Flashcards in Workbook - Skin Deck (71)
How many layers is skin composed of?
What is the outer layer of skin called?
What is the underlying layer of connective tissue in skin called?
What is deep to the dermis?
-layer of loose connective tissue with variable amounts of fat
What are the layers of skin?
What determines whether skin is defined as thin or thick?
The thickness of the epidermis.
-particularly the outer layer of epidermis
What is another difference between thick and thin skin (apart from the thickness of the epidermis)?
Thin skin has hair follicles, thick skin is glabrous (non-hairy).
Where is thick skin generally located in humans?
Areas with lots of abrasion.
-fingertips, palms, soles
What type of epithelium is the epidermis made up of?
Keratinised stratified squamous.
What are the main layers of thick skin? (5)
DEEP TO SUPERFICIAL:
What is stratum basale responsible for?
Regeneration (repeated mitotic divisions).
What is stratum spinosum composed of?
Keratinocytes connected by desmosomes.
What is stratum granulosum composed of?
Loose nuclei and cytoplasms >> masses of keratin.
What is stratum lucidum like, and where is it found?
Thin and transparent.
-in the palms and soles
What is stratum corneum composed of?
Sheets of keratin.
-contains most barrier functions
Which layers of thick skin are most prominent?
Which layer of thick skin is absent in thin skin?
What are the 3 types of non-epithelial cells present in the epidermis?
What are melanocytes?
The pigment cells of the skin.
Which non-epithelial cells in the epidermis play a role in immunology?
Which non-epithelial cells in the epidermis act as mechanoreceptors?
What are the main types of skin cancer? (3)
-Basal cell carcinoma
-Squamous cell carcinoma
How do the different types of skin cancer vary?
Each derived from different layers of the epidermis.
What layer of the epidermis is basal cell carcinoma derived from?
What layers of the epidermis is squamous cell carcinoma derived from?
Upper layers (keratinocytes/granular).
-stratum spinosum and stratum granulosum
What layer of the epidermis is malignant melanoma derived from?
Which type of skin cancer is the least common and most dangerous?
What are warts?
Small benign growths caused by viral infection (HPV) of the skin/mucous membrane.
>> increase keratin production in the epidermis
What happens during development to a number of epidermis structures?
They grow downwards to invade the underlying dermis and hypodermis.