q

What is precachexia?

A

A loss of up to 5% of the body weight while having a known illness or disease

17
Q

What are two signs and symptoms of precachexia?

A
  • Appitete loss

- Inflammation

18
Q

How much % of body weight is lost to dignose cachexia?

A

A loss more than 5%

19
Q

What are two signs and symptoms of cachexia?

A
  • Decreased appetite

- Fatigue

20
Q

What is refectory cachexia?

A

Specific to patients who have cancer; it is weight loss, muscle loss, loss of function and failure to respond to cancer treatment.

21
Q

Explain how body protein is broken down during cachexia

A

Normally, the body will use glycogen from the liver, or adipose tissue when someone has not eaten for a while; in cachexia, the body is treated as it is starving, and goes straight to breaking down body protein.

22
Q

What is the meaning of ‘tumour’?

A

Swelling in the body, due to an abnormal growth of tissue

23
Q

What is the meaning of ‘neoplasm’?

A

New growth - usually associated with cancer

24
Q

What is the meaning of ‘benign’?

A

(tumour) is less likely to spread to other parts of the body, however it can still cause problems as it swells and pushs against parts of the body

25
Q

What are three characteristics of cancer cells?

A
  • they can continue to replicate more than a healthy cell
  • they replicate slower than a healthy cells
  • reistant to apopiosis
26
Q

What are two life-style choices that an individual could adopt in an attempt to reduce their risk of devloping cancer?

A
  • eating a healthy, balanced diet

- stop smoking

27
Q

Name two classes of drugs used to treat cancer

A

Cycle specific

Phase specific

28
Q

What are the biggest types of cancer?

A

Lung
Breast
Prostate
bowel