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NPTE Integumentary System > Wound Healing > Flashcards

Flashcards in Wound Healing Deck (41)
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1

What is the body's largest organ?

Integumentary system (Skin)

2

What layers make up the integumentary system?

Epidermis
Dermis
Subcutaneous fatty tissue

3

What is the most superficial layer of skin?

Epidermis

4

What layer of skin is considered the true skin?

Dermis

5

Distinguish which layers of skin are vascular versus avascular.

Epidermis = avascular
Dermis = vascular

6

What are the five key functions of the integumentary system?

Protection
Sensation
Thermoregulation
Excretion of sweat
Vitamin D synthesis

7

What are the 3 phases of wound healing?

Phase 1: Inflammatory
Phase 2: Proliferative
Phase 3: Maturation

8

How long does the inflammatory phase last?

1-10 days

9

How long does the proliferative phase last?

3-21 days

10

How long does the maturation phase last?

7 days to 2 years

11

What is the immune system's initial response to a wound?

Inflammation

12

How does the body rapidly establish homeostasis in the presence of a wound? What phase does this occur in?

Through platelet activation and the clotting cascade
Occurs in the INFLAMMATORY phase

13

What 4 things occur in the inflammatory phase of wound healing?

1. Re-establish homeostasis via platelet and clotting cascade activation
2. Removal of debris and necrosis
3. Bacteria killed by mast cells, neutrophils and leukocytes
4. Re-epithelization

14

What is the main goal of the inflammatory phase of healing?

Establish a clean wound bed which signals tissue restoration and the start of permanent wound healing

15

When does re-epithelization typically begin?

Within 24 hours

16

What signals the beginning of the proliferation phase?

Formation of new tissue

17

What is restored during the proliferative phase?

Skin integrity

18

What 3 things occur in the proliferative phase of wound healing?

1. Capillary buds and granulation tissue fill the wound bed
2. Collagen matrix is formed
3. Epithelization and wound contraction

19

What 2 processes give rise to wound closure?

Epithelization
Wound contraction

20

When is the maturation phase initiated?

When granulation tissue and epithelial differentiation appear in the wound bed

21

What 2 things occur in the maturation phase of wound healing?

1. Fiber reorganization and contraction shrink the scar
2. Collagen lysis and synthesis strengthen the scar tissue

22

What 2 processes shrink the scar tissue?

Fiber reorganization and contraction

23

What 2 processes strengthen the scar tissue?

Collagen lysis and synthesis

24

What are characteristics of an immature scar?

Red
Raised
Rigid

25

What are characteristics of a mature scar?

Pale
Flat
Pliable

26

Newly repaired tissues have approximately ____ % of pre-injury tensile integrity and should be protected to prevent re-injury.

15%

27

Over time tensile integrity may increase to up to ___ % of pre-injury strength.

80%

28

What condition can significantly impact the maturation phase of healing?

Hypertrophic scarring

29

What type of wounds are typically treated with healing by primary intention?

Acute wounds with minimal tissue loss

30

What is healing by primary intention?

Closing the edge of a wound with sutures, staples or adhesives to facilitate re-epithelization