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Decks in this class (36)
Lecture 1 - B cells - Immune Deficiencies 1
What are rsss in which cells are ...,
What are the various enzymes that...,
Describe the function of rag1 rag2
70
cards
Lecture 11 - CF - Multisystem disorder
What are some other systems that ...,
What is the life expectancy for i...,
What is the gold standard test fo...
41
cards
Lecture 2 - B cells - Immune Deficiencies 2
What is the phenotype of mice lac...,
What is a combined immune deficiency,
What is the name for humoral defi...
62
cards
Lecture 3 - HIV & Vaccines
What are the three main types of ...,
Describe the changes in viral loa...,
What is the desired effect of an ...
29
cards
Lecture 4 - B cells and Cancer
What are the hallmarks of cancer,
What features of b cells are a ca...,
What are the categories of malign...
67
cards
Lecture 5 - mAbs
Which cell type produces ig and i...,
What is a monoclonal antibody,
What factors give mabs great ther...
71
cards
Lecture 7 - CF: Personal Perspectives
People from which backgrounds are...,
What is the aetiology of cf,
What is the cure for cf
20
cards
Lecture 8 - CF: Molecular Basis
In general what does the mutation...,
Which gene is mutated,
What is the cftr protein
50
cards
Lecture 9 - Clinical Genetics
What is the pattern of inheritanc...,
Which ethnicity is most affected ...,
What is the incidence of cf
40
cards
Lecture 10 - CF: Respiratory System
Describe the anatomy of the respi...,
What is the difference between th...,
What are the phases of lung devel...
65
cards
Lecture 12 - CF - Therapies
List the main therapies of cf,
What are the goals of cf treatment,
Describe the physiotherapy
40
cards
Lecture 13 - HIV - Virology, Epidemiology, Immunology
How many people in the world are ...,
Which parts of the world are most...,
Describe the trend in rate of hiv...
60
cards
Lecture 14 - HIV - Natural History, Treatment, Prevention
What is the clinical hallmark of ...,
When is hiv first seen in plasma,
What is the virus doing during cl...
61
cards
Lecture 15 - HIV - Cures
What are the differences between ...,
What are some unique cases of cur...,
How do latent infected t cells ar...
18
cards
Lecture 16 - Malaria 1
Which infectious diseases are in ...,
What is the phylum and genus of m...,
Why is malaria an ancient problem
51
cards
Lecture 17 - Malaria 2
Describe variability in var genes...,
Describe ectopic recombination,
What are the hundreds of proteins...
39
cards
Lecture 18 - Malaria 3
Compare global burden of p falcip...,
Is malaria ancient or novel,
Which people are at greatest risk...
36
cards
Lecture 19 - Neurodegeneration Introduction
At which point is onset of parkin...,
What is the most important pathol...,
When was the role of dopamine in ...
18
cards
Lecture 20 - Alzheimer's Disease - Molecular Pathogenesis
Describe the discovery of alzheim...,
Is ad a normal part of ageing,
Describe the features of amyloid ...
52
cards
Lecture 21 - Alzheimer's Disease 2
What is most likely the initiatin...,
List the possible neurotoxic mech...,
What is the normal function of nmda
50
cards
Lecture 22 - Motor Neurone Disease
Give a brief description of mnd,
What are the symptoms of mnd,
What are the two forms of motor n...
36
cards
Lecture 23 - Parkinson's Disease
What are the clinical symptoms of...,
What is lost in pd,
At what point does pd present
46
cards
Lecture 24 - Neurodegeneration Therapeutics
What are some possible targets,
Describe how secretases are targe...,
Why did gamma secretase inhibitor...
16
cards
Lecture 25 - Rheumatoid Arthritis - Introduction
How many different types of arthr...,
What is the burden of arthritis,
What is the definition of ra
80
cards
Lecture 26 - Rheumatoid Arthritis - Synovium
What are the layers of healthy sy...,
Describe the intima,
Describe the subintima
64
cards
Lecture 27 - Rheumatoid Arthritis - Bone
Describe the structure of bone,
What is the main protein in bone,
What is the composition of bone
62
cards
Neurodegenerative Disease Comparison
Compare age of onset in ad pd mnd,
Compare protein of interest in ad...,
Compare genes of interest in ad p...
14
cards
Lecture 28 - Rheumatoid Arthritis - Bone in RA
Describe the cells that modulate ...,
What are the key pro inflammatory...,
What are the patterns of bone los...
45
cards
Lecture 29 - Rheumatoid Arthritis - Treatment
What are the phases of clinical t...,
What is spirit 2013,
What are the principles of ra tre...
44
cards
Lecture 30 - Rheumatoid Arthritis - TNF
Which cells synthesise tnf descri...,
When was tnf alpha first discover...,
What are the tnf alpha receptors
48
cards
Lecture 31 - Muscular Dystrophies - Muscle Structure, Function and Neuromuscular Transmission
What are muscle disorders,
Differentiate between myopathies ...,
Outline these features of skeleta...
47
cards
Lecture 32 - Muscular Dystrophies - Molecular Basis
List important proteins in the fo...,
List the features of the dystroph...,
List the features of dmd common c...
34
cards
Lecture 33 - Muscular Dystrophies - Clinical Aspects
List some dystrophinopathies,
Compare the following in dmd and ...,
To where does the dystrophin gene...
43
cards
Lecture 34 - Other Muscular Dystrophies
How are muscular dystophies class...,
Why is it important to make a dia...,
Compare the following in differen...
36
cards
Lecture 35 - Muscular Dystrophies - Clinical Challenges
Describe the make up of the multi...,
Describe genetic counselling and ...,
1 3rd of mutations causing dmd are
42
cards
Lecture 36 - Muscular Dystrophies - Therapies
What are damaged muscle fibres re...,
List the main features of skeleta...,
Compare success with local and sy...
41
cards
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biom30002 - m2m
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