09 - Bordetella Flashcards Preview

004 - Bacteriology > 09 - Bordetella > Flashcards

Flashcards in 09 - Bordetella Deck (25)
Loading flashcards...
1

(Bordetella)

1. gram?

2. shape?

3. oxygen use?

4. motile?

5. hemolytic?

6. Commensals of where?

7. Causes what disease in mammals and birds?

1. negative

2. pleomorphic coccobacilli

3. aerobic - obligate, not able to survive for long periods outside hosts

4. either

5. most are (not avian)

6. upper respiratory tract

7. respriatory disease

2

(Bordetella)

1. eight species

2. all produce what?

3. Have tropism for what?

2. acute or chronic respiratory disease (in various animals, humans, birds)

3. ciliated epithelium

3

4

(Bordetella Toxins)

There are four toxins produced by Bordetella that play a role in important diseases 

1-4. What are they?

1. dermonecrotic toxin

2. tracheal cytotoxin

3. LPS (endotoxin)

4. Adenylate cyclase 

5

(Bordetella Toxins)

(1. Dermonecrotic Toxin)

1. heat labile toxin

2. funcitonally the same as that of P. multocida?

3. smoot muscle of peripheral blood vessels, arterial constriction, ischemia

4. toxin is intracellular, released when?

2. no

4. upon lysis of bacteria

6

(Bordetella toxins)

(2. Tracheal cytotoxin)

1. exhibits trophism for what?

2. causes what?

3. This toxin is released, thus is a what?

1. for ciliated resp epithelium 

2. destruction of ciliated cells

3. cytotoxin

7

(Bordetella Toxins)

(3. Endotoxin)

1. fever, complement activation

(4. Adenylate Cyclase - except B. Avium)

2. inhibits what and what?

3. how does it work?

2. phagocytosis and phagosome-lysosome fusion

3. look at pic

8

(Bordetella Pertusssis)

1. motile?

2. Natural host in what?

1. no

2. humans

9

(Bordetella Pertussis)

 

10

(Bordetella Pertussis)

1. Transmitted by what?

2. What is used as a vaccine?

3. even with vaccines, whooping cough still common in US

4. treatment?

1. aerosol droplets

2. KILLED toxin (protection lasts a few years)

4. erythromicin

11

(Bordetella parapertussis)

1. more or less severe than whopping cough?

2. Recently isolated in what?

1. less

2. sheep (similar to bordetella pertussis)

12

(Bordetella bronchiseptica)

1. aerboic, bipolar

2. motile - peritrichous flagella

3 (pos or neg?) urease, oxidase, catalase?

4. alkalinizes what?

5. What required for primary isolation?

3. pos to all

4. litmus milk

5. blood or serum

13

(Bordetella bronchiseptica)

1. Causes what in swine?

2. In dogs?

3. 

1. atrophic rhinitis (sometimes w. P. multocida)

2. kennel cough (borderlla is most common cause of tracheobronchitis in dogs

14

(What is Kennel Cough?)

 

15

16

PAY ATTENTION TO THIS SLIDE

17

(Bordetella bronchiseptica)

18

19

20

(Bordetella Avium)

1. B. avium resembles B. bronchiseptica in its growth and culutral characteisisc

2. How is it different?

2. doesn't produce urease

21

(Bordetella Avium)

1. highly contagious upper respiratory tract disease of what?

2. morbidity? mortality?

3. causes what?

4. aka?

5. Infection is spread how?

1. poults

2. high, low

3. rhinotrachetis

4. TURKEY CORYZA

5. direct contact, by aerosols and environmental sources

22

(Bordetella Avium)

1. 

23

24

25

(Bordetella)

(susceptible to...)

1. disinfectants

2. broad-spec antibiotics

3. polymixin

4. penicillin

1-3. yes

4. no