1. Intro to Genomics Flashcards Preview

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Flashcards in 1. Intro to Genomics Deck (8):
1

What is genomics?

Study of the entire DNA sequence that contains the complete set of genes for an organism

2

What is Genetics?

Study of how traits are passed down the generations and the role of genes in that process

3

How do you get a protein from DNA?

DNA is transcribed into RNA.
RNA is translated into protein.

4

What is transcriptome and proteome?

- Transcriptome: total RNA content
- Proteome: total protein content produced

5

What is transcriptomics?

Study off all RNA transcripts produced by a cell, tissue, organism

6

What is NGS, SNPs and GWAS?

NGS: next generation sequencing
SNPs: Single nucleotide polymorphisms
GWAS: Genome-wide association study

7

Relationship between microarrays and NGS.

- Microarrays were used before NGS.
- Microarrays are still used sometimes because they're cheaper. (But NGS is becoming cheaper overtime).
- Microarrays are used to carry out GWAS.

8

Other genomes

- Mitochondrial
- Epigenome: changes in marks on DNA and histones.
- Metagenome : genomes of all the organisms from a specific location.