Microbiology 3s - Infection CPC

Question 1

• PCP typical picture

Answer 1

o “CXR fairly normal, CT ground glass shadowing bilaterally, SOBOE”

Question 2

• Stain used for PCP

Answer 2

o Methenamine Silver stain / Grocott-Gomori

Question 3

• Antibiotic used to treat PCP

Answer 3

Co-trimoxazole

Question 4

• Where does HIV tend to target?

Answer 4

GALT

Question 5

• When cD4+ <100, which infections are you most at risk to?

Answer 5

CMV, MAC, Lymphoma

Question 6

• Which fungal inectino are people who are neutropaenic at risk of?

Answer 6

Aspergillus

Question 7

• Alcoholic immunodeficient patients prone to…

Answer 7

Actinomyces lung abscess (branching gram +Ve rod)

Question 8

• Why might rifampicin be added to flucloxacillin in treatment of osteomyelitis?

Answer 8

o Has good penetration and can disrupt biofilms so particularly useful when metal prosthetics are used

Question 9

• What is the most important part of prosthetic joint infection management?>

Answer 9

o Removal of prosthesis + adequate debridement

Question 10

• Is alcohol gel effective against C.diff?

Answer 10

o No as it forms spores so need to use soap

Question 11

• How long do you treat C.diff for?

Answer 11

o 14 days

Question 12

• How do you treat c.diff + colonic dilatation?

Answer 12

o mETRO + Vanc

Question 13

• Which ribotype of c.diff = superbug?

Answer 13

Ribotype 027

Question 14

• How do PPIs make you more prone to C.diff?

Answer 14

o Raise gastric pH meaning that more c.diff spores can survive

Question 15

• CRP + WCC in C.diff

Answer 15

o High WCC, low CRP