Week 9 - GI emergencies and nutrition Flashcards
(13 cards)
What are the 4 liver enzymes?
AST - necrosis
ALKP - obstructions. P = plug
ALT - acute injury
GGT - along with ALKP
Name one major protein that is synthesized in the liver and plays a primary role in onctoic pressure?
Albumin
Name 3 drugs that can cause liver toxicity
Xylitol
Acetaminophen
Carprofen
Aspirin
What are the liver’s primary role
Energy - glucose and carb production
Stores and metabolizes proteins - albumin, prothrombin, factor X, fibrinogen
Clotting factors
Vitamin K - clotting cascade, A, D, E. B12
Iron, copper
Enzymes - ALT, AST, GGT, ALKP
Thermoregulation
Deamination process
Regulate glucose
Coagulation
What is the largest gland in the body?
Liver - secretes bile
What are the main functioning cells of the liver
Hepatocytes
About___% of blood into the liver comes from stomach and small intestines
80%
These cells help remove bacteria in the blood which leak in from stomach and intestinal walls
Kupffer cells
One important trace element is excreted in bile
Copper
What lab work may appear with liver failure?
Hyperbilirubinemia
Hypoglycemia
Increase in NH3
Prolonged coags -PT and aPTT
Low albumin
High ALT, ALKP, GGT, AST
High values of this can indicate liver shunt or hepatitis
Ammonia
Trace amounts of bilirubin can be normal in ____ (concentrated) and always abnormal in _____
Dogs
Cats
How can anemia affect the liver?
Hypoxia leads to decreased production of Vitamin B12, which produces hemoglobin = anemia