Week 8

Question 1

it is the chemistry of space

Answer 1

stereochemistry

Question 2

Stereochemistry is a branch of chemistry that involves the study of the different _________ of atoms in molecules

Answer 2

spatial arrangement

Question 3

it refers to the 3-dimensional arrangement of atoms

Answer 3

stereochemistry

Question 4

the same order but different intrinsic shape

Answer 4

stereoisomer

Question 5

(True or False)
Chiral is superimposable (identical) on its mirror image

Answer 5

False
(achiral)

Question 6

(True or False)
Chiral is not super imposable (not identical on its mirror image

Answer 6

True

Question 7

(True or False)
The most common source of molecular chirality is the presence of carbon atom bearing 3 different groups

Answer 7

False
(4 different groups)

Question 8

In 1996, the IUPAC recommended that a tetrahedral carbon bearing 4 different groups be called

Answer 8

chirality center

Question 9

Other names for chirality center

Answer 9

chiral center, stereocenter, stereogenic center and asymmetric center

Question 10

(True or False)
CH2 and CH3 can be tetrahedral stereogenic centers

Answer 10

False
(more than one H bonded to C)

Question 11

(True or False)
Any sp or sp2 hybridized C can be tetrahedral stereogenic centers

Answer 11

False
(less than four groups around C)

Question 12

is bronchidilator that widen airways so it is used to treat asthma

Answer 12

Albuterol

Question 13

is an antibiotic used extensively in developing countries because of its low cost

Answer 13

chloramphenicol

Question 14

same chemical formula but different structures

Answer 14

isomers

Question 15

isomers that have different connectivity

Answer 15

constitutional isomers

Question 16

isomers that have the same connectivity but different spatial arrangement (configuration)

Answer 16

stereoisomers

Question 17

mirror-image isomers

Answer 17

enantiomers

Question 18

non-mirror image isomers

Answer 18

diastereomers

Question 19

2 types of diastereomers

Answer 19

configurational and cis-trans

Question 20

(True or false)
Constitutional isomer can have the same IUPAC names

Answer 20

False
(different IUPAC name)

Question 21

(True or false)
Constitutional isomer have different physical and chemical properties

Answer 21

True

Question 22

Constitutional isomer have similar or different functional groups

Answer 22

True

Question 23

(True or false)
Constitutional isomer have different formula and connectivity

Answer 23

False
(same molecular formula)

Question 24

are compounds whose atoms are connectivity in the same order but with a different spatial arrangement

Answer 24

Stereoisomers

Question 25

these are nonsuperimposable mirror-image (chiral) stereoisomer

Answer 25

enantiomers

Question 26

these are nonsuperimposable non-minor image stereoisomer

Answer 26

diastereomers

Question 27

Test for chirality

Answer 27

(1) Presence of a single chirality center (2) plane of symmetry

Question 28

(True or False) A molecule will be chiral if it possesses a plane of symmetry

Answer 28

False (will not be chiral)

Question 29

A plane symmetry also called

Answer 29

mirror plane

Question 30

Defined as an imaginary plane that bisects a molecules in a way that the two halves of the molecule are mirror images of each other

Answer 30

plane symmetry

Question 31

(True or False) All molecules with a plane of symmetry in their most symmetrical conformation are achiral

Answer 31

True

Question 32

anti inflammatory agent

Answer 32

(S)-naproxen

Question 33

liver toxin

Answer 33

(R)- naproxen

Question 34

(True or False) When naming a chiral compound, the configuration of the chirality center is indicated at the beginning of the name, italicized, and surrounded by parentheses

Answer 34

True

Question 35

(True or False) When multiple chirality centers are present, each configuration must be preceded by a locant (a number) to indicate its location on the parent chain

Answer 35

true

Question 36

Pure enantiomers have ________melting and boiling points

Answer 36

identical

Question 37

(True or False) Enantiomers show the same behavior only when they interact with other chiral substances, including their own enantiomer

Answer 37

false (different)

Question 38

When a beam of plane-polarized light passes through an enantiomer, the plane of polarization _______.

Answer 38

rotates

Question 39

(True or False) Separate enantiomers rotate the plane of plane-polarized light equal amounts but in same directions

Answer 39

false (opposite)

Question 40

is an electromagnetic phenomenon

Answer 40

light

Question 41

A beam of light consists of two mutually perpendicular oscillating fields:

Answer 41

oscillating electric field oscillating magnetic field

Question 42

The device that is used for measuring the effect of optically active compounds on plane-polarized light is a

Answer 42

polarimeter

Question 43

principal working parts of a polarimeter are

Answer 43

(1) light source (2) polarizer (3) cell (4) analyzer (5) scale

Question 44

a light source is usually a

Answer 44

sodium lamp

Question 45

for holding the optically active substance (or solution) in the light beam

Answer 45

cell

Question 46

for measuring the angle (in degrees) that the plane of polarized light has been rotated

Answer 46

scale

Question 47

(Direction of rotation) left or counterclockwise

Answer 47

levorotatory(-)

Question 48

(Direction of rotation) right or clockwise

Answer 48

dextrorotatory(+)

Question 49

He is the father of organic stereochemistry

Answer 49

Louis Pasteur

Question 50

In 1848, Pasteur published a study on the recrystallization of various salts of_________, which are found naturally in wine (aka “________”).

Answer 50

tartaric acid, or “tartrates” wine diamonds

Question 51

An equal mixture of two enantiomers is called

Answer 51

racemic mixture or racemate