1. Overview (Lecture)

Question 1

It is the study of immunity

The ways in which the immune system can be advantageously manipulated to protect against or treat diseases

More of concept

Answer 1

Immunology

Question 2

The ability of an organisms to resist infections or disease

Answer 2

Immunity

Question 3

The study of the fluid components of the blood especially antibodies

More of application

Answer 3

Serology

Question 4

Most frequently encountered specimen in immunologic testing

Answer 4

Serum

Question 5

NOTE: Serum is used to identify antigen and antibodies

Question 6

Differentiate the recognize self from non-self

Answer 6

Immuno tolerance

Question 7

Natural resistance, recovery and acquired resistance to infectious diseases

Answer 7

Desirable effects of IRs

Question 8

Hypersensitivity, allograft rejection, autoimmune diseases

Answer 8

Undesirable effects of IRs

Question 9

NOTE: Non-Self materials range from infectious microorganisms to life-saving organ transplantation

Question 10

Describes a plague in Athens during the Peloponnesian war

Meaning: Those who recovered from the plague could nurse the sick without being infected

Answer 10

Thucydides (430 BC)

Question 11

What year chinese developed a custom of inhaling crusts from smallpox lesions to prevent the development of smallpox later in life

Answer 11

1500 AD

Question 12

Causative agent of smallpox?

Answer 12

Variola virus

Question 13

Introduced the practice of Variolation to western medicine

Answer 13

Lady Mary Wortley Montagu 1718

Question 14

NOTE: Smallpox Contains Virulent Virus

Question 15

Injecting materials from smallpox blisters; widely practiced in eastern medicine

Answer 15

Variolation

Question 16

Variolation came from Infected person meaning, it contains virulent virus

Question 17

Considered the father of immunology

Who discovered the smallpox vaccine

Answer 17

Edward Jenner 1798

Question 18

NOTE: Edward Jenner He noticed that milkmaids who contracted cowpox were spared from smallpox epidemics

This then inoculated to a boy to inject cowpox blisters which provides immunity to smallpox

Question 19

Vaccination came from the word Vacca meaning?

Answer 19

Cow

Question 20

Immunity developed from one disease will also be effective to another

Ex. Cowpox and smallpox

Answer 20

Cross immunity

Question 21

Father of modern microbiology

Discovered attenuated (Weakened or killed) vaccines

Discovered vaccines against rabies, Anthrax, and chicken cholera

(Can be considered as the father of immunology)

Answer 21

Louis Pasteur

Question 22

Causative agent of chicken pox?

Answer 22

Varicella zoster virus

Question 23

The ability to triggered immune responce

Answer 23

Immunogenicity

Question 24

Cellular theory f immunity through phagocytsis

Experimented on starfish larvae

Answer 24

Elie Metchnikoff (1880-1900)

Question 25

Factors that are dissolved in the blood (Soluble factors)

Answer 25

Humoral factors

Question 26

NOTE: The theory of phagocytosis is not well accepted because of humoral factors not until Opsonins was discovered

Question 27

Antigen-antibody binding is also known as?

Answer 27

Lattice hypothesis

Question 28

glycoproteins produced by the immune system in response to exposure from an immunogenic material Hallmark of immunogenic material

Answer 28

Antibody

Question 29

Antibody is also known as?

Answer 29

Immunoglobulin or gamma globulin

Question 30

Any material that is capable of binding to the product of an immuno response

Answer 30

Antigen

Question 31

Any material that is capable of eliciting an immune response in an immunocompetent host

Answer 31

Immunogen

Question 32

NOTE: ALL immunogens are Antigens

Question 33

NOTE: Not ALL antigens are immunogens

Question 34

The reaction of the immune system to immunogenic stimulation

Answer 34

Immune response

Question 35

A form of immune defense represented by antiodies and other soluble factors in the blood and body fluids

Answer 35

Humoral immunity

Question 36

A form of immune defense represented by immune cells such as lymphocytes, phagocytic cells, antigen-presenting cells and inflammatory cells.

Answer 36

Cell mediated immunity

Question 37

Basis for the vaccination wherein the pathogens became less virulent, can be weaken or be killed

Answer 37

Attenuation

Question 38

Where did Eli Metchnikoff observe phagocytosis?

Answer 38

Starfish Larvae