ZOONOTIC DISEASE Flashcards

1
Q

What is the causative agent of RMSF

A

Rickettsia Rickettsii

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2
Q

RMSF the caustivie organism?

A

Tick

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3
Q

Presentation of RMSF

A

Abrupt headache
photophobia
vomiting
centripetal inward spreading macular rash

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4
Q

Tx of RMSF

A

Doxycycline

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5
Q

The causative agent of Lyme Disease?

A

Borrelia Burgdorferi— It is a SPIROCHETE

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6
Q

Stage 1 presentation of lymes disease?

A

Erythema migrans,

Viral like syndrome

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7
Q

Stage 2 presentation of lymes disease?

A

Arthrittis

myocarditis

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8
Q

Stage 3 presentation of lymes disease?

A

Chronic Arthritis

Chronic Encephalopathy

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9
Q

Treatment of lymes disease?

A

Doxycycline

Children and pregnant women: Amoxicillin

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10
Q

What is pathognomonic for lyme disease?

A

Bilateral facial nerve palsy

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11
Q

What is the most common type of tularemia?

A

Ulceroglandular disease

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12
Q

How does ulceroglandular disease of tularemia present?

A

Ulcerated skin
regional lymphadenopathy
fever

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13
Q

Glandular Tularemai? #2 presentation?

A

Regional lymphadenopathy without skin lesion found in ulceroglandular.

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14
Q

What are the primary treatments for tularemia?

A

Streptomycin

Gentamicin

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15
Q

What are the tick borne illnesses?

A

Rocky Mountain Spotted Fever
Lyme disease
Tularemia
Relapsing fever

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16
Q

Mosquito-Borne Illnesses

A

Dengue fever
Zika virus
Ebola Hemorrhagic Fever
Mosquito-Borne Encephalitis

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17
Q

Rat- and Flea-Borne

A

Hantavirus Pulmonary Syndrome

Plague

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18
Q

What is the presentation of relapsing fever?

A

Repeating 3-10 days relapses of fever (VERY HIGH) and rash.

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19
Q

What is the treatment for Relapsing fever?

A

Doxycycline

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20
Q

What is the geographic distribution of dengue fever?

A

tropical and subtropical regions.

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21
Q

Presentaiton of dengue fever?

A

Flue like symptoms with a rash progressing to Dengu hemorrhagic fever

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22
Q

what is a saddleback pattern with dengue fever?

A

but subsequent infections are typically more severe `

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23
Q

Define presentation of Dengu hemorrhagic fever

A

Characterized by GI hemorrhage and plasma leakage into chest and peritoneal cavities
Occurs after fever breaks

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24
Q

What is the turniquite test for dangue fever?

A

Easy bruising, epistaxis, mucosal bleeding

with the placement of the tourniquet

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25
Q

What type of rash presents with recovery phase of dengue hemorrhagic fever?

A

White islands in a sea of red.

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26
Q

What is the causitive bug of zika virus?

A

misquito

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27
Q

What are the clinical manifestions of Zika virus?

A

Microcpharly of feal brain.

Zika can be detected in semen up to 3-6 months after initial infection

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28
Q

What is the diagnostics for zika virus?

A

Serum and urin zika RNA nucleic acid testing

29
Q

Which mosquito-born disease has a vaccine for it?

A

Japenese Encephalitis

30
Q

What is the most severe mosquito bone illness in the US ?

A

Eastern Equine Encephalitis

31
Q

What is the transmission resevieor for ebola?

A

Bush meat—– bats, gorilla, chimpanzees

32
Q

Where is the MC geographic area for hantavirus

A

4 corners area.

33
Q

Wht is the treatment for ebola?

A

supportive

34
Q

What is the presentation of west-nile virus?

A

Most cases are asymptomatic

35
Q

What is the geographic distribution of western equine encephalitis?

A

North and South america

36
Q

Presentation of western equine encephalitis?

A

Most cases are asymptomatic

Mortality in neuroinvasive diasese- mostly in children

37
Q

What is the geographical distribution of eastern equine encephalitis?

A

Atlantic and gulf coast states

38
Q

What is the transmission of Hantavirus?

A

aerosilized virus form infected rodent excreta, saliva, and urine.

39
Q

What is the treatment for the plague?

A

Streptomycin

Gentamicin

40
Q

What is the MC form of the plague?

A

Bubonic Plague

41
Q

What is the geographic distribution of the plague?

A

SW United States, SA, Africa, Asia

42
Q

Reservoir for rabies?

A

Raccoons, Bats, skunks, dogs

43
Q

Presentation of rabies?

A

hydrophobia, agitation, spasms

44
Q

What is the treatment of rabies?

A

Clean the wound, Rabies Immunoglobulin at the wound site and vaccination

45
Q

What are the two types of rabies presentation?

A

Furious Rabies: Hyperactivity, disorientation, agitation

Paralytic Rabies: Less common, Ascending Paralysis.

46
Q

What is the Dx of Rabies?

A

Negri Bodies histologically.

47
Q

What is the most common transmission of rabies?

A

Developing countries: Canine to human

Developed Countreis: wild carnivores to domesticated animal.

48
Q

Transmission of cat scratch disease?

A

Gram- Negative zoonosis to cats via flea.

49
Q

Diagnosis of Cat- Scratch Disease?

A

IgM and IgG antibodies

50
Q

Treatment of Cat- Scratch disease?

A

Azithromycin

51
Q

What is also cuased by the bite of a CAT

A

Pasteurella Multocida

52
Q

What is pasteurella mulocida?

A

Encapsulated Gram- Negative Rod

53
Q

How to treat Pasteurella Multocida?

A

Do not stich up becasue it is an anerobe.

Amoxicillin-clavulanate

54
Q

What is the resevior of chagas disease?

A

opossum, raccoons, armadillos, rodents

55
Q

What is the causative agent of chagas disease?

A

Trypanosoma cruzi

56
Q

What is the geographic distribution of Chagas disease?

A

mexico , Central and South America. Southern US

COAST RICA

57
Q

What is a chagoma?

A

localized erythema and edema (where parasite entered the skin)

58
Q

What is Romana Sign?

A

painless palpebral edema and conjunctivitis 1-2 weeks after parasite entry through conjunctiva of the infected eye

Chagas Disease

59
Q

What are the chronic manifestations of Chagas disease?

A

Dilated cardiomyopathy……….

60
Q

What is the treatment of Chagas Disease?

A

Benznidazole

61
Q

What is the causative agent of Psittacosis?

A

Chlamydia Psittaci

62
Q

What is the reservior of Psittacosis?

A

Birds

63
Q

What is the transmission of psittacosis?

A

Feces of certian birds

64
Q

MC presentation of Psittacosis?

A

Atypical Pneumonia + Severe Headache symptoms

65
Q

What is the treatment of Psittacosis?

A

Doxycycline or Tetracycline

66
Q

What is the reservoir of brucellosis?

A

Sheep, swine, cattle, dogs

67
Q

What do half of all the bison in yellowtone have?

A

Brucellosis

68
Q

How is brucellosis transmitted?

A

exposure to infectious fluids from animals or food products. Raw milk, unpasteurized cheese.

69
Q

What is the treatment of brucellosis?

A

Doxycycline + streptomycin